Epidemiological Research on intractable, rare, and incurable ophthalmological diseases using NDB claims data.

• Project/Area Number: 21K09740
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 56060:Ophthalmology-related
• Research Institution: Kyoto University
• Principal Investigator: 田村 寛 京都大学, 国際高等教育院, 教授 (40418760)
• Co-Investigator(Kenkyū-buntansha): 加藤 源太 京都大学, 医学研究科, 准教授 (20571277) ; 平木 秀輔 公益財団法人田附興風会, 医学研究所 保健・健康研究部, 研究主幹 (60781523) ; 三宅 正裕 京都大学, 医学研究科, 特定講師 (90812793) ; 池田 華子 京都大学, 医学研究科, 特定准教授 (20372162) ; 辻川 明孝 京都大学, 医学研究科, 教授 (40402846)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2023: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2022: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2021: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: NDB / 難病 / 希少疾患 / オンサイト / 疫学

Outline of Research at the Start

眼科関連の難病・希少疾患・難治性疾患のRWDに基づくエビデンス創出のために、全国に2か所しかないNDBオンサイトリサーチセンターを活用した疫学研究を行う。これまでに実現が困難であった難病・希少疾患および眼科に特化した対応の必要性を解決するため、最新の疫学・データサイエンスの手法を用いる。本研究の先には、将来の患者数予測や新規治療の開発可能性の拡大、当該領域におけるNDB活用基盤の形成も期待される。

Outline of Annual Research Achievements

本研究では、1.眼科難病・希少疾患および難治性疾患の実態を把握し、その病態解明および治療方法開発へとつながる疫学的知見を得ることと、2.全国民をカバーするＮＤＢを用いて、難病・希少疾患・難治性疾患や眼科の疫学的研究を行う際に残される課題を抽出すること、目指して研究を遂行した。
眼科関連の難病・希少疾患・難治性疾患のReal Worl d Dataに基づくエビデンス創出のために、全国に2か所しかないNDBオンサイトリサーチセンターを活用した疫学研究を行った。
これまでに実現が困難であった難病・希少疾患および眼科に特化した対応の必要性を解決するため、最新の疫学・データサイエンスの手法を用いた。
特に、2023年度は、2021年度と2022年度の経験を活用し、全身性に発症し複数診療科受診がある難病・希少疾患としての眼腫瘍（木戸ら　日本眼腫瘍学会）や、眼科に限局しつつもれぷととじょうの定義に工夫を要した網膜色素変性（木戸ら　網膜硝子体学会）や斜視（宮田ら　京都眼科学会）についても、① 有病率や発症率の調査（性別、年齢別、地域別など） ② 患者背景（ 年齢、性別、併存疾患、使用薬剤など）の把握 ③ 実臨床で施行されている治療内容および治療成績を把握し、その変遷の調査を実施できた。
また、これらの報告の中でも、弾性線維性仮性黄色腫（指定難病166）（Wada S et al. Ophthalmo Sci 2023)と斜視（Miyata M et al. AJO 2024）については英文誌に掲載され、近視ついては英文誌で査読中のところまで進めることができた。特に、斜視の報告ついては、複数のメディアにも取り上げられるなど社会的インパクトの高い成果につなげることができた。

Research Products

• [Journal Article] Epidemiology of Angioid Streaks and Pseudoxanthoma Elasticum (2011?2020) (2024)
  • Author(s): Wada Saori、Miyake Masahiro、Kido Ai、Kamei Takuro、Hiragi Shusuke、Ikeda Hanako Ohashi、Hata Masayuki、Ueshima Hiroaki、Tsujikawa Akitaka、Tamura Hiroshi
  • Journal Title: Ophthalmology Science Volume: 4 Issue: 2 Pages: 100370-100370
  • DOI: 10.1016/j.xops.2023.100370
  • Peer Reviewed / Open Access
• [Journal Article] Macular chorioretinal atrophy and visual outcomes in ranibizumab- or aflibercept-treated myopic choroidal neovascularization (2024)
  • Author(s): Kawashima Yu、Hata Masayuki、Miyake Masahiro、Kusaka Mami、Oishi Akio、Ooto Sotaro、Tamura Hiroshi、Miyata Manabu、Uji Akihito、Ueda-Arakawa Naoko、Takahashi Ayako、Tsujikawa Akitaka
  • Journal Title: Retina Volume: 44 Pages: 127-135
  • DOI: 10.1097/iae.0000000000003930
  • Peer Reviewed
• [Journal Article] Short-Term Outcomes of 3 Monthly intravitreal Faricimab On Different Subtypes of Neovascular Age-Related Macular Degeneration (2024)
