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Tumor dormancy therapy for the human adenoid cystic carcinoma

Research Project

Project/Area Number 21792009
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionEhime University

Principal Investigator

SUMIDA Tomoki  Ehime University, 医学部附属病院, 講師 (50314951)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords腺様嚢胞癌 / ID1 / エストロゲンレセプター / アンドロゲンレセプター
Research Abstract

In this study, we confirmed that hormonal therapy and Id1 targeting therapy could reduce the growth and invasion of adenoid cystic carcinoma cells. These results indicate that this strategy has a potential for the tumor dormancy therapy for the human adenoid cystic carcinoma.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2011 2010 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Silencing Id-1 inhibits lymphangiogenesis through down-regulation of VEGF-C in oral squamous cell carcinoma.2011

    • Author(s)
      Z Dong, F Wei, C Zhou, T sumida, H Hamakawa, Y Hu, S Liu.
    • Journal Title

      Oral Oncol. 47(1)

      Pages: 27-32

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Silencing Id-1 inhibits lymphangiogenesis through down-regulati on of VEGF-C in oral squamous cell carcinoma.2011

    • Author(s)
      Z Dong, F Wei, C Zhou, T sumida, H Hamakawa, Y Hu, S Liu
    • Journal Title

      Oral Oncology

      Volume: 47 Pages: 27-32

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overexpression of Id-1 Is Associated with Tumor Angiogenesis and Poor Clinical Outcome in Oral Squamous Cell Carcinoma.2010

    • Author(s)
      Z Dong, S Liu, C Zhou, T Sumida, H Hamakawa, Z Chena, P Liu, F Wei.
    • Journal Title

      Oral Oncol. 46(3)

      Pages: 154-157

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 悪性唾液腺腫瘍におけるホルモン療法の可能性2010

    • Author(s)
      住田知樹、石川詔子、浜川裕之
    • Journal Title

      日本口腔組織培養学会誌 18(2)

      Pages: 13-18

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Overexpression of Id-1 Is Associated with Tumor Angiogenesis and Poor Clinical Outcome in Oral Squamous Cell Carcinoma.2010

    • Author(s)
      Z Dong, S Liu, C Zhou, T Sumida, H Hamakawa, Z Chena, P Liu, F Wei.
    • Journal Title

      Oral Oncology

      Volume: 46 Pages: 154-157

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 悪性唾液腺腫瘍におけるホルモン療法の可能性2010

    • Author(s)
      住田知樹、石川詔子、浜川裕之
    • Journal Title

      日本口腔組織培養学会誌

      Volume: 18 Pages: 13-18

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 性ステロイドホルモンが腺様嚢胞癌細胞の運動能、接着に及ぼす影響に関する検討2010

    • Author(s)
      住田知樹、石川詔子、浜川知大、藤田陽平、西川由希子、中城公一、浜川裕之
    • Organizer
      日本口腔科学会総会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-06-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 性ステロイドホルモンが腺様嚢胞癌細胞の運動能、接着に及ぼす影響に関する検討2010

    • Author(s)
      住田知樹、石川詔子、浜川知大、藤田陽平、西川由希子、中城公一、浜川裕之
    • Organizer
      日本口腔科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://emedical.s317.xrea.com/contents/?cat=6

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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