The role of interleukin 35, the novel cytokine, in the human periodontal tissue.
| Project/Area Number |
21792134
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Periodontal dentistry
|
|---|
| Research Institution | Aichi Gakuin University |
|---|
Principal Investigator |
MITANI Akio Aichi Gakuin University, 歯学部, 講師 (50329611)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | IL-35 / 歯周組織 / 制御性T細胞 / 歯学 / 免疫学 |
|---|
| Research Abstract |
The subunits of IL-35 were detected higher in gingival tissue of patients with periodontitis compare with healthy volunteer. IL-35 protein was also higher in GCF of patients with periodontitis compare with healthy volunteer. Moreover, IL-35 may inhibit the osteoclastogenesis. These results suggest that IL-35 could have the protective role in progression of periodontitis.
|
Report
(3 results)
Research Products
(41 results)
