Project/Area Number |
21F20039
|
Research Category |
Grant-in-Aid for JSPS Fellows
|
Allocation Type | Single-year Grants |
Section | 外国 |
Review Section |
Basic Section 36010:Inorganic compounds and inorganic materials chemistry-related
|
Research Institution | National Institute for Materials Science |
Principal Investigator |
山内 悠輔 国立研究開発法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, MANA主任研究者 (10455272)
|
Co-Investigator(Kenkyū-buntansha) |
MASUD MOSTAFA KAMAL 国立研究開発法人物質・材料研究機構, その他部局等, 外国人特別研究員
|
Project Period (FY) |
2021-09-28 – 2023-03-31
|
Project Status |
Declined (Fiscal Year 2022)
|
Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2022: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2021: ¥1,200,000 (Direct Cost: ¥1,200,000)
|
Keywords | 多孔体 |
Outline of Research at the Start |
The overall purpose of this project will be to design and develop nanoarchitectured based inexpensive, and simple biosensing platforms capable of efficiently detecting a range of crucial cancer-related RNA biomarkers in clinical samples, automated diagnostic device fabrication, and in-depth clinical validation of diagnostic device.
|
Outline of Annual Research Achievements |
The goal of this project was to develop an inexpensive, portable and automated system for rapid disease diagnosis by using novel metal nanoarchitectures. These projects are: a. Hydrogel integrated mesoporous gold chronocoulometric sensor for ultrasensitive detection of miRNA. - We fabricated mesoporous gold and integrated it with the hydrogel chemistry to harness the best intrinsic activity from the system to apply for microRNA sensing. The developed sensor provided a much easy, reusable, and highly sensitive microRNA sensor. b. Nanoarchitectured superparamagnetic iron oxide-doped mesoporous carbon nanozymes for biosensing. - We developed a superparamagnetic nano-enzyme that showed high potentiality for magnetic isolation and purification as well as nano-enzyme activity.
|
Research Progress Status |
翌年度、交付申請を辞退するため、記入しない。
|
Strategy for Future Research Activity |
翌年度、交付申請を辞退するため、記入しない。
|