• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Cohort study of a population with specific health examination data, dental health examination data, medical cost data, and saliva samples

Research Project

Project/Area Number 21K10205
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 57080:Social dentistry-related
Research InstitutionShinshu University

Principal Investigator

Kurita Hiroshi  信州大学, 学術研究院医学系, 教授 (10273103)

Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2023: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2022: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2021: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords歯科保健 / 歯科口腔保健 / インフルエンザ / 口腔乾燥 / 高血圧症 / 特定健診 / 歯科健診 / 唾液検査 / 咀嚼 / 特定問診 / 口腔衛生状態 / 唾液腺 / 唾液
Outline of Research at the Start

目的:口腔と全身との関連に関する質の高いエビデンス、および、新たなエビデンスをみいだす。また、今後の研究に備えたデータベースを構築する。対象および方法: 2014年から長野県塩尻市および安曇野に整備しているコホート(国保特定健診・問診、歯科健診・歯科問診、国民保険データベース(KDB)データ、唾液サンプルが紐付けされたデータベース)を使用し、歯科受診によりMETSは改善するか?インフルエンザ、腎機能障害と歯科疾患・口腔機能との関連を明らかにする。また、国保特定健診、歯科健診、レセプトデータと紐付けされた唾液サンプルのデータベースを整備し、新たな研究へと続けていく。

Outline of Final Research Achievements

By analyzing cohort data (specific health examinations/questionnaires, dental health examinations/ questionnaires, saliva samples, and medical cost data), we generated high-quality evidence on the relationship between oral and general health, and explored new associations between them. As a result, the following results were obtained. (1) Association between oral hygiene and influenza: Those with poor oral hygiene were 1.63 times more likely to develop influenza than those with good oral hygiene. (2) Association between xerostomia and hypertension: Hypertension is one of the causes of xerostomia. (iii) Questionnaire on masticatory function incorporated into specific health checkups was effective in reflecting oral conditions and in improving oral and metabolic syndrome.

Academic Significance and Societal Importance of the Research Achievements

本研究により、口腔と全身の健康との関連に関する、エビデンスに基づいた新たな知見が得られた。これらの知見により歯および口腔の健康に関する関心が高まり、歯科・口腔疾患を予防し、口腔機能を維持・向上させることは、健康余命の増進、医療費の抑制、生活の質の向上をもたらすであろう。また、本研究の継続により、特定健診結果、歯科口腔健診結果、医療費データ、唾液サンプルを紐付けした将来的・継続的なデータベースが構築されている。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (9 results)

All 2024 2022 2021

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] The effectiveness of a self‐reported questionnaire on masticatory function in health examinations2024

    • Author(s)
      Kazunori Anzai, Hironori Sakai, Eiji Kondo, Hirokazu Tanaka, Akinobu Shibata, Masao Hashidume, Hiroshi Kurita
    • Journal Title

      Odontology

      Volume: - Issue: 4 Pages: 1361-1369

    • DOI

      10.1007/s10266-024-00943-z

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Exploration of correlation of oral hygiene and condition with influenza infection2021

    • Author(s)
      Kawamoto M, Tanaka H, Sakurai A, Otagiri H, Karasawa I, Yamada SI, Kurita H
    • Journal Title

      PLoS One

      Volume: 16 Issue: 8 Pages: e0254981-e0254981

    • DOI

      10.1371/journal.pone.0254981

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between dry mouth and hypertension2021

    • Author(s)
      Kawamoto M, Yamada SI, Gibo T, Kajihara R, Nagashio S, Tanaka H, Yajima J, Takizawa A, Kondo E, Sakai H, Kaneko T, Uehara T, Kurita H
    • Journal Title

      Clin Oral Ingvestig

      Volume: 25 Issue: 9 Pages: 5217-5225

    • DOI

      10.1007/s00784-021-03829-4

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Accuracy of a salivary examination kit for the screening of periodontal disease in a group medical check-up (Japanese-specific health check-up)2021

    • Author(s)
      Sakurai A, Yamada SI, Karasawa I, Kondo E, Kurita H
    • Journal Title

      Medicine (Baltimore)

      Volume: 100 Issue: 6 Pages: e24539-e24539

    • DOI

      10.1097/md.0000000000024539

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Presentation] 特定健診への歯科健診導入による効果の検討:歯科受診行動の変化2022

    • Author(s)
      神戸宏仁、栗田 浩、ほか
    • Organizer
      日本口腔科学会総会学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 口腔衛生状態とインフルエンザ感染の関連性の検討2021

    • Author(s)
      田中宏和、山田慎一、川本真貴子、小田切宏樹、櫻井精斉、栗田 浩
    • Organizer
      日本口腔科学会総会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 唾液性状とメタボリックシンドロームの関係2021

    • Author(s)
      鈴木大介、山田慎一、櫻井精斉、唐澤今人、近藤英司、酒井洋徳、栗田 浩
    • Organizer
      日本口腔科学会総会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] Exploration of correlation of oral hygiene and condition with influenza infection2021

    • Author(s)
      Tanaka H, Yamada S, Kawamoto M, Sakurai A, Otagiri H, Karasawa I, Kurita H
    • Organizer
      The 1st Annual Meeting of the International Society of Oral Care
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 教育講演:知っている?歯科口腔内環境と生活習慣病の関係2021

    • Author(s)
      栗田 浩
    • Organizer
      第94回日本産業衛生学会
    • Related Report
      2021 Research-status Report
    • Invited

URL: 

Published: 2021-04-28   Modified: 2025-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi