Development of the multi-mechanics simulation techniques for the endovascular treatment of cerebral aneurysms with stent grafts

• Project/Area Number: 21890228
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Cerebral neurosurgery
• Research Institution: University of Hyogo
• Principal Investigator: SHIMOGONYA Yuji University of Hyogo, 大学院・工学研究科, 助教 (30552575)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000); Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
• Keywords: 脳動脈瘤 / 血管内治療 / ステントグラフト / 術前評価 / 血流 / 血行力学 / 計算流体力学 / ステント / シミュレーション / モデリング / 数値流体力学

Research Abstract

The influences of the number of strata and the rotation angle in the endovascular treatment with stents on inflow into cerebral aneurysms were examined using computational fluid dynamics approach. Inflow rate into the aneurysm decreased monotonically as the number of strata of the stent increased, while maximum inflow velocity into the aneurysm was fluctuated depending on the strata number. The results also showed that the rotation angle of stent placement in the artery could cause non-negligible effects on the inflow into the aneurysm.

Research Products

• [Journal Article] A realistic simulaton of cerebral aneurysm formation : focusing on a novel hemodynamic index, the gradient oscillatory number (2009)
  • Author(s): Y. Shimogonya, T. Ishikawa, Y. Imai, N. Matsuki, T. Yamaguchi
  • Journal Title: International Journal of Computational Fluid Dynamics 23 Pages: 583-593
  • Peer Reviewed
• [Journal Article] A realistic simulation of saccular cerebral aneurysm formation : focussing on a novel haemodynamic index, the gradient oscillatory number (2009)
  • Author(s): Y.Shimogonya, et al.
  • Journal Title: International Journal of Computational Fluid Dynamics Vol.23 Pages: 583-593
  • Peer Reviewed
• [Presentation] Computational simulation of blood flow dynamics using an anatomically realistic artery model constructed from medical images (2010)
  • Author(s): 下權谷祐児, 伊藤和宏, 熊丸博滋
  • Organizer: World Automation Congress 2010-7th International Forum on Multimedia and Image Processing
  • Place of Presentation: Kobe International Conference Center (Hyogo, Japan)
  • Year and Date: 2010-09-21
• [Presentation] Computational simulation of blood flow dynamics using an anatomically realistic artery model constructed from medical images (2010)
  • Author(s): Y.Shimogonya, et al.
  • Organizer: 7th International Forum on Multimedia and Image Processing
  • Place of Presentation: Kobe International Conference Center(Hyogo, Japan)
  • Year and Date: 2010-09-21
• [Presentation] Hemodynamics in pre-aneurismal artery using virtual removal technique of cerebral aneurysms : the relationship between oscillatory shear stress gradient and aneurysm initiation (2010)
  • Author(s): 下權谷祐児, 伊藤和宏, 熊丸博滋
  • Organizer: LINC Houston 2010 in conjunction with the 7th Intracranial Stent Meeting 2010
  • Place of Presentation: Houston (USA)
  • Year and Date: 2010-09-16
• [Presentation] Hemodynamics in pre-aneurysmal artery using virtual removal technique of cerebral aneurysms : the relationship between oscillatory shear stress gradient and aneurysm initiation (2010)
  • Author(s): Y.Shimogonya, et al.
  • Organizer: Live Interventional Neuroradiology Conference in conjunction with the 7th Intracranial Stent Meeting
  • Place of Presentation: Houston(USA)
  • Year and Date: 2010-09-16
• [Presentation] Pre-aneurysm hemodynamics in a human cerebral artery : the relationship between oscillatory shear stress gradient and aneurysm initiation (2010)
  • Author(s): 下權谷祐児, 伊藤和宏, 熊丸博滋
  • Organizer: 6th World Congress of Biomechanics
  • Place of Presentation: Singapore (Singapore)
  • Year and Date: 2010-08-05
• [Presentation] Pre-aneurysm hemodynamics in a human cerebral artery : the relationship between oscillatory shear stress gradient and aneurysm initiation (2010)
  • Author(s): Y.Shimogonya, et al.
  • Organizer: 6th World Congress of Biomechanics
  • Place of Presentation: Singapore(Singapore)
  • Year and Date: 2010-08-05
• [Presentation] 脳動脈瘤形成部位における瘤形成前の血行力学解析:瘤仮想除去手法の実症例への適用 (2010)
  • Author(s): 下權谷祐児, 熊丸博滋, 伊藤和宏
  • Organizer: 日本機会学会第22回バイオエンジニアリング講演会
  • Place of Presentation: 岡山理科大学(岡山県)
  • Year and Date: 2010-01-10
• [Presentation] 脳動脈瘤形成部位における瘤形成前の血行力学解析:瘤仮想除去法の実症例への適用 (2010)
  • Author(s): 下權谷祐児, 他
  • Organizer: 日本機械学会第22回バイオエンジニアリング講演会
  • Place of Presentation: 岡山理科大学(岡山県)
  • Year and Date: 2010-01-10
• [Presentation] On the sensitivity of a hemodynamic index for cerebral aneurysm initiation (2009)
  • Author(s): Y.Shimogonya, T. Ishikawa, Y. Imai, N. Matsuki, T. Yamaguchi
  • Organizer: the GON, to flow input waveform Bioengineering 2009
  • Place of Presentation: Oxford (UK)
  • Year and Date: 2009-09-24
• [Presentation] On the sensitivity of a hemodynamic index for cerebral aneurysm initiation, the GON, to flow input waveform (2009)
  • Author(s): 下権谷祐児, et al.
  • Organizer: Bioengineering 09
  • Place of Presentation: University of Oxford(UK)
  • Year and Date: 2009-09-24
• [Presentation] Computational techniques for virtual removal of cerebral aneurysms in patient-specific artery models to predict the hemodynamics before aneurysm formation (2009)
  • Author(s): Y.Shimogonya, T. Ishikawa, Y. Imai, N. Matsuki, T. Yamaguchi
  • Organizer: 6th International Intracranial Stent Meeting
  • Place of Presentation: 戦災復興記念館(Miyagi, Japan)
  • Year and Date: 2009-08-06
• [Presentation] Computational techniques for virtual removal of cerebral aneurysms in patient-specific artery models to predict the hemodynamics before aneurysm initiation (2009)
  • Author(s): 下権谷祐児, et al.
  • Organizer: 6th International Intracranial Stent Meeting
  • Place of Presentation: 戦災復興記念館(宮城県)
  • Year and Date: 2009-08-06
• [Remarks] 兵庫県立大学 研究者データベース
  • URL: http://kyoin.u-hyogo.ac.jp/staff/eng/shimogonya/
• [Remarks]
  • URL: http://kyoin.u-hyogo.ac.jp/staff/eng/shimogonya/
• [Remarks]
  • URL: http://kyoin.u-hyogo.ac.jp/staff/eng/shimogonya/