The analysis of the regulation mechanisms of plant immune receptors
| Project/Area Number |
21870044
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
KADOTA Yasuhiro The Institute of Physical and Chemical Research, 植物免疫研究グループ, 基礎科学特別研究員 (80548975)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,756,000 (Direct Cost: ¥2,120,000、Indirect Cost: ¥636,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
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| Keywords | 植物免疫 / 分子シャペロン / 抵抗性蛋白質 / 蛋白質立体構造解析 / 病害抵抗性 |
|---|
| Research Abstract |
Hsp90-mediated function of nucleotide-binding leucine-rich repeat receptors (NLR protein) in plant and animal innate immunity depends on the cochaperone Sgt1 and, at least in plants, on Rar1. Both RAR1 and SGT1 domains are independently capable of interacting with the molecular chaperone Hsp90 and can coexist in complexes with Hsp90. We have determined the core structure of an Hsp90-SGT1-RAR1 ternary complex. Mutational and biochemical analyses define the architecture of the ternary complex that recruits NLR proteins by manipulating the structural elements to control the ATPase-dependent conformational cycle of the chaperone.
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Report
(3 results)
Research Products
(31 results)
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[Journal Article] Negative feedback regulation of microbe-associated molecular pattern-induced cytosolic Ca^<2+> transients by protein phosphorylation.
Author(s)
Kurusu T, Hamada H, Sugiyama Y, Yagala T, Kadota Y, Furuichi T, Hayashi T, Umemura K, Komatsu S, Miyao A, Hirochika H, Kuchitsu K
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Journal Title
Journal of Plant Research. (in press)
NAID
Related Report
Peer Reviewed
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[Presentation] ジャガイモ疫病菌エフェクターAVR3aの構造機能解析2011
Author(s)
八丈野孝,門田康弘,瀧澤香,李華,大沢登,半田徳子,寺田貴帆,小柴生造,白水美香子,渡部暁,木川隆則,横山茂之,Sophien Kamoun,白須賢
Organizer
日本植物病理学会2010年度大会
Place of Presentation
東京農工大学
Year and Date
2011-03-28
Related Report
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[Presentation] ジャガイモ疫病菌エフェクターAVR3aの立体構造および機能解析」2011
Author(s)
八丈野孝,門田康弘,瀧澤香,李華,大沢登,半田徳子,寺田貴帆,小柴生造,白水美香子,渡部暁,木川隆則,横山茂之,Sophien Kamoun,白須賢
Place of Presentation
東北大学
Year and Date
2011-03-20
Related Report
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