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Development of the prevention program adapting 3DS from the systemic bacterial infection for the children under immunity control before Hemopoietic stem cell transplantation

Research Project

Project/Area Number 21792073
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionHiroshima University

Principal Investigator

KADOMOTO Noriko  広島大学, 大学院・医歯薬学総合研究科, 助教 (10508104)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords3DS / 感染予防 / 免疫抑制 / 造血幹細胞移植
Research Abstract

We developed a new oral prevention program adapting 3DS(Dental Drug Delivery System). When we applied the new program for the children under immunity control before Hemopoietic stem cell transplantation, the number of bacteria in the mouth decreased and it maintained the low value for 3 months. And the program made less inflammation of oral mucous membrane than usual. Therefore, the new 3DS prevention program can decrease the risk of the children' s systemic bacterial infection, and it can improve their Quality of Life.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (5 results)

All 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] 横紋筋肉腫治療のために造血幹細胞移植を行った患児の歯科治療と口腔管理2010

    • Author(s)
      坪井文, 海原康孝, 角本法子, 光畑智恵子, 香西克之
    • Journal Title

      日本歯科医療福祉学会雑誌

      Volume: 15 Pages: 18-23

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 横紋筋肉腫のために造血幹細胞移植を行った患児の歯科治療と口腔管理2010

    • Author(s)
      坪井文, 角本法子, ら
    • Journal Title

      日本歯科医療福祉学会雑誌

      Volume: 15巻1号 Pages: 18-23

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 免疫抑制児の口腔環境と歯科的対応2010

    • Author(s)
      坪井文, 鈴木淳司, 吉村剛, 海原康孝, 中岡美由紀, 角本法子, 大谷聡子, 大原紫, 松浦和則, 香西克之
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-05-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 免疫抑制児の口腔環境と歯科的対応2010

    • Author(s)
      角本法子
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 当科における発達障害児への対応(テーブルディスカッション)2009

    • Author(s)
      角本法子
    • Organizer
      第28回日本小児歯科学会中国四国地方会
    • Place of Presentation
      広島市
    • Year and Date
      2009-11-15
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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