| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2023: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2022: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2021: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
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| Outline of Final Research Achievements |
The allosteric effect is the phenomenon whereby the binding of a molecule to a site other than the ligand binding site causes a change in receptor activity. In this study, we examined odor responses of olfactory sensory neurons and found that odorant receptors exhibit allosteric effects. In addition, we demonstrated that the allosteric effect actually occurs at the level of the odorant receptor with in vitro reconstitution assays.
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