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Neuroendocrinological mechanisms for life-long monogamy in syngnathid fishes.

Research Project

Project/Area Number 21K06261
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
Research InstitutionHirosaki University

Principal Investigator

Sogabe Atsushi  弘前大学, 農学生命科学部, 准教授 (80512714)

Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2022: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords配偶システム / 魚類 / 遺伝子発現解析 / ペアボンド / 一夫一妻 / バソトシン / RNA-Seq / ヨウジウオ科
Outline of Research at the Start

一夫一妻の動物におけるペアボンド維持の至近的機構として、神経内分泌の働きが注目されている。様々な動物で研究が進められているが、哺乳類から魚類まで脊椎動物に広く認められる一夫一妻が、共通した神経内分泌基盤により成り立っているのか、個々に独立した進化的背景を有するのかは未解決の問題である。本研究では、他に類をみないほど安定した一夫一妻を維持することが知られているヨウジウオ科魚類をモデルとして、一夫一妻維持の至近的機構とその遺伝基盤を解明する。

Outline of Final Research Achievements

The purpose of this study is to comprehensively elucidate the neuroendocrine mechanisms that function in maintenance of pair bond in monogamous syngnathid fishes. We used three approaches to accomplish the purpose: 1)the analysis of gene expression in the brain that change their expression levels in response to the behavior important for the maintenance of pair bonds in the life-long monogamous pipefish, 2) comparative transcriptome analysis of four species of syngnathids with different mating systems, and 3) analysis of the vasotocin receptor gene, which is known to be a putative gene for the determination of mating system in voles. Although it was unable to proceed with the research as originally planned due to the new corona disaster, I was able to obtain a number of gene expression profiles that will serve as the basis for future research.

Academic Significance and Societal Importance of the Research Achievements

多様な配偶システムを示すヨウジウオ科魚類は、北欧を中心にアメリカ、オーストラリアなど海外で盛んに研究されてきた。しかし、これまでの研究は配偶システム決定の究極要因の解明を目指したものであり、配偶システム変異を至近的機構の面から研究した例はほとんどない。ペアボンド維持の至近的機構とその遺伝基盤については、ハタネズミ類を中心にヒトを含む哺乳類で盛んに行われてきたが、魚類や鳥類など広範な分類群にみられる一夫一妻のペアボンド維持機構に系統を超えた普遍性があるのか、個々に独立した進化的起源があるのかは未解決の問題であり、ヨウジウオ科魚類を対象にした本研究はその一端を明らかにするものである。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (13 results)

All 2023 2022 2021

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 4 results) Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Spatial epidemiology model can explain the seasonal dynamics of infectious disease Cyprinid herpesvirus 3 (CyHV-3) by thermoregulation behavior of the host, common carp (Cyprinus carpio)2023

    • Author(s)
      Miki Takeshi、Yamanaka Hiroki、Sogabe Atsushi、Omori Koji、Saito Yasuhisa、Minamoto Toshifumi、Uchii Kimiko、Honjo Mie N.、Suzuki Alata A.、Kohmatsu Yukihiro、Kawabata Zen’ichiro
    • Journal Title

      Theoretical Ecology

      Volume: 16 Issue: 3 Pages: 195-208

    • DOI

      10.1007/s12080-023-00563-3

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Orphan gene expressed in flame cone cells uniquely found in seahorse epithelium2023

    • Author(s)
      Kawaguchi Mari、Chang Wen-Shan、Tsuchiya Hazuki、Kinoshita Nana、Miyaji Akira、Kawahara-Miki Ryouka、Tomita Kenji、Sogabe Atsushi、Yorifuji Makiko、Kono Tomohiro、Kaneko Toyoji、Yasumasu Shigeki
    • Journal Title

      Cell and Tissue Research

      Volume: 393 Issue: 1 Pages: 47-62

    • DOI

      10.1007/s00441-023-03779-1

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Habitat preferences, genetic isolation and climatic vulnerability of an endangered freshwater crayfish and a widespread freshwater crab in streams of northern Japan2023

    • Author(s)
      Hinosawa Tsubasa、Kinami Saki、Sogabe Atsushi、Ohtaka Akifumi、Azuma Nobuyuki、Ikeda Hiroshi
    • Journal Title

