| Project/Area Number |
21K04758
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 27010:Transport phenomena and unit operations-related
|
|---|
| Research Institution | Fukuoka University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
相田 卓 福岡大学, 工学部, 助教 (00466541)
三島 健司 福岡大学, 工学部, 教授 (40190623)
佐藤 朝光 福岡大学, 薬学部, 教授 (90369025)
|
|---|
| Project Period (FY) |
2021-04-01 – 2024-03-31
|
| Project Status |
Completed (Fiscal Year 2023)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2023: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2022: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2021: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | supercritical CO2 / JHA / Pyriproxyfen / microencapsulation / control release / two-phase separation / Phase seperation / carbon dioxide / Protein microparticles / supercritical fluids / hormone analogues / microparticles / mosquito-borne diseases |
|---|
| Outline of Research at the Start |
In this study we introduce highly advance technology of supercritical carbon dioxide (ScCO2) to manufacture Juvenile hormone analogues (JHAs) microcapsules which will be very light to float and enable releasing effective doses just at the place of need. Parameters like pressure (8~14MPa) and temperature (313~343K), polymer ratio, and antisolvent to solvent ratio will be varied to adjust the output. To ensure their controlled release for a longer time, JHAs will be encapsulated with a biodegradable polymer. Evaluation of the encapsulated JHAs particles in Aedes vectors will be carried out.
|
| Outline of Final Research Achievements |
My research on the development of supercritical carbon dioxide-mediated microparticles of juvenile hormone analogues (JHAs) methods has made significant contributions to the field of insect pest management, green chemistry, and agricultural sustainability. Our research findings were presented at 4 national and international conferences and engaged with peers, and experts to disseminate the knowledge and receive feedback on the research. Presentation in the ASCON-IEEChE 2023 KOREA (2023, 12), ICSST23, Okinawa 2023,11, 化学工学会 第53回秋季大会 (2022, 9) and in the ICCCI (2022,11) were highly evaluated. Two articles were published in the Journal of Wiley : Asia-Pacific J. of Chem. Eng.(https://doi.org/10.1002/apj.3043). And, in the J. of the Ins. of Ind. App. Eng. (10.12792/JIIAE.10.60).
|
| Academic Significance and Societal Importance of the Research Achievements |
JHAのscCO2媒介微粒子に関する私の研究は、薬剤製剤に持続可能な溶媒を使用することでグリーンケミストリーを発展させるものです。粒子工学を革新し、JHAの性能とバイオアベイラビリティを最適化することで、効果的な害虫駆除を実現します。社会的には、化学汚染を減らすことで環境の持続可能性を促進し、経済的に実行可能で安全な農法をサポートします。これにより、食品の安全性、消費者の信頼、そして人々の健康を向上させ、世界的な持続可能性の目標に沿うとともに、持続可能な農業に対する人々の意識を高めています。
|
