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Elucidate the mechanism of frail development through longitudinal studies and devise an intervention programs.

Research Project

Project/Area Number 21K11007
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58080:Gerontological nursing and community health nursing-related
Research InstitutionPrefectural University of Hiroshima

Principal Investigator

IIDA Tadayuki  県立広島大学, 保健福祉学部(三原キャンパス), 教授 (50290549)

Co-Investigator(Kenkyū-buntansha) 伊藤 康宏  四日市看護医療大学, 看護医療学部, 教授 (40176368)
原田 俊英  県立広島大学, 保健福祉学部(三原キャンパス), 名誉教授 (60181020)
青井 聡美  県立広島大学, 保健福祉学部(三原キャンパス), 教授 (10321217)
池田 ひろみ  県立広島大学, 保健福祉学部(三原キャンパス), 准教授 (60448800)
巽 あさみ  人間環境大学, 看護学部, 教授 (90298513)
Project Period (FY) 2021-04-01 – 2025-03-31
Project Status Completed (Fiscal Year 2024)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2022: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsサルコペニア / フレイル / メタボリックシンドローム指標 / 後期高齢者基本健診 / 傾向スコアマッチング / 骨密度 / 筋量 / 高齢者 / 生活習慣 / 女性 / 高齢期 / 生活習慣病 / 体組成
Outline of Research at the Start

本研究では,中年期の生活習慣や健康状態,あるいはこれらの変化が,骨密度を含めた高齢期のフレイル発現リスクといかなる関連性を有するかを明らかにし(症例対照研究),フレイルへの移行要因に応じた介入プログラムの効果検証を生活習慣,心理(含,認知機能),骨密度・筋肉量といった主観的および客観的評価を用いて経時的に実施する(介入研究)。介入は,アプリで栄養や運動状況,気分などの心理的な状況を個々でモニタリングしつつ,アミューズメントを用いた社会的交流の場を設け,問題が生じた際に,的確に対応できるシステムを構築する。地方自治体と協働で取り組み健康寿命延伸を目指した先制的な健康に役立てる。

Outline of Final Research Achievements

To develop strategies against sarcopenia, physiological and biochemical data in older women were analyzed using propensity score matching. The elderly woman aged > 65 years with the AWGS calf circumference < 33 cm were included in the sarcopenia risk group. Propensity score matching adjusted for age and BMI was performed between the possible-sarcopenia group and the sarcopenia risk group. The comparison included nutritional index, metabolic syndrome parameters, BMD, and skeletal muscle mass index score between both groups. Study results suggest that exercise increases muscle strength and muscular endurance to improve HDL-cho may be effective.

Academic Significance and Societal Importance of the Research Achievements

フレイルは,加齢に伴い,生理的予備能が低下した状態であり,健康な状態と要介護の中間の状態と定義されている。フレイルには,身体的,精神・心理的,社会的があり,健常な状態に復帰できる可逆性を有している。本研究では,中年期の生活習慣や健康状態,あるいはこれらの変化が,骨密度を含めた高齢期のフレイル発現リスクといかなる関連性を有するかを明らかにし(症例対照研究),骨密度・筋肉量といった主観的および客観的評価を用いて経時的に実施した。

Report

(5 results)
  • 2024 Annual Research Report   Final Research Report ( PDF )
  • 2023 Research-status Report
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (9 results)

All 2024 2023 2022 2021

All Journal Article (9 results) (of which Peer Reviewed: 8 results,  Open Access: 8 results)

  • [Journal Article] Relationship Between Psychological Stress Scores and Urinary 5-HT Levels Over Time Under Psychological Stress2024

    • Author(s)
      Iida Tadayuki、Ito Yasuhiro、Murayama Susumu、Yoshimaru Yuki、Tatsumi Asami
    • Journal Title

      International Journal of Tryptophan Research

      Volume: 17 Pages: 1-10

    • DOI

      10.1177/11786469241297911

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Cross-Sectional Study on Metabolic Syndrome Parameters, the Nutritional Index, and Physical Status Associated with or Without the Possible Diagnosed Sarcopenia in Older Women Using A Propensity Score Matching Method2024

    • Author(s)
      Iida Tadayuki、Aoi Satomi、Kunishige Masafumi、Kawane Yuka、Obata Yuto、Nishigaki Masaya、Kodama Miwako
    • Journal Title

      Journal of Frailty, Sarcopenia and Falls

      Volume: 09 Issue: 02 Pages: 142-150

    • DOI

      10.22540/jfsf-09-142

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluating the impact of a darts game intervention on cognitive function in older adults with and without mild cognitive impairment: a pilot study2024

    • Author(s)
      Kawabata Nami、Iida Tadayuki、Kunishige Masafumi、Fukuda Hiroshi、Miyaguchi Hideki、Harada Toshihide
    • Journal Title

      Frontiers in Rehabilitation Sciences

      Volume: 5 Pages: 1327494-1327494

    • DOI

      10.3389/fresc.2024.1327494

    • Related Report
      2023 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of Continuous Intake of Lemon Drink with Added Calcium during Growth Period on Bone Density.2023

    • Author(s)
      Hiromi Ikeda; Tadayuki Iida; Masanori Hiramitsu; Takashi Inoue; Toshihide Harada
    • Journal Title

      International Medical Journal

      Volume: 30 Pages: 79-79

    • Related Report
      2023 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psychosocial work characteristics and low back pain in daycare (nursery) workers in Japan: a prospective cohort study2022

    • Author(s)
      Shi Xuliang、Aoshima Megumi、Iida Tadayuki、Hiruta Shuichi、Ono Yuichiro、Ota Atsuhiko
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: 23 Issue: 1 Pages: 1055-1055

    • DOI

      10.1186/s12891-022-06009-x

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Mammary Gland Disease With Metabolic Syndrome Factors in Japanese Women?Case-Control Study Based on Health Screening Results2022

    • Author(s)
      Sumida Sakika、Iida Tadayuki、Yoshikawa Masao、Nagaoka Kaoru
    • Journal Title

      Breast Cancer: Basic and Clinical Research

      Volume: 16

    • DOI

      10.1177/11782234221127652

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Citric Acid in Lemon Water on the Human Intestinal Microbiota: A Comparison between Pre-Meal Intake of Water and Lemon Water.2021

    • Author(s)
      Iida T, Ishigami S, Kunishige M, Sasagawa S, Ikeda H, Aoi S, Harada T.
    • Journal Title

      International Medical Journal

      Volume: 28 Pages: 625-628

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Changes in Physiological Indicators due to Perilla Oil Intake in Japanese People.2021

    • Author(s)
      Kato Y, Umei N, Harada T, Iida T, Aoi S, Miyake Y, Sato Y.
    • Journal Title

      International Medical Journal

      Volume: 28 Pages: 331-334

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 軽度要介護認定率と地域での介護予防ボランティア活動状況の関連.2021

    • Author(s)
      田中 聡, 積山 和加子, 佐藤 勇太, 飯田 忠行, 香川 広美, 古西 恭子, 高橋 彰, 久留飛 高成.
    • Journal Title

      総合リハビリテーション

      Volume: 49 Pages: 583-588

    • NAID

      40022581523

    • Related Report
      2021 Research-status Report

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Published: 2021-04-28   Modified: 2026-01-16  

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