The function of anti-cardiolipin antibody by periodontal pathogen for pre-term low birth weight
Project/Area Number |
21792111
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Periodontal dentistry
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
KATAGIRI Sayaka Tokyo Medical and Dental University, 歯学部附属病院, 医員 (60510352)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 歯周病 / 妊娠 / 早期低体重児出産 / 自己抗体 / anti-cardiolipin抗体 / 交差反応 / 早期低体重出産 |
Research Abstract |
Beta 2 glycoprotein I is important in the suppression of coagulation which can inhibit Antiphospholipid syndrome (APS). We showed the possibility of cross reaction between the antibodies of leucotoxin C in A. actinomycetencomitans and TLRVYK peptide on beta 2 GPI. We also showed that patients with low birth weight had significant deep periodontal pockets than normal pregnant women. These result suggested that there are some relations between periodontal diseases and low birth weight.
|
Report
(3 results)
Research Products
(37 results)
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[Journal Article] Reduced masticatory function in non-elderly obese Japanese adults.2011
Author(s)
Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Miyazaki S, Miyauchi T, Nakamura N, Oseko F, Kanamura N, Ando Y, Hanada N, Inoue S.
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Journal Title
Obesity Research and Clinical Practice in press
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[Journal Article] Relationship between Periodontitis and Diabetes-Importance of a Clinical Study to Prove the Vicious Cycle.2010
Author(s)
Nagasawa T, Mitsuhiko Noda, Katagiri S, Takaichi M, Takahashi Y, Wara-Aswapati N, Kobayashi H, Ohara S, Kawaguchi Y, Tagami T, Furuichi Y, Izumi Y.
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Journal Title
Internal Medicine 49(10)
Pages: 881-885
NAID
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[Journal Article] High prevalence of periodontitis in non-elderly obese Japanese adults.2010
Author(s)
Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Miyazaki S, Miyauchi T, Nakamura N, Kanamura N, Ando Y, Hanada N, Inoue S.
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Journal Title
Obesity Research and Clinical Practice 4
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[Presentation] 犬の破切歯における回顧的研究 -205症例について-
Author(s)
高橋香, 藤田理恵子, 三浦紫陽子, 戸野倉雅美, 田熊大祐, 馬場亮, 松木薗麻里子, 難波直, 笹原沙衣子, 鴇田真弓, 市橋弘章, 伊藤寛恵, 佐藤雅美, 高畠正義, 文原千尋, 藤野浩子, 小暮啓介, 押田智枝, 片桐さやか, 藤田桂一
Organizer
日本獣医内科学アカデミー/日本獣医臨床病理学会/日本獣医皮膚科学会
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