Study on defense mechanisms of bacteria and host cells in infection.
| Project/Area Number |
21890122
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Biological pharmacy
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| Research Institution | Osaka University |
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Principal Investigator |
NISHINO Mitsuko Osaka University, 産業科学研究所, 特任助教(常勤) (30510440)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,652,000 (Direct Cost: ¥2,040,000、Indirect Cost: ¥612,000)
Fiscal Year 2010: ¥1,261,000 (Direct Cost: ¥970,000、Indirect Cost: ¥291,000)
Fiscal Year 2009: ¥1,391,000 (Direct Cost: ¥1,070,000、Indirect Cost: ¥321,000)
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| Keywords | 感染症 / 細菌 / オートファジー / 輸送体 / 多剤耐性菌 / 排出蛋白質 |
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| Research Abstract |
Autophagy is a bulk degradation process in eukaryotic cells and functions as one of defense mechanisms upon bacterial infection. The origin and source of autophagosomal membranes are long-standing questions. We revealed by using both molecular biological tools and electron tomography that the endoplasmic reticulum is a source for autophagosomal membranes.
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Report
(3 results)
Research Products
(48 results)
