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Brain imaging studies on cognitive distortions and cognitive behavioral therapy in patients with eating disorders

Research Project

Project/Area Number 21890153
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionHiroshima University

Principal Investigator

MIYAKE Yoshie  Hiroshima University, 保健管理センター, 講師 (70548990)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000)
Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
Keywords摂食障害 / 脳機能画像研究 / fMRI / 身体イメージ
Research Abstract

We investigated the functional abnormalities in brain systems during processing of negative stimuli concerning body images in patients with eating disorders. Brain responses were measured using functional magnetic resonance imaging in female patients with eating disorders and healthy young women. Our study showed that distorted cognition of negative stimuli concerning body image in patients with eating disorders were related to enhanced activation in the amygdala and the prefrontal cortex. These abnormal brain functions may help provide better accounts of the psychopathological mechanisms underlying eating disorders.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2011 2010 2009 Other

All Journal Article (11 results) (of which Peer Reviewed: 6 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] 大学メンタルヘルスにおける発達障害について(1)-来所動機や二次的障害などの背景について-2011

    • Author(s)
      三宅典恵
    • Journal Title

      総合保健科学

      Volume: 27 Pages: 9-14

    • NAID

      40019234427

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural processing of negative word stimuli concerning body image in patients with eating disorders : An fMRI study.2010

    • Author(s)
      Y.Miyake, Y.Okamoto, K.Onoda, N.Shirao,, Y.Okamoto,, Y.Otagaki, S.Yamawaki
    • Journal Title

      Neuroimage 50

      Pages: 1333-1339

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain activation during the perception of distorted body images in eating disorders. Psychiatry Research2010

    • Author(s)
      Y.Miyake, Y.Okamoto, K.Onoda, M Kurosaki, N.Shirao, Y.Okamoto, S.Yamawaki
    • Journal Title

      Neuroimaging 181

      Pages: 183-192

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 摂食障害における認知面の理解とアプローチ2010

    • Author(s)
      岡本百合, 三宅典恵, 白尾直子, 岡本泰昌, 山脇成人
    • Journal Title

      精神神経学雑誌 112

      Pages: 741-749

    • NAID

      10028059251

    • Related Report
      2010 Final Research Report
  • [Journal Article] Neural processing of negative word stimuli concerning body image in patients with eating disorders : An fMRI study.2010

    • Author(s)
      YOSHIE MIYAKE
    • Journal Title

      Neuroimage

      Volume: 50 Pages: 1333-1339

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 摂食障害における認知面の理解とアプローチ2010

    • Author(s)
      岡本百合, 三宅典恵
    • Journal Title

      精神神経学雑誌

      Volume: 112 Pages: 741-749

    • NAID

      10028059251

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Brain activation during the perception of distorted body images in eating disorders2010

    • Author(s)
      三宅典恵
    • Journal Title

      Psychiatry Research : Neuroimaging 181

      Pages: 183-192

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 労働者のうつ状態に関する質問紙調査の結果と評価2010

    • Author(s)
      三宅典恵
    • Journal Title

      総合保健科学 26

      Pages: 29-33

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 摂食障害の高次脳機能;身体イメージの認知基盤2009

    • Author(s)
      三宅典恵, 岡本泰昌, 山脇成人
    • Journal Title

      Pharma Medica 27

      Pages: 25-28

    • Related Report
      2010 Final Research Report
  • [Journal Article] 摂食障害治療の最前線摂食障害における脳機能画像研究2009

    • Author(s)
      岡本百合, 岡本泰昌, 三宅典恵, 白尾直子, 黒崎充勇, 山脇成人
    • Journal Title

      心身医学 49

      Pages: 39-45

    • Related Report
      2010 Final Research Report
  • [Journal Article] 摂食障害の高次脳機能;身体イメージの認知基盤2009

    • Author(s)
      三宅典恵
    • Journal Title

      Pharma Medica 27

      Pages: 25-28

    • Related Report
      2009 Annual Research Report
  • [Presentation] 摂食障害の外来診療のためのテキスト作成2011

    • Author(s)
      三宅典恵, 黒崎充勇, 岡本百合
    • Organizer
      第34回日本心身医学会中国・四国地方会
    • Place of Presentation
      松山市
    • Year and Date
      2011-11-06
    • Related Report
      2010 Final Research Report
  • [Presentation] 摂食障害の外来診療のためのテキスト作成2010

    • Author(s)
      三宅典恵
    • Organizer
      第34回日本心身医学会 中国・四国地方会
    • Place of Presentation
      愛媛県松山市
    • Year and Date
      2010-11-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] fMRIを用いた情動刺激に対する神経性無食欲症の反応性とアレキシサイミアの神経相関2010

    • Author(s)
      三宅典恵, 岡本泰昌, 岡本百合, 白尾直子, 黒崎充勇, 大田垣洋子, 山脇成人
    • Organizer
      第14回日本摂食障害学会学術集会
    • Place of Presentation
      東京都
    • Year and Date
      2010-10-03
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 情動刺激に対する神経性無食欲症の反応性とアレキシサイミアの神経相関:fMRI研究2010

    • Author(s)
      三宅典恵, 岡本泰昌, 岡本百合, 萬谷智之, 白尾直子, 黒崎充勇, 大田垣洋子, 高畑紳一, 山脇成人
    • Organizer
      第51回日本心身医学会総会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-06-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 情動刺激に対する神経性無食欲症の反応性とアレキシサイミアの神経相関:fMRI研究2010

    • Author(s)
      三宅典恵
    • Organizer
      第51回日本心身医学会総会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2010-06-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 摂食障害の身体画像刺激に対する脳の反応性の検討;fMRI研究2009

    • Author(s)
      三宅典恵, 岡本泰昌, 岡本百合, 黒崎充勇, 白尾直子, 大田垣洋子, 山脇成人
    • Organizer
      第13回日本摂食障害学会学術集会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-09-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 摂食障害の身体画像刺激に対する脳の反応性の検討:fMRI研究2009

    • Author(s)
      三宅典恵
    • Organizer
      第13回日本摂食障害学会学術集会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] fMRIを用いた身体画像刺激に対する摂食障害の反応性の検討2009

    • Author(s)
      三宅典恵, 岡本泰昌, 白尾直子, 岡本百合, 黒崎充勇, 大田垣洋子, 高畑紳一, 山脇成人
    • Organizer
      第105回日本精神神経学会学術総会
    • Place of Presentation
      神戸市
    • Year and Date
      2009-08-21
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 身体画像刺激に対する摂食障害の反応性:fMRI研究2009

    • Author(s)
      三宅典恵, 岡本泰昌, 白尾直子, 岡本百合, 黒崎充勇, 大田垣洋子, 高畑紳一, 山脇成人
    • Organizer
      第1回日本心身医学5学会合同集会
    • Place of Presentation
      東京都
    • Year and Date
      2009-06-06
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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