| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2023: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2022: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2021: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
Cell competition is a context-dependent cell elimination whereby cells with higher fitness eliminate neighboring viable, less-fit cells by inducing apoptosis. In this study, we performed a large-scale in vivo screen to identify regulators of a novel type of tumor-suppressive cell competition, and identified several key regulators of it. We also found that a variety of cell competition could be regulated by small number of key regulators.
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