  • Author(s): Tanaka Asako、Hata Masayuki、Tsuchikawa Memiri、Ueda-Arakawa Naoko、Tamura Hiroshi、Miyata Manabu、Takahashi Ayako、Kido Ai、Muraoka Yuki、Miyake Masahiro、Ooto Sotaro、Tsujikawa Akitaka
  • Journal Title: Clinical Ophthalmology Volume: 18 Pages: 507-516
  • DOI: 10.2147/opth.s448507
  • Peer Reviewed / Open Access
• [Journal Article] Prevalence and Incidence of Strabismus by Age Group in Japan: A Nationwide Population-Based Cohort Study (2024)
  • Author(s): Miyata Manabu、Kido Ai、Miyake Masahiro、Tamura Hiroshi、Kamei Takuro、Wada Saori、Ueshima Hiroaki、Kawai Kentaro、Nakao Shinya、Yamamoto Akinari、Suda Kenji、Nakano Eri、Tagawa Miho、Tsujikawa Akitaka
  • Journal Title: American Journal of Ophthalmology Volume: 262 Pages: 222-228
  • DOI: 10.1016/j.ajo.2023.11.022
  • Peer Reviewed / Open Access
• [Journal Article] TEN-YEAR VISUAL OUTCOME AND CHANGE IN CHORIORETINAL ATROPHY AFTER INTRAVITREAL RANIBIZUMAB FOR MACULAR NEOVASCULARIZATION IN PATHOLOGIC MYOPIA (2023)
  • Author(s): Sakata Ryo、Miyata Manabu、Ooto Sotaro、Tamura Hiroshi、Ueda-Arakawa Naoko、Muraoka Yuki、Miyake Masahiro、Hata Masayuki、Takahashi Ayako、Kido Ai、Numa Shogo、Mori Yuki、Tsuda Kanae、Uji Akihito、Oishi Akio、Tsujikawa Akitaka
  • Journal Title: Retina Volume: 43 Pages: 1863-1871
  • DOI: 10.1097/iae.0000000000003869
  • Peer Reviewed
• [Journal Article] Extensive reduction in choroidal thickness after photodynamic therapy in eyes with central serous chorioretinopathy (2023)
  • Author(s): Nishigori Naomi、Muraoka Yuki、Ishikura Masaharu、Kogo Takahiro、Ueda-Arakawa Naoko、Miyata Manabu、Tamura Hiroshi、Hata Masayuki、Takahashi Ayako、Miyake Masahiro、Tsujikawa Akitaka
  • Journal Title: Scientific Reports Volume: 13 Issue: 1 Pages: 10890-10890
  • DOI: 10.1038/s41598-023-37802-w
  • Peer Reviewed / Open Access
• [Journal Article] PREDICTORS OF 3-MONTH AND 1-YEAR VISUAL OUTCOMES AFTER VITRECTOMY WITH SUBRETINAL TISSUE PLASMINOGEN ACTIVATOR INJECTION FOR SUBMACULAR HEMORRHAGE (2023)
  • Author(s): Miki Makoto、Miyata Manabu、Ooto Sotaro、Tamura Hiroshi、Ueda-Arakawa Naoko、Muraoka Yuki、Miyake Masahiro、Hata Masayuki、Takahashi Ayako、Kido Ai、Kogo Takahiro、Uji Akihito、Tsujikawa Akitaka
  • Journal Title: Retina Volume: 43 Pages: 1971-1979
  • DOI: 10.1097/iae.0000000000003885
  • Peer Reviewed
• [Journal Article] Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy (2023)
  • Author(s): Kogo Takahiro、Muraoka Yuki、Ishikura Masaharu、Nishigori Naomi、Ueda-Arakawa Naoko、Miyata Manabu、Tamura Hiroshi、Hata Masayuki、Takahashi Ayako、Miyake Masahiro、Tsujikawa Akitaka
  • Journal Title: Heliyon Volume: 9 Issue: 8 Pages: e18441-e18441
  • DOI: 10.1016/j.heliyon.2023.e18441
  • Peer Reviewed / Open Access
• [Journal Article] Annual Trends of Ophthalmic Surgeries in Japan’s Super-aged Society, 2014? 2020: A National Claims Database Study (2023)
