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Subclassification of trigeminal ganglion neurons using electrophysiological properties and effects of inflammation and cancer

Research Project

Project/Area Number 21890234
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionKyushu Dental College

Principal Investigator

XU Shenghong  Kyushu Dental College, 歯学部, 研究員 (50554771)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000)
Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
Keywordsパッチクランプ / 三叉神経節 / 細胞分類 / 炎症 / 癌
Research Abstract

Trigeminal ganglion (TRG) neurons play important roles for transductions of a various sensory inputs (touch, itch, pain and so on) at the orofacial region into the brain. It has been reported that dorsal root ganglion (DRG) neurons can be subclassified into over 9 cell types by using electrophysiological properties. The present study demonstrated that TRG neurons can be also subclassified into 8 cell types by using modified criteria, and the subclassified cell types showed similar characteristics to the matched DRG cell types. Interestingly, there were some chemical differences in a few cell types between the TRG and DRG.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (5 results)

All 2010

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Isolectin B4 binding in populations of rat trigeminal ganglion cells.2010

    • Author(s)
      Ono K, Xu S, Inenaga K.
    • Journal Title

      Neurosci Lett 486(3)

      Pages: 127-131

    • Related Report
      2010 Final Research Report
  • [Journal Article] Electrophysiological and chemical properties in subclassified acutely dissociated cells of rat trigeminal ganglion by current signatures.2010

    • Author(s)
      Xu S, Ono K, Inenaga K.
    • Journal Title

      J Neurophysiol 104(6)

      Pages: 3451-3461

    • Related Report
      2010 Final Research Report
  • [Journal Article] Isolectin B_4 binding in populations of rat trigeminal ganglion cells.2010

    • Author(s)
      Ono K, Xu S, Inenaga K.
    • Journal Title

      Neurosci Lett.

      Volume: 486 Pages: 127-131

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electrophysiological and chemical properties in subclassified acutely dissociated cells of rat trigeminal ganglion by current signatures.2010

    • Author(s)
      Xu-S, Ono K, Inenaga K.
    • Journal Title

      J Neurophysiol.

      Volume: 104 Pages: 3451-3461

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Cell classification for rat trigeminal ganglion neurons by current signatures.2010

    • Author(s)
      Ono K, Xu S, Inenaga K.
    • Organizer
      Annual Meeting Society for Neuroscience
    • Place of Presentation
      San Diego, USA.
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report 2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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