• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Genetic analyses of the function of REM sleep

Research Project

Project/Area Number 21800090
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

HAYASHI Yu  The Institute of Physical and Chemical Research, 行動遺伝学技術開発チーム, 基礎科学特別研究員 (40525812)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,756,000 (Direct Cost: ¥2,120,000、Indirect Cost: ¥636,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
KeywordsREM睡眠 / マウス / 遺伝学
Research Abstract

REM sleep, a physiologic state responsible for dreaming, is unique to certain vertebrate species and thus might be involved in higher-order brain functions. Yet the roles of REM sleep remain elusive. Here, to overcome the problems of conventional methods to inhibit REM sleep (side-effects such as stress and rebound), I adopted a genetic approach. I established transgenic mice in which a neural-activity inhibiting gene can be induced specifically in the REM sleep center.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (7 results)

All 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] ニューロン同士をつなぐ神経突起の除去か維持かの決定におけるWnt-Ror経路の役割2010

    • Author(s)
      林悠
    • Journal Title

      実験医学 28(1)

      Pages: 78-81

    • Related Report
      2010 Final Research Report
  • [Journal Article] ニューロン同士をつなぐ神経突起の除去か維持かの決定におけるWnt-Ror経路の役割2010

    • Author(s)
      林悠
    • Journal Title

      実験医学 28

      Pages: 78-81

    • Related Report
      2009 Annual Research Report
  • [Journal Article] A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans.2009

    • Author(s)
      Hayashi Yu, Hirotsu Takaaki, Iwata Ryo, Kage-Nakadai Eriko, Kunitomo Hirofumi, Ishihara Takeshi, Iino Yuichi, Kubo Takeo
    • Journal Title

      Nature Neuroscience 12(8)

      Pages: 981-7

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Atrophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans2009

    • Author(s)
      Hayashi Y, Hirotsu T, Iwata R, Kage-Nakadai E, Kunitomo H, Ishihara T, Iino Y, Kubo T
    • Journal Title

      Nature Neuroscience 12

      Pages: 981-987

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] マウス遺伝学的手法によるREM睡眠中枢ニューロンの解析2010

    • Author(s)
      林悠
    • Organizer
      日本睡眠学会第36回定期学術集会・シンポジウム「睡眠・覚醒の神経機構を探る戦略」
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-01
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス遺伝学的手法によるREM睡眠中枢ニューロンの解析2010

    • Author(s)
      林悠
    • Organizer
      日本睡眠学会第36回定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-01
    • Related Report
      2010 Annual Research Report
  • [Remarks] 研究室ホームページ

    • URL

      http://bgshige.brain.riken.jp/indexj.htm

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi