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Metabolic and functional mapping of the spinal cord using 1H-MR spectroscopy

Research Project

Project/Area Number 21890028
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionUniversity of Tsukuba

Principal Investigator

AKUTSU Hiroyoshi  University of Tsukuba, 附属病院, 病院講師 (20547955)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,093,000 (Direct Cost: ¥1,610,000、Indirect Cost: ¥483,000)
Fiscal Year 2010: ¥728,000 (Direct Cost: ¥560,000、Indirect Cost: ¥168,000)
Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
KeywordsMRS / 脊髄 / 代謝 / 超高磁場MR装置 / データ取得条件 / 上位頸椎
Research Abstract

Magnetic resonance spectroscopy (MRS) is currently used in the clinical practice for evaluation of metabolites in the human body, especially for differential diagnosis and evaluation of treatment efficacy in intracranial lesions. MRS would be also useful for spinal lesions, but there have been rarely used for spinal lesions, because of artifacts such as pulsation of cerebrospinal fluid or movement of spinal cord itself. In my experiment, MRS proved to be useful in spinal lesions, using ultra high field scanner with high spatial resolution and signal noise ratio.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (22 results)

All 2011 2010

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (15 results) Book (1 results)

  • [Journal Article] ^1H-MRSにおける定量解析が放射線壊死とanaplastic oligodendrogliomaの再発の鑑別に有効だった一例2011

    • Author(s)
      磯辺智範、阿久津博義、山本哲哉、椎貝真成、増本智彦、中井啓、高野晋吾、阿武泉、松村明
    • Journal Title

      脳神経外科 vol.39、no.5

      Pages: 485-489

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proton MR spectroscopic finding of hemangioblastoma. A case report.2010

    • Author(s)
      Isobe T, Yamamoto T, Akutsu H, Anno I, Shiigai M, Zaboronok A, Masumoto T, Takano S, Matsumura A
    • Journal Title

      Jpn J Radiol vol.28

      Pages: 318-321

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Postmortem magnetic resonance imaging dealing with low temperature objects2010

    • Author(s)
      Kobayashi T, Isobe T, Shiotani S, Saito H, Saotome K, Kaga K, Miyamoto K, Kikuchi K, Hayakawa H, Akutsu H, Honma K
    • Journal Title

      Magn Reson Med Sci vol.9

      Pages: 101-108

    • NAID

      10027851199

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 頭部のMRS:緩和時間の変化と定量化2010

    • Author(s)
      磯辺智範、阿久津博義、椎貝真成、増本智彦、只野喜一、平野雄二、佐藤英介、山本哲哉、阿武 泉、松村明
    • Journal Title

      日本磁気共鳴医学会雑誌 vol.30, no.3

      Pages: 122-133

    • NAID

      10027851673

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] MR技術でわかる脳機能情報2010

    • Author(s)
      磯辺智範,佐藤英介,阿久津博義,増本智彦,椎貝真成, 只野喜一,山本哲哉,熊田博明,榮武二,松村明
    • Journal Title

      医学物理 vol.30, Sup.1

      Pages: 23-34

    • Related Report
      2010 Final Research Report
  • [Journal Article] 頭部のMRS:緩和時間の変化と定量化2010

    • Author(s)
      磯辺智範、阿久津博義, 他8名
    • Journal Title

      日本磁気共鳴医学会雑誌

      Volume: 30(3) Pages: 122-133

    • NAID

      10027851673

    • Related Report
      2010 Annual Research Report
  • [Presentation] 解析ソフトの違いによるproton MRSデータへの影響2011

    • Author(s)
      磯辺智範、只野喜一、阿久津博義、平野雄二、佐藤英介、山本哲哉、増本智彦
    • Organizer
      日本放射線技術学会
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] Evaluation of the metabolism change of the cadaver brain by proton MRS.2011

    • Author(s)
      Isobe T, Akutsu H, Kobayashi T, Tadano K, Hayakawa S, Shiotani S
    • Organizer
      European Congress of Radiology 2011
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2010 Final Research Report
  • [Presentation] Noninvasive Quantification of L-p-boronophenylalanine (BPA) using Proton MR Spectroscopy.2011

    • Author(s)
      Isobe T, Yamamoto Y, Yamamoto T, Kumada H, Akutsu H, Matsumura A, Sakae T
    • Organizer
      European Congress of Radiology 2011
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2010 Final Research Report
  • [Presentation] 1H-MRSにおける脳内代謝物の定量結果は解析ソフトの違いによって影響されるか?2011

