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Elucidation of accumulation mechanism of cellulose nanofibers at oil-in-water emulsion interface and its application for the production of a novel hollow nanoparticles

Research Project

Project/Area Number 21K05175
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 35010:Polymer chemistry-related
Research InstitutionTomakomai National College of Technology

Principal Investigator

Kono Hiroyuki  苫小牧工業高等専門学校, 創造工学科, 教授 (70455096)

Co-Investigator(Kenkyū-buntansha) 田島 健次  北海道大学, 工学研究院, 准教授 (00271643)
Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2022: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsセルロ―ス / ナノ繊維材料 / 高分子化学 / 構造機能相関 / 微生物セルロース / 複合材料 / 乳化 / エマルション / シランカップリング剤 / ナノフィブリル化セルロース / バクテリアセルロース / ピッカリング乳化 / セルロースナノファイバー / 中空粒子 / 界面集合
Outline of Research at the Start

セルロースナノファイバーによるピッカリング乳化機構の解明と乳化現象を活用した新しい概念に基づく新規中空ナノ粒子の合成を目的とする。エマルジョン形成に伴うNFBC集合状態、ミセル粒径と安定化制御に関する新知見を取得し、中空ナノ粒子の構造設計にフィードバックすることで構造最適化を図る。製剤・樹脂との複合化による特性評価を通じ、その有用性を実証し、ナノ繊維ネットワークが作る多孔性ナノ粒子を創製する。

Outline of Final Research Achievements

Pickering emulsions,” in which solid particles adsorb on the oil-water interface and stabilize droplets by lowering the interfacial tension, are attracting attention as a surfactant-free emulsification system. In this study, we investigated the Pickering emulsification conditions of nanofibrillated bacterial cellulose (NFBC), a high-aspect-ratio nanofiber produced by microorganisms, and the state of accumulation at the micelle interface to clarify the emulsification mechanism by NFBC. In addition, we investigated the composite with resin and proved the effectiveness of nanocomposites as “lightweight, heat-insulating, and low-refractive-index nanofiller”. These results established a new approach to synthesize polysaccharide nanomaterials and contributed to the development of nanomaterials science as a new fundamental technology.

Academic Significance and Societal Importance of the Research Achievements

バイオマス資源、天然糖質の1種であるセルロースを、その構造的特長を活かすことにより乳化剤特性を引き出し、新たな機能性を付与することが可能となった。さらに表層を化学的改質することによって樹脂との複合化を達成し、樹脂の軽量化と高強度化を同時に可能とした。本研究成果は学術的な価値に加え、サステナブルな社会形成に貢献する可能性を含んでいる。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (45 results)

All 2024 2023 2022 2021 Other

All Journal Article (15 results) (of which Peer Reviewed: 11 results,  Open Access: 8 results) Presentation (20 results) (of which Int'l Joint Research: 6 results,  Invited: 2 results) Book (9 results) Remarks (1 results)

  • [Journal Article] Fabrication and characterization of bacterial cellulose/κ-carrageenan composite sheets2024

    • Author(s)
      Numata Yukari、Yamada Chihiro、Kishimoto Ryota、Kono Hiroyuki
    • Journal Title

      Cellulose

      Volume: in press Issue: 9 Pages: 5623-5634

    • DOI

      10.1007/s10570-024-05868-y

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of carboxymethylated Aureobasidium pullulans β-(1→3, 1→6)-glucan and its in vitro antioxidant activity2023

    • Author(s)
      Kono Hiroyuki、Hara Hideyuki、Iijima Kokoro、Fujita Sayaka、Kondo Nobuhiro、Hirabayashi Katsuki、Isono Takuya、Ogata Makoto
    • Journal Title

      Carbohydrate Polymers

      Volume: 322 Pages: 121357-121357

    • DOI

      10.1016/j.carbpol.2023.121357

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chitosan Hydrogels Crosslinked with Oxidized Sucrose for Antimicrobial Applications2023

    • Author(s)
      Fujita Sayaka、Takeda Hijiri、Noda Junki、Wakamori Haruki、Kono Hiroyuki
    • Journal Title

      Gels

      Volume: 9 Issue: 10 Pages: 786-786

    • DOI

      10.3390/gels9100786

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 北海道・東北支部発祥のバクテリアセルロース研究の歩み2023

    • Author(s)
      田島健次、甲野裕之、沼田ゆかり
    • Journal Title

      セルロ―スコミュニケーションズ

      Volume: 30 Pages: 185-196

    • Related Report
      2023 Annual Research Report
  • [Journal Article] キトサンとその誘導体のヒドロゲル化~酸化スクロースを用いた全糖質からなるヒドロゲルの合成2023

