Molecular mechanism of trans-translation
Project/Area Number |
21880009
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Applied biochemistry
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Research Institution | Hirosaki University |
Principal Investigator |
KURITA Daisuke 弘前大学, 農学生命科学部, 助教 (60552651)
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Project Period (FY) |
2009 – 2010
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Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥2,756,000 (Direct Cost: ¥2,120,000、Indirect Cost: ¥636,000)
Fiscal Year 2010: ¥1,313,000 (Direct Cost: ¥1,010,000、Indirect Cost: ¥303,000)
Fiscal Year 2009: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
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Keywords | tmRNA,SmpB,リボソーム / トランス翻訳 / tmRNA / SmpB / トランス・トランスレーション / リボソーム / 分子擬態 / 翻訳 |
Research Abstract |
To reveal the molecular mechanism of trans-translation, we developed in vitro trans-translation system using purified factors. Using this system, we showed that the C-terminal domain of SmpB plays a role in accommodation of tmRNA into the ribosomal A-site.
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Report
(3 results)
Research Products
(37 results)
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[Journal Article]2009
Author(s)
姫野俵太、栗田大輔、武藤〓
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Journal Title
2つのtRNA/mRNAハイブリッド-トランス・トランスレーション-(共立出版)
Pages: 2201-2206
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[Presentation] Structural studies for RsgA/YjeQ, a ribosome maturation factor2010
Author(s)
Takemoto C, Connell SR, Hase Y, Naoe C, Wang H, Kaminishi T, Kikuchi T, Hirata Y, Kurita D, Muto A, Muto Y, Yokoyama S, Himeno H
Organizer
Ribosomes 2010 meeting
Place of Presentation
Orvieto, Italy
Related Report
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[Presentation] Structural studies for RsgA/YjeQ, a ribosome maturation factor2010
Author(s)
Takemoto, C., Connell, S.R., Hase, Y., Naoe, C., Wang, H., Kaminishi, T., Kikuchi, T., Hirata, Y., Kurita, D., Muto, A., Muto, Y., Yokoyama, S., Himeno, H.
Organizer
Ribosomes 2010 Meeting
Place of Presentation
Orvieto, Italy
Related Report
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