Metabolic and functional mapping of the spinal cord using 1H-MR spectroscopy

• Project/Area Number: 21890028
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Cerebral neurosurgery
• Research Institution: University of Tsukuba
• Principal Investigator: AKUTSU Hiroyoshi University of Tsukuba, 附属病院, 病院講師 (20547955)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,093,000 (Direct Cost: ¥1,610,000、Indirect Cost: ¥483,000); Fiscal Year 2010: ¥728,000 (Direct Cost: ¥560,000、Indirect Cost: ¥168,000); Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
• Keywords: MRS / 脊髄 / 代謝 / 超高磁場MR装置 / データ取得条件 / 上位頸椎

Research Abstract

Magnetic resonance spectroscopy (MRS) is currently used in the clinical practice for evaluation of metabolites in the human body, especially for differential diagnosis and evaluation of treatment efficacy in intracranial lesions. MRS would be also useful for spinal lesions, but there have been rarely used for spinal lesions, because of artifacts such as pulsation of cerebrospinal fluid or movement of spinal cord itself. In my experiment, MRS proved to be useful in spinal lesions, using ultra high field scanner with high spatial resolution and signal noise ratio.

Research Products

• [Journal Article] ^1H-MRSにおける定量解析が放射線壊死とanaplastic oligodendrogliomaの再発の鑑別に有効だった一例 (2011)
  • Author(s): 磯辺智範、阿久津博義、山本哲哉、椎貝真成、増本智彦、中井啓、高野晋吾、阿武泉、松村明
  • Journal Title: 脳神経外科 vol.39、no.5 Pages: 485-489
  • Peer Reviewed
• [Journal Article] Proton MR spectroscopic finding of hemangioblastoma. A case report. (2010)
  • Author(s): Isobe T, Yamamoto T, Akutsu H, Anno I, Shiigai M, Zaboronok A, Masumoto T, Takano S, Matsumura A
  • Journal Title: Jpn J Radiol vol.28 Pages: 318-321
  • Peer Reviewed
• [Journal Article] Postmortem magnetic resonance imaging dealing with low temperature objects (2010)
  • Author(s): Kobayashi T, Isobe T, Shiotani S, Saito H, Saotome K, Kaga K, Miyamoto K, Kikuchi K, Hayakawa H, Akutsu H, Honma K
  • Journal Title: Magn Reson Med Sci vol.9 Pages: 101-108
  • NAID: 10027851199
  • Peer Reviewed
• [Journal Article] 頭部のMRS:緩和時間の変化と定量化 (2010)
  • Author(s): 磯辺智範、阿久津博義、椎貝真成、増本智彦、只野喜一、平野雄二、佐藤英介、山本哲哉、阿武 泉、松村明
  • Journal Title: 日本磁気共鳴医学会雑誌 vol.30, no.3 Pages: 122-133
  • NAID: 10027851673
  • Peer Reviewed
• [Journal Article] MR技術でわかる脳機能情報 (2010)
  • Author(s): 磯辺智範,佐藤英介,阿久津博義,増本智彦,椎貝真成, 只野喜一,山本哲哉,熊田博明,榮武二,松村明
  • Journal Title: 医学物理 vol.30, Sup.1 Pages: 23-34
• [Journal Article] 頭部のMRS:緩和時間の変化と定量化 (2010)
  • Author(s): 磯辺智範、阿久津博義, 他8名
  • Journal Title: 日本磁気共鳴医学会雑誌 Volume: 30(3) Pages: 122-133
  • NAID: 10027851673
• [Presentation] 解析ソフトの違いによるproton MRSデータへの影響 (2011)
  • Author(s): 磯辺智範、只野喜一、阿久津博義、平野雄二、佐藤英介、山本哲哉、増本智彦
  • Organizer: 日本放射線技術学会
  • Place of Presentation: 横浜
• [Presentation] Evaluation of the metabolism change of the cadaver brain by proton MRS. (2011)
  • Author(s): Isobe T, Akutsu H, Kobayashi T, Tadano K, Hayakawa S, Shiotani S
  • Organizer: European Congress of Radiology 2011
  • Place of Presentation: Vienna, Austria