  • Author(s): Wada Saori、Miyake Masahiro、Hata Masayuki、Kido Ai、Kamei Takuro、Akada Masahiro、Hiragi Shusuke、Tamura Hiroshi、Tsujikawa Akitaka
  • Journal Title: Scientific Reports Volume: -
  • DOI: 10.21203/rs.3.rs-3480692/v1
  • Peer Reviewed / Open Access
• [Journal Article] Therapeutic effects of faricimab on aflibercept-refractory age-related macular degeneration (2023)
  • Author(s): Tamiya Ryosuke、Hata Masayuki、Tanaka Asako、Tsuchikawa Memiri、Ueda-Arakawa Naoko、Tamura Hiroshi、Miyata Manabu、Takahashi Ayako、Kido Ai、Muraoka Yuki、Miyake Masahiro、Ooto Sotaro、Tsujikawa Akitaka
  • Journal Title: Scientific Reports Volume: 13 Issue: 1 Pages: 21128-21128
  • DOI: 10.1038/s41598-023-48190-6
  • Peer Reviewed / Open Access
• [Journal Article] Seven-year outcome after 1-year fixed regimen of intravitreal aflibercept injections followed by pro re nata treatment for neovascular age-related macular degeneration (2023)
  • Author(s): Hama Yuki、Miyata Manabu、Ooto Sotaro、Tamura Hiroshi、Ueda-Arakawa Naoko、Muraoka Yuki、Miyake Masahiro、Takahashi Ayako、Wakazono Tomotaka、Uji Akihito、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: Graefe's Archive for Clinical and Experimental Ophthalmology Volume: - Issue: 7 Pages: 1871-1881
  • DOI: 10.1007/s00417-023-05982-w
  • Peer Reviewed
• [Journal Article] Effect of Duration of Macular Detachment on Visual Prognosis after Surgery for Macula-Off Retinal Detachment: Japan-Retinal Detachment Registry (2023)
  • Author(s): Miyake Masahiro、Nakao Shin-ya、Morino Kazuya、Yasukura Shota、Mori Yuki、Ishihara Kenji、Muraoka Yuki、Miyata Manabu、Tamura Hiroshi、Sakamoto Taiji、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Retina Volume: - Issue: 5 Pages: 375-382
  • DOI: 10.1016/j.oret.2023.01.014
  • Peer Reviewed / Open Access
• [Journal Article] Choriocapillaris flow deficit in a pachychoroid spectrum disease using en face optical coherence tomography angiography averaging (2022)
  • Author(s): Tagawa Miho、Ooto Sotaro、Yamashiro Kenji、Tamura Hiroshi、Oishi Akio、Uji Akihito、Miyata Manabu、Miyake Masahiro、Takahashi Ayako、Ichioka Ai、Tsujikawa Akitaka
  • Journal Title: PLOS ONE Volume: 17 Issue: 9 Pages: e0271747-e0271747
  • DOI: 10.1371/journal.pone.0271747
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Natural Course of Pachychoroid Pigment Epitheliopathy (2022)
  • Author(s): Yagi Mariko、Miyake Masahiro、Mori Yuki、Hosoda Yoshikatsu、Takahashi Ayako、Muraoka Yuki、Ueda-Arakawa Naoko、Miyata Manabu、Yamashiro Kenji、Tamura Hiroshi、Ooto Sotaro、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Science Volume: 2 Issue: 4 Pages: 100201-100201
  • DOI: 10.1016/j.xops.2022.100201
  • Peer Reviewed / Open Access
• [Journal Article] Incidence and Clinical Practice of Exudative Age-related Macular Degeneration (2022)
