Project/Area Number |
21K05017
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Review Section |
Basic Section 33010:Structural organic chemistry and physical organic chemistry-related
|
Research Institution | University of Tsukuba |
Principal Investigator |
Lee Vladimir 筑波大学, 数理物質系, 講師 (90375410)
|
Project Period (FY) |
2021-04-01 – 2024-03-31
|
Project Status |
Granted (Fiscal Year 2022)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2023: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | cluster / silicon / pyramidane / germanium / cyclobutadiene dianion / calculations / X-ray crystallography / group 14 element / Frustrated Lewis Pair / Cluster / Inverted carbon atom / Pyramidane / Small molecules |
Outline of Research at the Start |
In this research, we are planning to prepare first representatives of a new highly attractive class of organic compounds, pyramidanes C[C4R4], that have never been synthesized before. Such novel cluster compounds are of particular importance from both fundamental and applied points of view.
|
Outline of Annual Research Achievements |
In this project we aim to synthesize a new class of clusters, pyramidanes, and study their reactivity. During the second year, we discovered unprecedented reactivity of pyramidanes towards organolithium reagents, forming Ge-anionic bicyclopentene derivatives, which can be functionalized to form cyclic and polycyclic compounds.
|
Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The research plans of the second year of the project were realized, in accord with the original plans. Several pyramidanes were synthesized, and their specific reactivity was systematically studied. Particularly important was the interaction of pyramidanes with nucleophilic reagents, such as organolithium compounds, to form a series of unprecedented Ge-anionic bicyclo[2.1.0]pentene derivatives. Thus, during the second year, the project was proceeding smoothly with no troubles and in accord with the proposed plan.
|
Strategy for Future Research Activity |
In the third year of the project, we are going to expand the range of novel pyramidanes, including all-carbon and all-silicon derivatives, applying different synthetic approaches to achieve these goals. All novel compounds will be fully structurally characterized and computationally studied, and their specific reactivity will be thoroughly studied.
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