• [Presentation] Noninvasive Quantification of L-p-boronophenylalanine (BPA) using Proton MR Spectroscopy. (2011)
  • Author(s): Isobe T, Yamamoto Y, Yamamoto T, Kumada H, Akutsu H, Matsumura A, Sakae T
  • Organizer: European Congress of Radiology 2011
  • Place of Presentation: Vienna, Austria
• [Presentation] 1H-MRSにおける脳内代謝物の定量結果は解析ソフトの違いによって影響されるか? (2011)
  • Author(s): 只野喜一、磯辺智範、阿久津博義、山本哲哉、佐藤英介、椎貝真成、平野雄二、増本智彦、松村明
  • Organizer: 第40回日本神経放射線学会
  • Place of Presentation: 品川
• [Presentation] ProtonMRSにおけるsingle voxel法とmulti voxel法の比較 (2011)
  • Author(s): 阿久津博義、磯辺智範、只野喜一、山本哲哉、佐藤英介、椎貝真成、増本智彦、石川栄一、高野晋吾、松村明
  • Organizer: 第40回日本神経放射線学会
  • Place of Presentation: 品川
• [Presentation] ^1H-MR Spectroscopy of the Cervical Spinal Cord at 3Tesla (2010)
  • Author(s): Akutsu H, Isobe T, Yamamoto T, Shiigai M, Masumoto T, Matsumura A
  • Organizer: The 8th Chino-Japanese Friendship Neurosurgery Seminar
  • Place of Presentation: Chengdu, China
  • Year and Date: 2010-06-19
• [Presentation] ^1H-MR Spectroscopy of the Cervical Spinal Cord at 3Tesla (2010)
  • Author(s): Akutsu H, Isobe T, Yamamoto T, Shiigai M, Masumoto T, Matsumura A
  • Organizer: The 8^<th> Chino-Japanese Friendship Neurosurgery Seminar
  • Place of Presentation: 成都、中国(Seito convention center)
  • Year and Date: 2010-06-19
• [Presentation] 3.0T MRIを用いた頸髄1H-MRSの試み (2010)
  • Author(s): 磯辺智範、平野雄二、阿久津博義、只野喜一、山本哲哉、増本智彦、松村明
  • Organizer: 第66回日本放射線技術学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2010-04-11
• [Presentation] 3.OT MRIを用いた頸髄1H-MRSの試み (2010)
  • Author(s): 磯辺智範、阿久津博義, 他5名
  • Organizer: 第66回日本放射線技術学会学術総会
  • Place of Presentation: 横浜(パシフィコ横浜)
  • Year and Date: 2010-04-11
• [Presentation] MR技術でわかる脳機能情報 (2010)
  • Author(s): 磯辺智範、佐藤英介、阿久津博義、増本智彦、椎貝真成、只野喜一、山本哲哉、熊田博明、榮武二、松村明
  • Organizer: 第99回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2010-04-09
• [Presentation] 3 Tesla MR装置を用いた頸髄の1H-MRS (2010)
  • Author(s): 阿久津博義
  • Organizer: 第39回日本神経放射線学会
  • Place of Presentation: 学術総合センター講学堂:東京
  • Year and Date: 2010-02-13
• [Presentation] Multi-voxel proton MRSにおける領域選択の位置ずれに関する基礎的検討 (2010)
  • Author(s): 磯辺智範、阿久津博義、椎貝真成、平野雄二、岡本嘉一、山本哲哉、只野喜一、佐藤英介、阿武泉、鈴木由里子、増本智彦、松村明
  • Organizer: 第38回日本磁気共鳴医学会
  • Place of Presentation: つくば
• [Presentation] First trial for Proton MR Spectroscopy of the Cervical Spinal Cord. (2010)
  • Author(s): Tadano K, Isobe T, Akutsu H, Hirano Y, Shiigai M, Sato E, Nakai K, Yamamoto T, Masumoto T, Matsumura A
  • Organizer: The 15th East Asia Conference of Radiological Technologists
  • Place of Presentation: Tokyo
• [Presentation] Proton MRSによる中枢性神経細胞腫の代謝診断 (2010)
  • Author(s): 相山仁、阿久津博義、磯辺智範、高野晋吾、山本哲哉、鶴淵隆夫、椎貝真成、増本智彦、只野喜一、柴田靖、松村明
  • Organizer: 第39回日本神経放射線学会
  • Place of Presentation: 東京
• [Presentation] 3 Tesla MR装置を用いた頚髄1H-MRS (2010)
  • Author(s): 阿久津博義、磯辺智範、山本哲哉、中井啓、椎貝真成、増本智彦、只野喜一、平野雄二、松村明
  • Organizer: 第39回日本神経放射線学会
  • Place of Presentation: 東京
• [Book] これで安心!診療放射線技師のためのよくわかるオートプシー・イメージング(Ai)検査マニュアル 第1版(阿部一之,樋口清幸,井野賢司編)(第7章各施設での取り組み,MRSを用いたAi撮像) (2010)
  • Author(s): 磯辺智範,阿久津博義,小林智哉,只野喜一,早川秀幸,塩谷清司
  • Total Pages: 127
  • Publisher: ベクトル・コア