The evaluation of salivary MMPs expression in periodontitis patients as a maker of cardiovascular disease

• Project/Area Number: 21890020
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Social dentistry
• Research Institution: Tohoku University
• Principal Investigator: HOSOKAWA Ryoichi Tohoku University, 大学院・歯学研究科, 助教 (40547254)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000); Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
• Keywords: 歯学 / 口腔ケア / 歯周疾患 / 唾液 / メタロプロテアーゼ / 歯周病

Research Abstract

I evaluated salivary MMPs expression in periodontitis patients and cardiovascular disease patients to reveal the correlation between two diseases. MMP-8 expression level in periodontitis patient was higher than that of control. However, there was no significance difference between periodontitis patients and cardiovascular disease patients.

Research Products

• [Remarks] ホームページ等