| Budget Amount *help |
¥2,756,000 (Direct Cost: ¥2,120,000、Indirect Cost: ¥636,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
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| Research Abstract |
REM sleep, a physiologic state responsible for dreaming, is unique to certain vertebrate species and thus might be involved in higher-order brain functions. Yet the roles of REM sleep remain elusive. Here, to overcome the problems of conventional methods to inhibit REM sleep (side-effects such as stress and rebound), I adopted a genetic approach. I established transgenic mice in which a neural-activity inhibiting gene can be induced specifically in the REM sleep center.
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