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Development of the diagnostic imaging supporting system for the artery of Adamkiewicz

Research Project

Project/Area Number 21K07572
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionIwate Medical University

Principal Investigator

Yoshioka Kunihiro  岩手医科大学, 医学部, 教授 (70210648)

Co-Investigator(Kenkyū-buntansha) 折居 誠  岩手医科大学, 医学部, 講師 (70508986)
Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2021: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsAdamkiewicz動脈 / 大動脈瘤 / CT / エックス線CT / 脊髄
Outline of Research at the Start

胸部下行大動脈瘤の手術において、術後対麻痺は重篤な合併症の一つである。
それを回避するための対策の一つとして、CTを用いたAdamkiewicz動脈の術前診断が推奨されている。
しかし、その診断精度は約50%に過ぎず、その描出や評価には熟練や手間が必要で、これが実臨床で実施する場合の大きな妨げとなっている。
そこで、本研究では人工知能の技術を用いて、Adamkiewicz動脈のCT診断を支援する方法を開発し、もって術後対麻痺の回避に貢献する。

Outline of Final Research Achievements

Diagnosis of the artery of Adamkiewicz, which is important for preoperative evaluation of thoracoabdominal aortic aneurysms, is often challenging even for specialists. Using artificial intelligence (AI) technology, a system has been developed to assist in the diagnosis of the artery from CT images. As a result, the artery of Adamkiewicz could be extracted in 8 out of 15 cases (53%). On the other hand, the artery of Adamkiewicz could not be extracted in 6 cases (40%), and the anterior radiculomedullary vein was misidentified as the artery of Adamkiewicz artery in 1case (7%).
These results confirmed that the artery of Adamkiewicz could be extracted automatically in more than half of the cases in using AI. However, further improvement in accuracy is needed for clinical use.

Academic Significance and Societal Importance of the Research Achievements

AIを用いることで53%の症例でAdamkiewicz動脈を自動抽出できることが判明した。専門医による同動脈の診断精度も50%程度との報告もあるので、これにほぼ匹敵する精度とも言える。今後自動抽出の精度が向上できればAdamkiewicz動脈の術前診断が非専門医でも専門医と同等以上となり、ひいては大動脈瘤術後の対麻痺の回避に貢献することが期待される。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (13 results)

All 2023 2022 2021

All Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 8 results,  Open Access: 6 results) Presentation (2 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Book (3 results)

  • [Journal Article] A Comparison of Retrospective ECG-Gated CT and Surgical or Angiographical Findings in Acute Aortic Syndrome2023

    • Author(s)
      Orii Makoto、Sone Misato、Fujiwara Jumpei、Sasaki Tadashi、Chiba Takuya、Kin Hajime、Morino Yoshihiro、Tanaka Ryoichi、Yoshioka Kunihiro
    • Journal Title

      International Heart Journal

      Volume: 64 Issue: 5 Pages: 839-846

    • DOI

      10.1536/ihj.23-002

    • ISSN
      1349-2365, 1349-3299
    • Year and Date
      2023-09-30
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] JCS/JSCVS/JATS/JSVS 2020 Guideline on Diagnosis and Treatment of Aortic Aneurysm and Aortic Dissection2023

    • Author(s)
      Ogino Hitoshi、Iida Osamu、Akutsu Koichi、、Ueda Tatsuo、et al. on behalf of the Japanese Circulation Society, the Japanese Society for Cardiovascular Surgery, the Japanese Association for Thoracic Surgery and the Japanese Society for Vascular Surgery Joint Working Group
    • Journal Title

      Circulation Journal

      Volume: 87 Issue: 10 Pages: 1410-1621

    • DOI

      10.1253/circj.CJ-22-0794

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2023-09-25
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recent Innovation of CT Imaging in Vascular Diseases2023

    • Author(s)
      Yoshioka Kunihiro、Orii Makoto、Tanaka Ryoich
    • Journal Title

