Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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Research Abstract |
Nicotine induces the expression of CA II, inflammatory cytokines and PGE2 in osteoclast precursors. In the presence of COX-2 inhibitor , nicotine did not induce CA II expression. These results suggest that PGE2 play a role in the induction of CA II expression by autocrine manner.
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