| Project/Area Number |
21810001
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental impact assessment/Environmental policy
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| Research Institution | Hokkaido University |
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Principal Investigator |
IKENAKA Yoshinori Hokkaido University, (連合)大学院・獣医学研究科, 講師 (40543509)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,756,000 (Direct Cost: ¥2,120,000、Indirect Cost: ¥636,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
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| Keywords | 免疫かく乱 / 環境汚染バイオマーカー / 重金属 / アフリカ / 飼育動物 / GIS / 環境化学物質 / 感染症 / 免疫抑制 / サイトカイン / インターロイキン / アフリカ地域 / メタロチオネイン / 野生動物 |
|---|
| Research Abstract |
We investigated about "disease for wildlife caused by environmental chemicals", in particular "immunosuppression" focusing on at the field level. We did our investigation in Republic of Zambia the major industry of the country is mining activity. From our results, we found that due to mining activity, the inflammatory cytokines levels and oxidative stress marker levels in domestic cattle and wild rodents were consider affected by heavy metals exposure. Furthermore, we analyze the correlation between GIS heavy metal concentration data and immune disruption. The results indicated that we couldn't found any correlations among immune disruption, heavy metal concentration in soil, and MT expression levels. Our results suggested that other strong factors such as feeding habitat, infection are affected to the correlation.
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