| Budget Amount *help |
¥2,574,000 (Direct Cost: ¥1,980,000、Indirect Cost: ¥594,000)
Fiscal Year 2010: ¥1,222,000 (Direct Cost: ¥940,000、Indirect Cost: ¥282,000)
Fiscal Year 2009: ¥1,352,000 (Direct Cost: ¥1,040,000、Indirect Cost: ¥312,000)
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| Research Abstract |
The purpose of this research project is to verify that capping can occur in cytoplasm as well as nucleus, and show the significance of cytoplasmic capping in gene expression. I identified many target mRNAs to which cap structures would be added in cytoplasm. Also, deep sequencing analysis suggested that some of these mRNAs might have poly(U) tail at 3' terminus. These modifications on mRNA may play important roles in gene expression. In a different research project, I showed that bacteriophage T4 had an antitoxin against E.coli toxins for its own survival.
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