  • Author(s): Kido Ai、Miyake Masahiro、Tamura Hiroshi、Hiragi Shusuke、Kimura Takeshi、Yoshida Satomi、Takeuchi Masato、Ohtera Shosuke、Takahashi Ayako、Ooto Sotaro、Kawakami Koji、Kuroda Tomohiro、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Science Volume: 2 Issue: 2 Pages: 100125-100125
  • DOI: 10.1016/j.xops.2022.100125
  • Peer Reviewed / Open Access
• [Journal Article] Effectiveness of Reduced-fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy (2022)
  • Author(s): Aisu Nao、Miyake Masahiro、Hosoda Yoshikatsu、Mori Yuki、Takahashi Ayako、Muraoka Yuki、Ueda-Arakawa Naoko、Miyata Manabu、Oishi Akio、Tamura Hiroshi、Ooto Sotaro、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Science Volume: 2 Issue: 2 Pages: 100152-100152
  • DOI: 10.1016/j.xops.2022.100152
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide Survival Analysis for Macular Neovascularization Development in Central Serous Chorioretinopathy Revealed Shared Genetic Susceptibility with Polypoidal Choroidal Vasculopathy (2022)
  • Author(s): Mori Yuki、Miyake Masahiro、Hosoda Yoshikatsu、Miki Akiko、Takahashi Ayako、Muraoka Yuki、Miyata Manabu、Sato Takehiro、Tamura Hiroshi、Ooto Sotaro、Yamada Ryo、Yamashiro Kenji、Nakamura Makoto、Tajima Atsushi、Nagasaki Masao、Honda Shigeru、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Volume: 129 Issue: 9 Pages: 1034-1042
  • DOI: 10.1016/j.ophtha.2022.04.018
  • Peer Reviewed
• [Journal Article] Combining optical coherence tomography and fundus photography to improve glaucoma screening. (2022)
  • Author(s): Watanabe T, Hiratsuka Y, Kita Y, Tamura H, Kawasaki R, Yokoyama T, Kawashima M, Nakano T, Yamada M
  • Journal Title: Diagnostics(Basel) Volume: 12（5） Issue: 5 Pages: 1100-1100
  • DOI: 10.3390/diagnostics12051100
  • Peer Reviewed / Open Access
• [Journal Article] Macular atrophy at 5 years after photodynamic therapy for polypoidal choroidal vasculopathy (2022)
  • Author(s): Kentaro Kawai, Manabu Miyata, Sotaro Ooto, Hiroshi Tamura, Naoko Ueda-Arakawa, Ayako Takahashi, Akihito Uji, Yuki Muraoka, Masahiro Miyake, Kenji Yamashiro, Akitaka Tsujikawa
  • Journal Title: Eye Volume: - Issue: 6 Pages: 1067-1072
  • DOI: 10.1038/s41433-022-02067-6
  • Peer Reviewed
• [Journal Article] Integrating Preprocessing Operations into Deep Learning Model: Case Study of Posttreatment Visual Acuity Prediction (2022)
  • Author(s): Otsuki Ryo、Sugiyama Osamu、Mori Yuki、Miyake Masahiro、Hiragi Shusuke、Yamamoto Goshiro、Santos Luciano、Nakanishi Yuta、Hosoda Yoshikatsu、Tamura Hiroshi、Matsumoto Shigemi、Tsujikawa Akitaka、Kuroda Tomohiro
  • Journal Title: Advanced Biomedical Engineering Volume: 11 Issue: 0 Pages: 16-24
  • DOI: 10.14326/abe.11.16
  • NAID: 130008150661
  • ISSN: 2187-5219
  • Peer Reviewed
• [Journal Article] Rescue photodynamic therapy for age-related macular degeneration refractory to anti-vascular endothelial growth factor monotherapy (2022)
  • Author(s): Yoshida Miyo、Oishi Akio、Miyake Masahiro、Ooto Sotaro、Tamura Hiroshi、Miyata Manabu、Takahashi Ayako、Hata Masayuki、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: Photodiagnosis and Photodynamic Therapy Volume: 38 Pages: 102745-102745
  • DOI: 10.1016/j.pdpdt.2022.102745
  • Peer Reviewed
• [Journal Article] PREDICTORS OF RETINAL PIGMENT EPITHELIUM TEAR DEVELOPMENT AFTER TREATMENT FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION USING SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY (2022)
  • Author(s): Yasuhara Satoshi、Miyata Manabu、Ooto Sotaro、Tamura Hiroshi、Ueda-Arakawa Naoko、Uji Akihito、Muraoka Yuki、Miyake Masahiro、Takahashi Ayako、Wakazono Tomotaka、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: Retina Volume: Publish Ahead of Print Issue: 6 Pages: 1020-1027
  • DOI: 10.1097/iae.0000000000003426
  • Peer Reviewed
• [Journal Article] Clinical practice guidelines for pseudoxanthoma elasticum (2017) (2022)
  • Author(s): Iwanaga Akira、Utani Atsushi、Koike Yuta、Okubo Yumi、Kuwatsuka Yutaka、Endo Yuichiro、Tanizaki Hideaki、Wataya‐Kaneda Mari、Hatamochi Atsushi、Minaga Kosuke、Ogi Tomoo、Yamamoto Yosuke、Ikeda Satoshi、Tsuiki Eiko、Tamura Hiroshi、Maemura Koji、Kitaoka Takashi、Murota Hiroyuki
  • Journal Title: The Journal of Dermatology Volume: 49 Issue: 3 Pages: 91-98
  • DOI: 10.1111/1346-8138.16301
  • Peer Reviewed / Open Access
• [Journal Article] Real-world effectiveness of screening programs for age-related macular degeneration: amended Japanese specific health checkups and augmented screening programs with OCT or AI (2022)
  • Author(s): Tamura Hiroshi、Akune Yoko、Hiratsuka Yoshimune、Kawasaki Ryo、Kido Ai、Miyake Masahiro、Goto Rei、Yamada Masakazu
  • Journal Title: Japanese Journal of Ophthalmology Volume: 66 Issue: 1 Pages: 19-32
  • DOI: 10.1007/s10384-021-00890-0
  • NAID: 40022803281
  • Peer Reviewed / Open Access
• [Journal Article] Promotion of Diversity in the Academic Field of Urology : Analysis of 10, 000 Articles Published in Acta Urologica Japonica during a 65-Year Period (2021)
  • Author(s): 小林 恭、田村 寛、平木 秀輔、西田 幸代、宮川 美栄子、黒田 知宏、小川 修
  • Journal Title: 泌尿器科紀要 Volume: 67 Issue: 4 Pages: 125-132
  • DOI: 10.14989/ActaUrolJap_67_4_125
  • NAID: 120007043371
  • ISSN: 0018-1994
  • Year and Date: 2021-04-30
  • Peer Reviewed
• [Journal Article] Contrast-to-noise ratio is a useful predictor of early displacement of large submacular hemorrhage by intravitreal SF6 gas injection (2021)
  • Author(s): Ura Sawako、Miyata Manabu、Ooto Sotaro、Yasuhara Satoshi、Tamura Hiroshi、Ueda-Arakawa Naoko、Muraoka Yuki、Miyake Masahiro、Takahashi Ayako、Wakazono Tomotaka、Uji Akihito、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: Retina Volume: Publish Ahead of Print Issue: 4 Pages: 661-668
  • DOI: 10.1097/iae.0000000000003360
  • Peer Reviewed
• [Journal Article] 眼内レンズ縫着術実施症例の増加：レセプト情報・特定健診等情報（NDB）オープンデータを用いた全数調査 (2021)
