| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2023: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2022: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2021: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
This study raises the possibility that overproduction of QUIN, accompanied by increased expression of IDO1 in brain microglia, is the bona-fide cause of death in sepsis. Future research on sepsis from the viewpoint of senso-immunology, redefining sepsis as a "metabolic disorder of the brain",may lead to the development of innovative and life-saving methods for sepsis.
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