    • Author(s)
      只野喜一、磯辺智範、阿久津博義、山本哲哉、佐藤英介、椎貝真成、平野雄二、増本智彦、松村明
    • Organizer
      第40回日本神経放射線学会
    • Place of Presentation
      品川
    • Related Report
      2010 Final Research Report
  • [Presentation] ProtonMRSにおけるsingle voxel法とmulti voxel法の比較2011

    • Author(s)
      阿久津博義、磯辺智範、只野喜一、山本哲哉、佐藤英介、椎貝真成、増本智彦、石川栄一、高野晋吾、松村明
    • Organizer
      第40回日本神経放射線学会
    • Place of Presentation
      品川
    • Related Report
      2010 Final Research Report
  • [Presentation] ^1H-MR Spectroscopy of the Cervical Spinal Cord at 3Tesla2010

    • Author(s)
      Akutsu H, Isobe T, Yamamoto T, Shiigai M, Masumoto T, Matsumura A
    • Organizer
      The 8th Chino-Japanese Friendship Neurosurgery Seminar
    • Place of Presentation
      Chengdu, China
    • Year and Date
      2010-06-19
    • Related Report
      2010 Final Research Report
  • [Presentation] ^1H-MR Spectroscopy of the Cervical Spinal Cord at 3Tesla2010

    • Author(s)
      Akutsu H, Isobe T, Yamamoto T, Shiigai M, Masumoto T, Matsumura A
    • Organizer
      The 8^<th> Chino-Japanese Friendship Neurosurgery Seminar
    • Place of Presentation
      成都、中国(Seito convention center)
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 3.0T MRIを用いた頸髄1H-MRSの試み2010

    • Author(s)
      磯辺智範、平野雄二、阿久津博義、只野喜一、山本哲哉、増本智彦、松村明
    • Organizer
      第66回日本放射線技術学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 3.OT MRIを用いた頸髄1H-MRSの試み2010

    • Author(s)
      磯辺智範、阿久津博義, 他5名
    • Organizer
      第66回日本放射線技術学会学術総会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2010-04-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] MR技術でわかる脳機能情報2010

    • Author(s)
      磯辺智範、佐藤英介、阿久津博義、増本智彦、椎貝真成、只野喜一、山本哲哉、熊田博明、榮武二、松村明
    • Organizer
      第99回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 3 Tesla MR装置を用いた頸髄の1H-MRS2010

    • Author(s)
      阿久津博義
    • Organizer
      第39回日本神経放射線学会
    • Place of Presentation
      学術総合センター講学堂:東京
    • Year and Date
      2010-02-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] Multi-voxel proton MRSにおける領域選択の位置ずれに関する基礎的検討2010

    • Author(s)
      磯辺智範、阿久津博義、椎貝真成、平野雄二、岡本嘉一、山本哲哉、只野喜一、佐藤英介、阿武泉、鈴木由里子、増本智彦、松村明
    • Organizer
      第38回日本磁気共鳴医学会
    • Place of Presentation
      つくば
    • Related Report
      2010 Final Research Report
  • [Presentation] First trial for Proton MR Spectroscopy of the Cervical Spinal Cord.2010

    • Author(s)
      Tadano K, Isobe T, Akutsu H, Hirano Y, Shiigai M, Sato E, Nakai K, Yamamoto T, Masumoto T, Matsumura A
    • Organizer
      The 15th East Asia Conference of Radiological Technologists
    • Place of Presentation
      Tokyo
    • Related Report
      2010 Final Research Report
  • [Presentation] Proton MRSによる中枢性神経細胞腫の代謝診断2010

    • Author(s)
      相山仁、阿久津博義、磯辺智範、高野晋吾、山本哲哉、鶴淵隆夫、椎貝真成、増本智彦、只野喜一、柴田靖、松村明
    • Organizer
      第39回日本神経放射線学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 3 Tesla MR装置を用いた頚髄1H-MRS2010

    • Author(s)
      阿久津博義、磯辺智範、山本哲哉、中井啓、椎貝真成、増本智彦、只野喜一、平野雄二、松村明
    • Organizer
      第39回日本神経放射線学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Book] これで安心!診療放射線技師のためのよくわかるオートプシー・イメージング(Ai)検査マニュアル 第1版(阿部一之,樋口清幸,井野賢司編)(第7章各施設での取り組み,MRSを用いたAi撮像)2010

    • Author(s)
      磯辺智範,阿久津博義,小林智哉,只野喜一,早川秀幸,塩谷清司
    • Total Pages
      127
    • Publisher
      ベクトル・コア
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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