Involvement of the astroglia in pain abnormalities during regeneration of the inferior alveolar nerve in rats

• Project/Area Number: 21890264
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Functional basic dentistry
• Research Institution: Nihon University
• Principal Investigator: HITOMI Suzuro Nihon University, 歯学部, ポスト・ドクトラル・フェロー (70548924)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,509,000 (Direct Cost: ¥1,930,000、Indirect Cost: ¥579,000); Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000); Fiscal Year 2009: ¥1,274,000 (Direct Cost: ¥980,000、Indirect Cost: ¥294,000)
• Keywords: グリア / 神経再生 / 疼痛異常 / 三叉神経 / 延髄 / ニューロン

Research Abstract

Activation of the astroglia in trigeminal spinal subnucleus caudalis and upper cervical spinal cord 1/2 nociceptive neurons and increment in transient receptor potential vanilloid 1-positive neurons in trigeminal ganglion may be involved in the pain abnormalities in the whisker pad during the inferior alveolar nerve regeneration.

Research Products

• [Presentation] Phosphorylation of extracellular signal-regulated kinase in trigeminal spinal subnucleus caudalis neurons during regeneration of the trigeminal nerve in rats. (2010)
  • Author(s): Suzuro Hitomi, Ikuko Suzuki, Koichi Iwata
  • Organizer: 第3回Neuropathic Pain
  • Place of Presentation: Athens, Greece
  • Year and Date: 2010-05-28
• [Presentation] Phosphorylation of extracellular signal-regulated kinase in trigeminal spinal subnucleus caudalis neurons during regeneration of the trigeminal nerve in rats. (2010)
  • Author(s): 人見涼露
  • Organizer: 第3回 Neuropathic Pain
  • Place of Presentation: アテネ(ギリシャ)
  • Year and Date: 2010-05-28
• [Presentation] 三叉神経切断モデルラットの三叉神経脊髄路核尾側亜核および上部頸髄ニューロンにおけるERKのリン酸化 (2010)
  • Author(s): 人見涼露,鈴木郁子,篠田雅路,近藤真哲,岩田幸一
  • Organizer: 第生理87回日本生理学会大会
  • Place of Presentation: 盛岡市民文化ホール,岩手
  • Year and Date: 2010-05-21
• [Presentation] 三叉神経切断モデルラットの三叉神経脊髄路核尾側亜核および上部頸髄ニューロンにおけるERKのリン酸化 (2010)
  • Author(s): 人見涼露
  • Organizer: 第87回日本生理学会
  • Place of Presentation: 盛岡市民文化ホール(宮城)
  • Year and Date: 2010-05-21
• [Presentation] 損傷下歯槽神経再生過程に発症する異所性痛覚過敏の神経メカニズム (2010)
  • Author(s): 人見涼露
  • Organizer: 学術フロンティア研究報告会
  • Place of Presentation: 日本大学,東京
  • Year and Date: 2010-02-19
• [Presentation] 損傷下歯槽神経再生過程に発症する異所性痛覚過敏の神経メカニズム (2010)
  • Author(s): 人見涼露
  • Organizer: 学術フロンティア研究報告会
  • Place of Presentation: 日本大学(東京都)
  • Year and Date: 2010-02-19
• [Presentation] Mitogen activated protein kinase involvement in secondary hyperalgesia during the inferior alveolar nerve regeneration (2009)
  • Author(s): Hitomi S, Saito-Abe K, Suzuki I., Iwata K
  • Organizer: 第39回Society of Neuroscience
  • Place of Presentation: Chicago,USA
  • Year and Date: 2009-10-18
• [Presentation] 損傷下歯槽神経再生過程において顔面領域に発症する異常疼痛の神経機構 (2009)
  • Author(s): 人見涼露
  • Organizer: 第51回歯科基礎医学会
  • Place of Presentation: 朱鷺メッセ(新潟県)
  • Year and Date: 2009-09-10
• [Presentation] 損傷下歯槽神経再生過程において顔面領域に発症する異常疼痛の神経機構 (2009)
  • Author(s): 人見涼露,阿部仁子,岩田幸一
  • Organizer: 第51回歯科基礎医学会
  • Place of Presentation: 朱鷺メッセ,新潟
  • Year and Date: 2009-09-09