Research of central auditory system

• Project/Area Number: 21890088
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Otorhinolaryngology
• Research Institution: Kanazawa University
• Principal Investigator: SUGIMOTO Hisashi Kanazawa University, 医学系, 助教 (20547179)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000); Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
• Keywords: 聴覚中枢 / 先天難聴動物モデル / 先天聾動物モデル

Research Abstract

Hearing loss produced by cochlear damage during early development can result in persistent changes in organization of the central auditory system in adults.
In this research, we successfully made rats model with unilateral cochlear ablation conducted prior to the onset of hearig. Our next research is to investigate the neurochemical and neuroanatomical changes produced in auditory brainstem of these rats.

Research Products

• [Journal Article] A case of chronic otitis media caused by Mycobacterium abscessus (2010)
  • Author(s): Hisashi Sugimoto, Makoto Ito, 他3名
  • Journal Title: Auris Nasus Larynx 37 Pages: 636-639
  • NAID: 120002029020
  • Peer Reviewed
• [Journal Article] Roles of Epithelial-Mesenchymal Transition in squamous cell carcinoma of the temporal bone
  • Author(s): Hisashi Sugimoto, Makoto Ito, 他4名
  • Journal Title: Otology&Neurotology in press
  • NAID: 120002986040
  • Peer Reviewed
• [Journal Article] Concurrent superselective intra-arterial chemotherapy and radiotherapy for late-stage squamous cell carcinoma of the temporal bone
  • Author(s): Hisashi Sugimoto, Makoto Ito, 他4名
  • Journal Title: ANNALS of Otology, Rhinology&Laryngology in press
  • Peer Reviewed
• [Journal Article] Clonal spread of β-lactamase-producing amoxillin-clavulanate-resistant (BLPACR) strains of non-typeable haemophilus influenza among toung children attending a day care in Japan
  • Author(s): Makoto Ito, Hisashi Sugimoto, 他5名
  • Journal Title: International Journal of Pediatric Otorhinolaryngology in press
  • Peer Reviewed
• [Presentation] 聴器扁平上皮癌に対し放射線併用超選択的動注化学療法を行った6症例の検討 (2010)
  • Author(s): 杉本寿史、伊藤真人
  • Organizer: 第20回日本耳科学会
  • Place of Presentation: 愛媛
  • Year and Date: 2010-10-08
• [Presentation] 聴器扁平上皮癌に対し放射線併用超選択的動注化学療法を行った6症例の検討 (2010)
  • Author(s): 杉本寿史
  • Organizer: 第20回日本耳科学会
  • Place of Presentation: ひめぎんホール(愛媛)
  • Year and Date: 2010-10-08
• [Presentation] 側頭骨内髄膜脳瘤に合併した中耳真珠腫の1例 (2010)
  • Author(s): 杉本寿史、伊藤真人
  • Organizer: 第72回耳鼻咽喉科臨床学会
  • Place of Presentation: 岡山
  • Year and Date: 2010-07-02
• [Presentation] 側頭骨内髄膜脳瘤に合併した中耳真珠腫の1例 (2010)
  • Author(s): 杉本寿史
  • Organizer: 第72回耳鼻咽喉科臨床学会
  • Place of Presentation: 倉敷市文芸館(岡山)
  • Year and Date: 2010-07-02
• [Presentation] 側頭骨原発扁平上皮癌の予後因子の解析 (2010)
  • Author(s): 杉本寿史、伊藤真人
  • Organizer: 第111回日本耳鼻咽喉科学会総会
  • Place of Presentation: 宮城
  • Year and Date: 2010-05-21
• [Presentation] 側頭骨原発扁平上皮癌の予後因子の解析 (2010)
  • Author(s): 杉本寿史
  • Organizer: 第111回日本耳鼻咽喉科学会総会
  • Place of Presentation: 仙台国際センター(宮城)
  • Year and Date: 2010-05-21
• [Presentation] Analysis of mechanism of malignancy Enhanced by Epithelial-mesenchimal Transition in Squamous Cell Carcinoma of the temporal bone (2010)
  • Author(s): 杉本寿史、伊藤真人
  • Organizer: 33rd ARO midwinter meeting
  • Place of Presentation: Anaheim, California, USA
• [Presentation] Analysis of mechanism of malignancy Enhanced by Epithelial-mesenchimal Transition in Squamous Cell Carcinoma of the temporal bone (2010)
  • Author(s): 杉本寿史
  • Organizer: 33rd ARO midwinter meeting
  • Place of Presentation: カリフォルニア ディズニーランドホテル (米国)
• [Presentation] 当科における小児人工内耳・再手術症例の検討 (2009)
  • Author(s): 杉本寿史、伊藤真人
  • Organizer: 第19回日本耳科学会
  • Place of Presentation: 東京
• [Presentation] 当科における小児人工内耳・再手術症例の検討 (2009)
  • Author(s): 杉本寿史
  • Organizer: 第19回日本耳科学会
  • Place of Presentation: 京王プラザホテル (東京)