Project/Area Number |
21890293
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
General medical chemistry
|
Research Institution | Fukuoka University |
Principal Investigator |
KODAMA Shohta Fukuoka University, 医学部, 准教授 (90549338)
|
Co-Investigator(Renkei-kenkyūsha) |
NISHINAKAMURA Hitomi 福岡大学, グローバルFUプログラム, 研究員 (90597692)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥2,652,000 (Direct Cost: ¥2,040,000、Indirect Cost: ¥612,000)
Fiscal Year 2010: ¥1,261,000 (Direct Cost: ¥970,000、Indirect Cost: ¥291,000)
Fiscal Year 2009: ¥1,391,000 (Direct Cost: ¥1,070,000、Indirect Cost: ¥321,000)
|
Keywords | 再生 / 幹細胞 / 組織工学 / 膵島細胞 / 膵島移植 / 移植・再生医療 / 再生医学 / 糖尿病 / 発生・分化 / 細胞・組織 / 幹細胞研究 |
Research Abstract |
Pancreatic stem cells were identified as the size restricted cells that were harbored in spleen. In addition, the size restricted small cells retained a homology between pancreas and spleen. Furthermore, the cells that were candidate for pancreatic stem cells were up-regulated the expression of critical genes, including Oct3/4, Sox2, c-Myc, Klf4 and Nanog, which were well-known genes as reprogramming for iPS cells.
|