  • Author(s): 田村寛、三宅正裕、木戸愛、平木秀輔 、加藤源太 、辻川明孝
  • Journal Title: 日眼会誌 Volume: 125 Pages: 738-740
  • NAID: 40022673494
  • Peer Reviewed
• [Journal Article] Association between topical β-blocker use and asthma attacks in glaucoma patients with asthma: a cohort study using a claims database (2021)
  • Author(s): Kido A, Miyake M, Akagi T, Ikeda HO, Kameda T, Suda K, Hasegawa T, Hiragi S, Yoshida S, Tsujikawa A, Tamura H, Kawakami K
  • Journal Title: Graefes Arch Clin Exp Ophthalmol Volume: 260 Issue: 1 Pages: 271-280
  • DOI: 10.1007/s00417-021-05357-z
  • Peer Reviewed / Open Access
• [Journal Article] Incidence of central serous chorioretinopathy (2011?2018): a nationwide population-based cohort study of Japan (2021)
  • Author(s): Kido Ai、Miyake Masahiro、Tamura Hiroshi、Hiragi Shusuke、Kimura Takeshi、Ohtera Shosuke、Takahashi Ayako、Ooto Sotaro、Kawakami Koji、Kuroda Tomohiro、Tsujikawa Akitaka
  • Journal Title: British Journal of Ophthalmology Volume: NA Issue: 12 Pages: 2021-319403
  • DOI: 10.1136/bjophthalmol-2021-319403
  • Peer Reviewed / Open Access
• [Journal Article] Validation study of the claims-based definition for age-related macular degeneration at a single university hospital in Japan (2021)
  • Author(s): Tamiya Ryosuke、Miyake Masahiro、Kido Ai、Hiragi Shusuke、Tamura Hiroshi、Kuroda Tomohiro、Tsujikawa Akitaka
  • Journal Title: Japanese Journal of Ophthalmology Volume: 65 Issue: 3 Pages: 388-394
  • DOI: 10.1007/s10384-021-00816-w
  • NAID: 40022562056
  • Peer Reviewed
• [Journal Article] Influence of vitreomacular interface score on treatment outcomes of anti-VEGF therapy for neovascular age-related macular degeneration (2021)
  • Author(s): Miyata Manabu、Ooto Sotaro、Yamashiro Kenji、Tamura Hiroshi、Uji Akihito、Miyake Masahiro、Muraoka Yuki、Takahashi Ayako、Tsujikawa Akitaka
  • Journal Title: International Journal of Retina and Vitreous Volume: 7 Issue: 1
  • DOI: 10.1186/s40942-021-00342-4
  • Peer Reviewed
• [Journal Article] Pachychoroid‐phenotype effects on 5‐year visual outcomes of anti‐VEGF monotherapy in polypoidal choroidal vasculopathy (2021)
  • Author(s): Shimizu Yuichiro、Miyata Manabu、Ooto Sotaro、Miyake Masahiro、Mori Yuki、Tamura Hiroshi、Ueda‐Arakawa Naoko、Uji Akihito、Muraoka Yuki、Takahashi Ayako、Wakazono Tomotaka、Yamashiro Kenji、Hata Masayuki、Tsujikawa Akitaka
  • Journal Title: Acta Ophthalmologica Volume: - Issue: 4
  • DOI: 10.1111/aos.15015
  • Peer Reviewed
• [Journal Article] Long-term visual outcome in inferior posterior staphyloma and efficacy of treatment for complicated choroidal neovascularization (2021)
  • Author(s): Doi Ayaka、Miyata Manabu、Ooto Sotaro、Tamura Hiroshi、Ueda-Arakawa Naoko、Uji Akihito、Muraoka Yuki、Miyake Masahiro、Takahashi Ayako、Wakazono Tomotaka、Yamashiro Kenji、Tsujikawa Akitaka
  • Journal Title: American Journal of Ophthalmology Volume: Publish Ahead of Print Pages: 152-159