    • Author(s)
      甲野 裕之
    • Journal Title

      Glycoforum

      Volume: 26

    • Related Report
      2022 Research-status Report
    • Open Access
  • [Journal Article] Bacterial Cellulose Nanofibers Modified with Quaternary Ammonium Salts for Antimicrobial Applications2023

    • Author(s)
      Kono Hiroyuki、Sogame Yoichiro、Purevdorj Uugan-Erdene、Ogata Makoto、Tajima Kenji
    • Journal Title

      ACS Applied Nano Materials

      Volume: 6 Issue: 6 Pages: 4854-4863

    • DOI

      10.1021/acsanm.3c00616

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Characterization of crab-eating monkey acidic chitinase: Robust chitinolytic activity and its application2022

    • Author(s)
      Hiroyuki Kono
    • Journal Title

      Glycoforum

      Volume: 25 Issue: 6 Pages: A16

    • DOI

      10.32285/glycoforum.25A16

    • ISSN
      1349-9416
    • Year and Date
      2022-12-01
    • Related Report
      2022 Research-status Report
    • Open Access
  • [Journal Article] BIO REVIEW:微生物セルロースナノファイバーの表面改質と繊維強化樹脂への応用2022

    • Author(s)
      甲野裕之
    • Journal Title

      月間BIOINDUSTRY

      Volume: 39(7) Pages: 18-27

    • Related Report
      2022 Research-status Report
  • [Journal Article] Detailed Structural Characterization of Oxidized Sucrose and Its Application in the Fully Carbohydrate-Based Preparation of a Hydrogel from Carboxymethyl Chitosan2022

    • Author(s)
      Kono Hiroyuki、Noda Junki、Wakamori Haruki
    • Journal Title

      Molecules

      Volume: 27 Issue: 18 Pages: 6137-6137

    • DOI

      10.3390/molecules27186137

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Preparation and Enzyme Degradability of Spherical and Water-Absorbent Gels from Sodium Carboxymethyl Cellulose2022

    • Author(s)
      Fujita Sayaka、Tazawa Toshiaki、Kono Hiroyuki
    • Journal Title

      Gels

      Volume: 8 Issue: 5 Pages: 321-321

    • DOI

      10.3390/gels8050321

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 核磁気共鳴スペクトルによる多糖類の構造化学的研究2022

    • Author(s)
      甲野裕之
    • Journal Title

      キチン・キトサン研究 Chitin and Chitosan Research

      Volume: 28 Pages: 22-32

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reinforcing Poly(methyl methacrylate) with Bacterial Cellulose Nanofibers Chemically Modified with Methacryolyl Groups2022

    • Author(s)
      Kono Hiroyuki、Tsujisaki Haruto、Tajima Kenji
    • Journal Title

      Nanomaterials

      Volume: 12 Issue: 3 Pages: 537-537

    • DOI

      10.3390/nano12030537

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 核磁気共鳴スペクトルによる多糖類の構造化学的研究2022

    • Author(s)
      甲野裕之
    • Journal Title

      キチン・キトサン研究

      Volume: 28 Pages: 22-32

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Facile Post-Carboxymethylation of Cellulose Nanofiber Surfaces for Enhanced Water Dispersibility2021

    • Author(s)
      Kono Hiroyuki、Tsukamoto Eiki、Tajima Kenji
    • Journal Title

      ACS Omega

      Volume: 6 Issue: 49 Pages: 34107-34114

    • DOI

      10.1021/acsomega.1c05603

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Elucidation of substituent distribution states for carboxymethyl chitosan by detailed NMR analysis2021

    • Author(s)
      Kono Hiroyuki、Kato Taisetsu
    • Journal Title

      Carbohydrate Polymer Technologies and Applications

      Volume: 2 Pages: 100175-100175

    • DOI

      10.1016/j.carpta.2021.100175

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 表面修飾した微生物由来セルロースナノファイバーの樹脂に対する物性改良効果2024

    • Author(s)
      瀬野修一郎, 可児浩, 細川真明, Hamidah binti Hashim, Nur Aisyah Adlin binti E, 二之湯寛子, 辻崎晴人, 夏小超, 磯野拓也, 山本拓矢, 佐藤敏文, 折原宏, 甲野裕之, 田島健次
    • Organizer
      産総研北海道センターシンポジウムin札幌
    • Related Report
      2023 Annual Research Report
  • [Presentation] 表層変性ナノフィブリル化バクテリアセルロースによる生分解性樹脂の高強度化2024

