Development of a novel electrode for the nervous system

Research Project

Project/Area Number	21890101
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Orthopaedic surgery
Research Institution	Nagoya University
Principal Investigator	OKUI Nobuyuki Nagoya University, 医学部附属病院, 病院助教 (70547554)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000) Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
Keywords	脱神経筋 / 神経細胞 / basic fibroblast growth factor(FGF) / 電動義手 / FGF / Cybernetics / 後根神経節細胞
Research Abstract	The goal of this experiment is to evaluate transplantation of rat embryonic neurons into adult rat peripheral nerve and the effect of intramuscular administration of FGF-2 with neuron transplantation. We found that neuron transplantation into peripheral nerve formed functional motor units and injection of FGF-2 with neuron transplantation didn't prevent muscle atrophy.