  • DOI: 10.1016/j.ajo.2021.02.034
  • Peer Reviewed
• [Journal Article] Novel scotoma detection method using time required for fixation to the random targets (2021)
  • Author(s): Takahashi Nobuyuki、Saeki Shozo、Kawahara Minoru、Aman Hirohisa、Nakano Eri、Mori Yuki、Miyake Masahiro、Tamura Hiroshi、Tsujikawa Akitaka
  • Journal Title: Medxrive Volume: -
  • DOI: 10.1101/2021.06.03.21258101
  • Open Access
• [Journal Article] Distribution of Choroidal Thickness and Choroidal Vessel Dilation in Healthy Japanese Individuals (2021)
  • Author(s): Mori Yuki、Miyake Masahiro、Hosoda Yoshikatsu、Uji Akihito、Nakano Eri、Takahashi Ayako、Muraoka Yuki、Miyata Manabu、Tamura Hiroshi、Ooto Sotaro、Tabara Yasuharu、Yamashiro Kenji、Matsuda Fumihiko、Tsujikawa Akitaka、Nakayama Takeo、Sekine Akihiro、Kosugi Shinji、Tabara Yasuharu、Matsuda Fumihiko
  • Journal Title: Ophthalmology Science Volume: 1 Issue: 2 Pages: 100033-100033
  • DOI: 10.1016/j.xops.2021.100033
  • Peer Reviewed / Open Access
• [Journal Article] Clinical and Genetic Characteristics of Pachydrusen in Eyes with Central Serous Chorioretinopathy and General Japanese Individuals (2020)
  • Author(s): Takahashi Ayako、Hosoda Yoshikatsu、Miyake Masahiro、Miyata Manabu、Oishi Akio、Tamura Hitoshi、Ooto Sotaro、Yamashiro Kenji、Tabara Yasuharu、Matsuda Fumihiko、Tsujikawa Akitaka
  • Journal Title: Ophthalmology Retina Volume: in press Issue: 9 Pages: 910-917
  • DOI: 10.1016/j.oret.2020.12.004
  • Peer Reviewed
• [Journal Article] Relationship between Intraocular Pressure and Coffee Consumption in a Japanese Population without Glaucoma: The Nagahama Study (2020)
  • Author(s): Nakano E, Miyake M, Hosoda Y, Mori Y, Suda K, Kameda T, Ikeda-Ohashi H, Tabara Y, Yamashiro K, Tamura H, Akagi T, Matsuda F, Tsujikawa A; Nagahama Study Group
  • Journal Title: Ophthalmol Glaucoma Volume: 4196 Issue: 3 Pages: 30271-30274
  • DOI: 10.1016/j.ogla.2020.09.019
  • Peer Reviewed
• [Presentation] NDBを用いた患者調査各項目の再現の検討 (2023)
  • Author(s): 加藤 源太, 田村 寛, 植嶋 大晃, 森 由希子, 平木 秀輔, 酒井 未知, 大寺 祥佑, 野田 龍也, 児玉 知子, 佐藤 大介, 奥村 泰之
  • Organizer: 医療情報学連合大会
• [Presentation] 加齢黄斑変性治療後の予後を予測するための時系列画像解析 (2023)
  • Author(s): Haruka Nishida; Kazumasa Kishimoto; Osamu Sugiyama; Hiroaki Ueshima; Takuro Kamei; Goshiro Yamamoto; Tomohiro Kuroda; Masahiro Miyake; Hiroshi Tamura
  • Organizer: 生体医工学シンポジウム 2023
• [Presentation] ナショナルデータベースを用いた網膜色素線条症と弾性繊維性仮性黄色腫の疫学調査 (2023)
  • Author(s): 和田沙織; 田村 寛; 三宅正裕; 木戸 愛; 亀井拓郎; 平木秀輔; 植嶋大晃; 辻川明孝
  • Organizer: 第127回日本眼科学会総会
• [Presentation] 中心性漿液性脈絡網膜症における網膜下液の自然吸収と後極の脈絡膜血管径との関連 (2023)
  • Author(s): 古郷貴裕; 村岡勇貴; 石倉雅治; 錦織奈緒美; 高橋綾子; 三宅正裕; 上田奈央子; 宮田 学; 田村 寛; 畑 匡侑; 辻川明孝
  • Organizer: 第127回日本眼科学会総会
• [Presentation] 滲出型加齢黄斑変性におけるFaricimab硝子体内投与の短期治療効果と安全性 (2023)
  • Author(s): 土川愛美利; 上田奈央子; 田村 寛; 宮田 学; 三宅正裕; 高橋綾子; 畑 匡侑; 木戸 愛; 田川美穂; 辻川明孝
  • Organizer: 第127回日本眼科学会総会
• [Presentation] フォン・ヒッペル・リンドウ病、日本における疫学調査とその展望 (2022)