    • Author(s)
      横川愛莉, 高谷賢乃介, 瀬野修一郎, 田島健次, 甲野裕之
    • Organizer
      第58回高分子学会北海道支部研究発表会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Emulsification by carbohydrates and its emulsification mechanism2023

    • Author(s)
      Hibiki Yamashita, Muneaki Tomotake, Baku Onishi, Sayaka Fujita, Makoto Ogata, Hiroyuki Kono
    • Organizer
      The 13th SPSJ International Polymer Conference (IPC2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] EDTA表層改質セルロースナノファイバーの金属吸着特性2023

    • Author(s)
      佐々涼水, 木下七海, 岸本亮太, 藤田彩華, 甲野裕之, 田島健次
    • Organizer
      2023年度 北海道高分子若手研究会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 水溶性多糖とシクロデキストリンによる乳化作用とその特性解析2023

    • Author(s)
      山下響生, 朝武宗明, 大西漠, 尾形慎, 甲野裕之
    • Organizer
      日本応用糖質科学会2023年度大会(第72回)
    • Related Report
      2023 Annual Research Report
  • [Presentation] 微生物由来セルロースナノファイバーの表面修飾が樹脂の物性改良効果に与える影響2023

    • Author(s)
      瀬野 修一郎, 可児 浩, 細川 真明, binti Hashim Hamida, binti Emran Nur Aisyah Adlin, 勝原 哲, 二之湯 寛子, 辻崎 晴人, 夏 小超, 磯野 拓也, 山本 拓也, 佐藤 敏文, 折原 宏, 田島 健次, 甲野 裕之
    • Organizer
      第72回高分子討論会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Preparation of bacterial cellulose/κ-carrageenan composite sheets from two-layer-structured pellicle2023

    • Author(s)
      Yukari Numata, Chihiro Yamada, Hiroyuki Kono
    • Organizer
      The 5th International Cellulose Conference (ICC 2022+1)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation and antimicrobial activity of nanofibrillated bacterial cellulose surface modified with quaternary ammonium salts2023

    • Author(s)
      Hiroyuki Kono, Yoichiro Sogame, Uugan-Erdene Purevdorj, Makoto Ogata, Kenji Tajima
    • Organizer
      The 5th International Cellulose Conference (ICC 2022+1)
    • Related Report
      2023 Annual Research Report 2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 表層変性NFBCと生分解性樹脂の複合化とその機械的特性評価2023

    • Author(s)
      横川愛莉, 玉川璃桜, 髙谷賢乃介, 岸本亮太, 甲野裕之, 瀬野修一郎, 田島健次
    • Organizer
      セルロース学会第30回年次大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Emulsification by carbohydrates and its emulsification mechanism2023

    • Author(s)
      Hibiki Yamashita, Muneaki Tomotake, Baku Onishi, Sayaka Fujita, Makoto Ogata, Hiroyuki Kono
    • Organizer
      The 13th SPSJ International Polymer Conference (IPS2013)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Preparation of glycan-immobilized nanogel particles and their selective interaction with lectins2023

    • Author(s)
      Hiroyuki Kono, Remi Anazawa, Lisa Conolly, Mitsuki Asano, Ryota Kishimoto, Makoto Ogata
    • Organizer
      The 13th SPSJ International Polymer Conference (IPS2013)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 酸化ショ糖の高分子架橋剤への応用2023

    • Author(s)
      甲野裕之, 若森春輝, 野田純希
    • Organizer
      令和4年度日本応用糖質科学会北海道支部講演会
    • Related Report
      2022 Research-status Report
  • [Presentation] 糖質乳化~乳化機構の解明と天然乳化剤の開発~2023

    • Author(s)
      山下響生, 大西漠, 古瀬吏玖, 藤田彩華, 尾形慎, 甲野裕之
    • Organizer
      第57回高分子学会北海道支部研究発表会
    • Related Report
      2022 Research-status Report
  • [Presentation] セルロース誘導体を基材とした球状吸水性ゲルの合成と粒径制御2022

    • Author(s)
      藤田 彩華, 田澤 寿明, 甲野 裕之
    • Organizer
      第71回高分子討論会
    • Related Report
      2022 Research-status Report
  • [Presentation] EDTA グラフト化セルロースナノファイバーの金属吸着性評価2022

    • Author(s)
      佐々凉水, 木下七海, 岸本亮太, 藤田彩華, 甲野裕之, 田島健次
    • Organizer
      2022年度 北海道高分子若手研究会
    • Related Report
      2022 Research-status Report
  • [Presentation] ナノフィブリル化微生物セルロースの表面化学修飾と樹脂との相互作用に関する研究2022

