| Project/Area Number |
21K05017
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 33010:Structural organic chemistry and physical organic chemistry-related
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| Research Institution | University of Tsukuba |
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Principal Investigator |
LEE Vladimir 筑波大学, 数理物質系, 講師 (90375410)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2023: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | cluster / calculations / cyclobutadiene dianion / germanium / group 14 element / organolithium compounds / pyramidane / X-ray diffraction / silicon / X-ray crystallography / germole / Frustrated Lewis Pair / Cluster / Inverted carbon atom / Pyramidane / Small molecules |
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| Outline of Research at the Start |
In this research, we are planning to prepare first representatives of a new highly attractive class of organic compounds, pyramidanes C[C4R4], that have never been synthesized before. Such novel cluster compounds are of particular importance from both fundamental and applied points of view.
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| Outline of Final Research Achievements |
We comprehensively investigated reactivity of the novel Main Group element polyhedral clusters, pyramidanes, towards a range of nucleophilic reagents, first of all, organolithium reagents. In these reactions, pyramidanes revealed an unprecedented electrophilic behavior, which allowed for the smooth approach to a variety of organometallic derivatives featuring E-Li (E = Ge, Sn) bonding. The latter compounds can be readily functionalized with appropriate electrophiles, forming a series of synthetically useful metallole derivatives.
Based on this (and previous) research, we made general conclusions regarding the reaction pathways and mechanisms in the reaction of the cyclobutadiene dianion derivative with the Main Group element halides.
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| Academic Significance and Societal Importance of the Research Achievements |
The developed strategy allows for a synthetic approach towards organometallic compounds featuring E-Li bond (E = Ge, Sn), from which a variety of germole derivatives can be prepared. The latter compounds are important as prospective ligands for transition metal complexes for advanced materials.
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