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Relationship between leptin and orofacial development in fetus.

Research Project

Project/Area Number 21792082
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionNiigata University (2010)
Kyushu University (2009)

Principal Investigator

NAKAMURA Yuki  Niigata University, 医歯学系, 助教 (70452779)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords発生・分化 / 胎児発育 / レプチン / 細胞・組織
Research Abstract

From previous research results related to this study clarified that leptin also acts on taste organ. We found that taste organ is also the site of action of leptin. The results of this experiment could not confirm the expression of leptin receptor in fetal mouse mandible. If no expression of leptin receptor in the jaw of a fetus, the possibility of direct action of leptin to the jaw development is considered to be low. However, the possibility that leptin is involved in the orofacial development mediated the central system, is a subject of future investigation.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (6 results)

All 2010

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results)

  • [Journal Article] 総説:飽食ホルモン・レプチンによる甘味感受性の抑制と食調節2010

    • Author(s)
      中村由紀
    • Journal Title

      小児歯科学会雑誌 48巻(4)

      Pages: 505-510

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 総説味覚と肥満2010

    • Author(s)
      重村憲徳, 中村由紀, 二ノ宮裕三
    • Journal Title

      日本咀嚼学会誌 20(1)

      Pages: 48-55

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 総説:飽食ホルモン・レプチンによる甘味感受性の抑制と食調節2010

    • Author(s)
      中村由紀
    • Journal Title

      小児歯科学会雑誌

      Volume: 48巻(4) Pages: 505-510

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 総説:味覚と肥満2010

    • Author(s)
      重村憲徳, 他
    • Journal Title

      日本咀嚼学会雑誌

      Volume: 20巻(1) Pages: 48-55

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 奨励賞受賞講演:飽食ホルモン・レプチンによる甘味感受性の抑制と食調節2010

    • Author(s)
      中村由紀
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 飽食ホルモン・レプチンによる甘味感受性の抑制と食調節2010

    • Author(s)
      中村由紀
    • Organizer
      第48回有限責任中間法人日本小児歯科学会大会,奨励賞受賞講演
    • Place of Presentation
      名古屋(名古屋国際会議場)ホームページ等
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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