| Project/Area Number |
21890128
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka University |
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Principal Investigator |
BABA Sachiko Osaka University, 大学院・医学系研究科, 特任助教(常勤) (90532987)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,366,000 (Direct Cost: ¥1,820,000、Indirect Cost: ¥546,000)
Fiscal Year 2010: ¥1,248,000 (Direct Cost: ¥960,000、Indirect Cost: ¥288,000)
Fiscal Year 2009: ¥1,118,000 (Direct Cost: ¥860,000、Indirect Cost: ¥258,000)
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| Keywords | 初期流産 / 早期流産 / 生活習慣 / 喫煙 / 就労 / 日本 / 流産 / 日本人 / 症例対照研究 |
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| Research Abstract |
In this matched case-control study, we investigated the associations of reproductive and lifestyle characteristics of women with early spontaneous abortion <12 weeks of gestation.
Information was collected through medical records for 430 cases of early spontaneous abortion and 860 controls of term delivery. Two controls were individual-matched to one case according to maternal age (+/-3 years) and calendar year of events (either early spontaneous abortion or delivery). Multivariable conditional odds ratios (ORs) and 95% confidence interval (CI) were calculated with conditional logistic-regression.
The risk of early spontaneous abortions was higher for women with a past history of early spontaneous abortions. Maternal smoking and employment also influence risk. Our finding suggests that for Japanese women, smoking and working may be important public health issue targets for the prevention of early spontaneous abortions.
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