      Aquatic Conservation: Marine and Freshwater Ecosystems

      Volume: 33 Issue: 7 Pages: 761-772

    • DOI

      10.1002/aqc.3953

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete mitochondrial genome of a subspecies of the great cormorant, <i>Phalacrocorax carbo hanedae</i> (Kuroda, 1925) (Suliformes: Phalacrocoracidae)2023

    • Author(s)
      Honda Rina、Inumaru Mizue、Sato Yukita、Sogabe Atsushi
    • Journal Title

      Mitochondrial DNA Part B

      Volume: 8 Issue: 1 Pages: 61-63

    • DOI

      10.1080/23802359.2022.2160671

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brood pouch evolution in pipefish and seahorse based on histological observation.2022

    • Author(s)
      Akari Harada, Ryotaro Shiota, Ryohei Okubo, Makiko Yorifuji, Atsushi Sogabe, Hiroyuki, Motomura, Junya Hiroi, Shigeki Yasumasu, and Mari Kawaguchi
    • Journal Title

      Placenta

      Volume: 120 Pages: 88-96

    • DOI

      10.1016/j.placenta.2022.02.014

    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Complete mitochondrial genome of the Japanese Cormorant <i>Phalacrocorax capillatus</i> (Temminck &amp; Schlegel, 1850) (Suliformes: Phalacrocoracidae)2022

    • Author(s)
      Honda Rina、Inumaru Mizue、Sato Yukita、Sogabe Atsushi
    • Journal Title

      Mitochondrial DNA Part B

      Volume: 7 Issue: 8 Pages: 1577-1578

    • DOI

      10.1080/23802359.2022.2113753

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Complete mitochondrial genome of the Japanese field vole <i>microtus montebelli</i> (Milne-Edwards, 1872) (Rodentia: Arvicolinae)2021

    • Author(s)
      Sogabe Atsushi、Murano Chie、Morii Ryota、Ikeda Hiroshi、Hata Hiroki
    • Journal Title

      Mitochondrial DNA Part B

      Volume: 6 Issue: 9 Pages: 2717-2718

    • DOI

      10.1080/23802359.2021.1917315

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Marine-dumped waste tyres cause the ghost fishing of hermit crabs2021

    • Author(s)
      Sogabe Atsushi、Takatsuji Kiichi
    • Journal Title

      Royal Society Open Science

      Volume: 8 Issue: 10 Pages: 2110166-2110166

    • DOI

      10.1098/rsos.210166

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 家畜化メダカと野生メダカの交雑がF1個体の学習能と個性へ及ぼす影響2023

    • Author(s)
      井口日永・上村啄斗・工藤咲希・鳥山菜香・井上和泉・水野直樹・東信行・曽我部篤
    • Organizer
      第57回日本魚類学会年会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 十和田湖に人為導入されたトゲウオ2種の収斂的な形態変化2022

    • Author(s)
      森山翼・森誠一・曽我部篤
    • Organizer
      第55回日本魚類学会年会
    • Related Report
      2022 Research-status Report
  • [Presentation] Loss of vasotocin 1a1R gene in syngnathids2021

    • Author(s)
      Yoshida, R., Sasahira, M., Nishino, J., Nishino, A., Sogabe, A.
    • Organizer
      Syngbio2021
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] ヨウジウオ科魚類におけるバソトシン1a1受容体遺伝子の消失2021

    • Author(s)
      吉田崚馬・笹平素生・西野純子・西野敦雄・曽我部篤
    • Organizer
      日本動物学会第92回大会(オンライン)
    • Related Report
      2021 Research-status Report
  • [Presentation] 耳石Sr/Ca比分析によるクルメサヨリの回遊履歴推定2021

    • Author(s)
      阿部勝徳・鬼倉徳雄・加納光樹・桑原正樹・古屋康則・白井厚太朗・杉山秀樹・東信行・曽我部篤
    • Organizer
      第54回魚類学会年会(オンライン)
    • Related Report
      2021 Research-status Report

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Published: 2021-04-28   Modified: 2025-01-30  

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