    • Author(s)
      甲野裕之, 辻崎晴人, 宇野大輝, 田島健次
    • Organizer
      セルロース学会第29回年次大会
    • Related Report
      2022 Research-status Report
  • [Presentation] ナノフィブリル化微生物セルロース表面の選択的カルボキシメチル化に関する研究2022

    • Author(s)
      甲野裕之, 塚本英樹, 田島健次
    • Organizer
      セルロース学会第29回年次大会
    • Related Report
      2022 Research-status Report
  • [Presentation] シランカップリング剤によるナノフィブリル化微生物セルロースの表層疎水処理と樹脂との複合化2021

    • Author(s)
      辻崎晴人, 宇野大輝, 岸本亮太, 甲野裕之, 松島徳雄, 田島健次
    • Organizer
      セルロース学会第28回年次大会
    • Related Report
      2021 Research-status Report
  • [Presentation] Surface modification of cellulose nanofiber using silane coupling agent for poly(methyl methacrylate) reinforcement2021

    • Author(s)
      Hiroyuki Kono
    • Organizer
      The 21st Chitose International Forum of Science and Technology
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 表層疎水化微生物セルロースナノファイバーによる樹脂の高強度化2021

    • Author(s)
      甲野裕之
    • Organizer
      令和3年度 JST新技術説明会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Book] 環境配慮型材料技術トレンドレポート vol.72023

    • Author(s)
      甲野裕之ら
    • Total Pages
      92
    • Publisher
      AndTech
    • ISBN
      9784909118639
    • Related Report
      2023 Annual Research Report
  • [Book] 環境配慮を考えた紙おむつ材料の最新開発動向とリサイクルシステムの課題・今後の期待 ~生分解性を持つ高吸水性樹脂・植物由来バイオプラスチック・おむつリサイクルの現状~2023

    • Author(s)
      甲野裕之、和田充弘
    • Total Pages
      50
    • Publisher
      株式会社AndTech
    • Related Report
      2023 Annual Research Report
  • [Book] Advances in Cellulose-Based Hydrogels2023

    • Author(s)
      Sayaka Fujita, Toshiaki Tazawa, Hiroyuki Kono
    • Total Pages
      276
    • Publisher
      MDPI Basel
    • ISBN
      9783036571119
    • Related Report
      2023 Annual Research Report
  • [Book] Proceedings of 21st Chitose International Forum on Science and Technology (Pages 4-9, Preparation and characterization of a novel chitosan-based hydrogel using sucrose as a cross-linking agent)2022

    • Author(s)
      Junki Noda, Hiroyuki Kono
    • Total Pages
      100
    • Publisher
      PWC Publishing
    • ISBN
      9784990430184
    • Related Report
      2022 Research-status Report
  • [Book] Proceedings of 21st Chitose International Forum on Science and Technology (Pages 20-24, Surface modification of cellulose nanofiber using silane coupling agent for poly(methyl methacryrate) reinforcement)2022

    • Author(s)
      Hiroyuki Kono
    • Total Pages
      100
    • Publisher
      PWC Publishing
    • ISBN
      9784990430184
    • Related Report
      2022 Research-status Report
  • [Book] Proceedings Chitose International forum 212022

    • Author(s)
      Hiroyuki Kono
    • Publisher
      Chitose Institute of Science and Technology
    • Related Report
      2021 Research-status Report
  • [Book] セルロースナノファイバー 研究と実用化の最前線2021

    • Author(s)
      矢野 浩之、磯貝 明、北川 和男
    • Total Pages
      896
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437510
    • Related Report
      2021 Research-status Report
  • [Book] NMRによる有機材料分析とその試料前処理、データ解釈2021

    • Author(s)
      執筆者:59名、技術情報協会
    • Total Pages
      676
    • Publisher
      技術情報協会
    • ISBN
      9784861048609
    • Related Report
      2021 Research-status Report
  • [Book] 【水】と機能性ポリマーに関する材料設計,最新応用2021

    • Author(s)
      執筆者:63名、エヌ・ティー・エス
    • Total Pages
      927
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784861048531
    • Related Report
      2021 Research-status Report
  • [Remarks] 国際会議招待講演のProceedings (I-4)

    • URL

      https://www.chitose.ac.jp/cif

    • Related Report
      2021 Research-status Report

URL: 

Published: 2021-04-28   Modified: 2025-01-30  

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