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The evaluation of oxidative DNA damage in children and adolescence with cerebral palsy using 8-hydroxydeoxyguanosine levels

Research Project

Project/Area Number 21800041
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Rehabilitation science/Welfare engineering
Research InstitutionChiba Prefectural University of Health Sciences

Principal Investigator

HORIMOTO Yoshitaka  Chiba Prefectural University of Health Sciences, 助教 (40555546)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,652,000 (Direct Cost: ¥2,040,000、Indirect Cost: ¥612,000)
Fiscal Year 2010: ¥1,261,000 (Direct Cost: ¥970,000、Indirect Cost: ¥291,000)
Fiscal Year 2009: ¥1,391,000 (Direct Cost: ¥1,070,000、Indirect Cost: ¥321,000)
Keywords脳性麻痺 / DNA損傷修復能力 / 運動
Research Abstract

Urinary levels of 8-hydroxydeoxyguanosine (8-OHdG) were examined to estimate the relevance of oxidative stress in children and adolescence with cerebral palsy (CP). Urinary 8-OHdG levels were measured in 12 children and adolescence with CP and these levels were compared with those in 12 healthy children and adolescence (without CP). There was no significant difference of the mean level of urinary 8-OHdG between children and adolescence with and without CP (11.4±2.0 ng/mg CRE and 8.2±0.9 ng/mg CRE, respectively).

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (10 results)

All 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (3 results) Remarks (1 results)

  • [Journal Article] CT画像を用いた胸骨と脊柱のねじれの定量的評価方法(Green village Method)-検者内、検者間の再現性および信頼性の検討2009

    • Author(s)
      堀本佳誉、大須田祐亮、高田千春、前田美穂、小玉武志、高橋奈津美、鈴木敦史、小塚直樹、津川敏
    • Journal Title

      重症心身障害学会誌 34

      Pages: 429-434

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 精神障害のある子どもの運動2009

    • Author(s)
      吉田晋、堀本佳誉、清水栄司
    • Journal Title

      体育の科学 59

      Pages: 825-828

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 評価に基づいた理学療法:小児「脳性麻痺」2009

    • Author(s)
      小塚直樹、西部寿人、樋室伸顕、大須田祐亮、堀本佳誉、横井裕一郎
    • Journal Title

      理学療法学 36

      Pages: 232-235

    • NAID

      110007333892

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 多チャンネル近赤外線分光法を用いた重症心身障害児(者)に対する視覚機能評価の試み2009

    • Author(s)
      中村裕二、仙石泰仁、中島そのみ、堀本佳誉、須鎌康介、津川敏
    • Journal Title

      重症心身障害学会誌 34

      Pages: 421-427

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aprataxin遺伝子変異(689insT)が認められた眼球運動失行を伴う失調症(Ataxia-oculomotor apraxia ; AOA1)患者の臨床症状2009

    • Author(s)
      堀本佳誉、菊池真、大須田祐亮、舘延忠、小塚直樹
    • Journal Title

      理学療法学 36

      Pages: 317-323

    • NAID

      110007467996

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 臥位保持具の使用により呼吸器疾患の発生頻度が減少した一事例2009

    • Author(s)
      堀本佳誉、高田千春、大須田祐亮、須鎌康介、小玉武志、高橋奈津美、佐藤匠、前田美穂、山田貴子
    • Journal Title

      重症心身障害の療育 4

      Pages: 213-215

    • NAID

      40016752819

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] CT画像を用いた胸郭の厚さと幅の計測法-2つの方法の比較-2009

    • Author(s)
      堀本佳誉、高田千春、大須田祐亮、近藤健、鈴木敦史、前田美穂、山田貴子、須鎌康介、小玉武志、高橋奈津美、佐藤匠、津川敏
    • Organizer
      第35回日本重症心身障害学会
    • Place of Presentation
      新潟県長岡市 ニューオータニ長岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] CT画像を用いた胸郭の厚さと幅の計測法-信頼性の検討-2009

    • Author(s)
      堀本佳誉、高田千春、大須田祐亮、近藤健、鈴木敦史、前田美穂、山田貴子、須鎌康介、小玉武志、高橋奈津美、佐藤匠、津川敏
    • Organizer
      第35回日本重症心身障害学会
    • Place of Presentation
      新潟県長岡市 ニューオータニ長岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] CT画像を用いた重症心身障害児・者の変形の定量的測定方法-第五報 胸郭の厚さと幅の計測法-2009

    • Author(s)
      堀本佳誉、高田千春、大須田祐亮、小玉武志、高橋奈津美、山田貴子、佐藤匠、須鎌康介、前田美穂、竹内孝子、津川敏、小塚直樹
    • Organizer
      第44回日本理学療法学術大会
    • Place of Presentation
      東京都 東京国際フォーラム
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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