  • Author(s): 高橋綾子, 木戸 愛, 三宅正裕, 田村 寛, 辻川明孝
  • Organizer: 第128回京都眼科学会
• [Presentation] APMPPE症例のmultimodal imaging (2022)
  • Author(s): 上田奈央子, 田村 寛, 宮田 学, 三宅正裕, 高橋綾子, 木戸 愛, 辻川明孝
  • Organizer: 第128回京都眼科学会
• [Presentation] レセプト情報・特定健診等情報データベースを利用した日本人における斜視の病型調査 (2022)
  • Author(s): 宮田 学, 木戸 愛, 田村 寛, 三宅正裕, 亀井拓郎, 和田沙織, 河合健太郎, 中尾真也, 山本昭成, 須田謙史, 中野絵梨, 田川美穂, 辻川明孝
  • Organizer: 第128回京都眼科学会
• [Presentation] 視線分析型自動視野計による眼球サッケード運動解析と認知機能検査結果との関連 (2022)
  • Author(s): 中野 絵梨, 三宅 正裕, 森 雄貴, 田村 寛, 辻川 明孝
  • Organizer: 日本サルコペニア・フレイル学会
• [Presentation] Incidence of Central Serous Chorioretinopathy in Japan: A Nationwide Population-Based Cohort Study. (2021)
  • Author(s): Ai Kido, Masahiro Miyake, Hiroshi Tamura, Ayako Takahashi, Sotaro Ooto, Akitaka Tsujikawa
  • Organizer: Association for Research in Vision and Ophthalmology 2021
  • Int'l Joint Research
• [Presentation] ナショナルデータベースを用いた本邦における中心性漿液性脈絡網膜症の疫学研究 (2021)
  • Author(s): 木戸 愛, 三宅正裕, 田村 寛, 平木秀輔, 田宮良輔, 高橋綾子, 大音壮太郎, 辻川明孝
  • Organizer: 網膜硝子体学会
• [Presentation] ナショナルデータベースを用いた本邦における加齢黄斑変性の疫学と診療実態調査 (2021)
  • Author(s): 木戸愛、三宅正裕、田村寛、平木秀輔、田宮良輔、高橋綾子、大音壮太郎、辻川明孝
  • Organizer: 日本眼科学会総会
• [Presentation] Incidence of Central Serous Chorioretinopathy in Japan: A Nationwide Population-Based Cohort Study (2021)
  • Author(s): Ai Kido, Masahiro Miyake, Ayako Takahashi, Sotaro Ooto, Hiroshi Tamura, Akitaka Tsujikawa
  • Organizer: The 14th Joint Meeting of Japan-China-Korea Ophthalmologists
  • Int'l Joint Research
• [Book] 最新 眼科画像診断パワーアップ－検査の基本から最新機器の撮影法まで眼科診療エクレール (2023)
  • Author(s): 辻川明孝
  • Total Pages: 400
  • Publisher: 中山書店
  • ISBN: 9784521750521
• [Book] 講義実録 統計入門 (2023)
  • Author(s): データ科学イノベーション教育研究センター
  • Total Pages: 420
  • Publisher: 現代図書
  • ISBN: 9784434318573
• [Book] 専門医必携 眼科鑑別診断実力アップQ&A 179-181ページ (2021)
  • Author(s): 山田 昌和、平塚 義宗
  • Total Pages: 288
  • Publisher: 南江堂
  • ISBN: 9784524249619
• [Remarks] 日本人の50人に1人が斜視 匿名医療保険等関連データベースを用いた解析
  • URL: https://medical-tribune.co.jp/news/2023/1226560522/?utm_source=Pickup&utm_medium=email&utm_campaign=mailmag231223
• [Remarks] 日本人の50人に1人が斜視
  • URL: https://medical.jiji.com/news/58198
• [Remarks] 「日本人の50人に1人が斜視」若年層・高齢層に顕著 京都大学ら研究グループ発表
  • URL: https://news.yahoo.co.jp/articles/90a657918ec7f3fc35e2e2605c3c101c6121048d,
• [Remarks] 日本人の50人に1人が「斜視」 京都大学の分析で判明、世界初の全国民調査
  • URL: https://www.kyoto-np.co.jp/articles/-/1203119
• [Remarks] 両目で視線がずれる「斜視」、全国民の50人に1人 京大が分析
  • URL: https://www.asahi.com/articles/ASS3M5KBTS3LPLBJ002.html?fbclid=IwAR2kDcIPIGalzv3MO6c-TQ1xwhHmcAlZ2jIw0YcQJ2EIf3pg5AYsQKajQiI
• [Remarks] 失明原因となる加齢黄斑変性の日本人の疫学と治療実態を明らかに
  • URL: https://www.kyoto-u.ac.jp/ja/research-news/2022-03-04-0?fbclid=IwAR26xDsVM_3pGGjGZGQRdTdRl0PclVnCSeRRcV9NhHsKkFMVQxAWJdKcm9M
• [Remarks] 国の診療報酬請求データベースを用いて特殊な網膜剥離の発症率を明らかに
  • URL: https://www.kyoto-u.ac.jp/ja/research-news/2021-07-19