      The Journal of Japanese College of Angiology

      Volume: 63 Issue: 4 Pages: 39-43

    • DOI

      10.7133/jca.23-00008

    • ISSN
      0387-1126, 1880-8840
    • Year and Date
      2023-07-10
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Super-resolution deep learning reconstruction at coronary computed tomography angiography to evaluate the coronary arteries and in-stent lumen: an initial experience2023

    • Author(s)
      Orii Makoto、Sone Misato、Osaki Takeshi、Ueyama Yuta、Chiba Takuya、Sasaki Tadashi、Yoshioka Kunihiro
    • Journal Title

      BMC Medical Imaging

      Volume: 23 Issue: 1 Pages: 171-171

    • DOI

      10.1186/s12880-023-01139-7

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Aortic Elongation in Bicuspid Aortic Valve with Aortic Stenosis Assessed by Thin-Slice Electrocardiogram-Gated Computed Tomography2022

    • Author(s)
      Fujiwara Jumpei、Orii Makoto、Takagi Hidenobu、Chiba Takuya、Sasaki Tadashi、Tanaka Ryoichi、Kin Hajime、Morino Yoshihiro、Yoshioka Kunihiro
    • Journal Title

      International Heart Journal

      Volume: 63 Issue: 2 Pages: 319-326

    • DOI

      10.1536/ihj.21-244

    • NAID

      130008161324

    • ISSN
      1349-2365, 1349-3299
    • Year and Date
      2022-03-30
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] CT imaging with ultra-high-resolution: Opportunities for cardiovascular imaging in clinical practice2022

    • Author(s)
      Schuijf Joanne D.、Lima Jo?o A.C.、Boedeker Kirsten L.、Takagi Hidenobu、Tanaka Ryoichi、Yoshioka Kunihiro、Arbab-Zadeh Armin
    • Journal Title

      Journal of Cardiovascular Computed Tomography

      Volume: 16 Issue: 5 Pages: 388-396

    • DOI

      10.1016/j.jcct.2022.02.003

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Thoracoabdominal aortic aneurysm repair based on pre- and postoperative evaluation of the artery of Adamkiewicz2022

    • Author(s)
      Imamura Yuki、Kin Hajime、Yoshioka Kunihiro、Tabayashi Azuma、Saitoh Daiki
    • Journal Title

      European Journal of Cardio-Thoracic Surgery

      Volume: 62 Issue: 5

    • DOI

      10.1093/ejcts/ezac196

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Collateral pathways to the artery of Adamkiewicz2021

    • Author(s)
      Saitoh Daiki、Yoshioka Kunihiro、Kin Hajime
    • Journal Title

      Asian Cardiovascular and Thoracic Annals

      Volume: 29 Issue: 9 Pages: 968-969

    • DOI

      10.1177/02184923211006854

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Presentation] 脈管画像診断の進歩:CTの進歩と脈管画像診断2022

    • Author(s)
      吉岡邦浩
    • Organizer
      第63回日本脈管学会総会
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] Demonstration of collateral pathways to the artery of Adamkiewicz using ultra-high-resolution CT angiography2021

    • Author(s)
      Yoshioka Kunihiro, Orii Makoto, Tanaka Ryoichi
    • Organizer
      107th Scientific Assemgly and Annual Metting of Radiological Society of North America
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Book] CT縦横無尽2023

    • Author(s)
      粟井 和夫、尾田 済太郎、船間 芳憲
    • Total Pages
      552
    • Publisher
      メジカルビュー社
    • ISBN
      9784758321068
    • Related Report
      2023 Annual Research Report
  • [Book] 画像診断ガイドライン 2021年版2021

    • Author(s)
      日本医学放射線学会
    • Total Pages
      552
    • Publisher
      金原出版
    • ISBN
      9784307071239
    • Related Report
      2021 Research-status Report
  • [Book] 心臓・大血管 画像診断の勘ドコロNEO2021

    • Author(s)
      横山 健一
    • Total Pages
      292
    • Publisher
      メジカルビュー社
    • ISBN
      9784758316156
    • Related Report
      2021 Research-status Report

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Published: 2021-04-28   Modified: 2025-01-30  

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