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Mechanism of Sleep Induction and Facilitation by Galvanic Vestibular Stimulation

Research Project

Project/Area Number 21K11545
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59030:Physical education, and physical and health education-related
Research InstitutionThe University of Tokyo

Principal Investigator

Kishi Akifumi  東京大学, 大学院医学系研究科(医学部), 特任講師 (70748946)

Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2023: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2022: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2021: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords睡眠 / 非侵襲的脳刺激
Outline of Research at the Start

本研究では、身体の揺動感覚を惹起する低周波前庭電流刺激が、睡眠の導入・促進効果を有するかを明らかにすることを目的とする。特に、睡眠中および睡眠前30分間の持続的前庭電流刺激が、それぞれ入眠過程の脳状態及び自律神経活動のダイナミクスに及ぼす影響を明らかにし、睡眠の質を改善し得るかを明らかにする。

Outline of Final Research Achievements

The purpose of this study was to determine whether galvanic vestibular stimulation has an effect on sleep onset and facilitation. Sleep was evaluated by polysomnographic recordings consisting of electroencephalography, electrooculography, and electromyography. The experiment was designed so that after the acclimation condition, the Stimulation and Sham conditions were performed in random order. Data analysis suggested that current stimulation of appropriate intensity to the vestibular systems had a sleep induction and facilitation effect in healthy young adults. In addition to these studies, we proposed a conceptual model of sleep dynamics in humans as a basis for sleep manipulation research using noninvasive brain stimulation and quantification of individual differences in sleep dynamics.

Translated with DeepL.com (free version)

Academic Significance and Societal Importance of the Research Achievements

本研究で得られた成果は、睡眠覚醒に関わる脳ダイナミクスの制御が可能であることを示唆するとともに、良質な睡眠の獲得に資する新たな技術開発につながる点で学術的・社会的意義を有するものと考えられる。

Report

(3 results)
  • 2023 Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (9 results)

All 2023 2022 2021

All Journal Article (3 results) Presentation (6 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results)

  • [Journal Article] 運動・睡眠と記憶の関わり(1)2022

    • Author(s)
      岸 哲史
    • Journal Title

      月刊スポーツメディスン

      Volume: 34 Pages: 39-41

    • Related Report
      2022 Research-status Report
  • [Journal Article] 運動・睡眠と記憶の関わり(2)2022

    • Author(s)
      岸 哲史
    • Journal Title

      月刊スポーツメディスン

      Volume: 34 Pages: 39-41

    • Related Report
      2022 Research-status Report
  • [Journal Article] ICT/IoT技術を用いた睡眠改善法の展望:精神疾患の予防に向けて2021

    • Author(s)
      岸 哲史,竹内皓紀,中村亨,吉内一浩,山本義春
    • Journal Title

      精神科

      Volume: 39 Pages: 623-629

    • Related Report
      2021 Research-status Report
  • [Presentation] Slow-oscillatory galvanic vestibular stimulation promotes sleep physiology in healthy young adults.2023

    • Author(s)
      Kishi, A., F. Togo, Y. Yamamoto
    • Organizer
      5th International Brain Stimulation Conference
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] The effects of slow-oscillatory galvanic vestibular stimulation on sleep physiology in healthy humans.2022

    • Author(s)
      Kishi, A., F. Togo, Y. Yamamoto.
    • Organizer
      The SLEEP 2022 36th Annual Meeting of the Associated Professional Sleep Societies, LLC.
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Towards understanding and controlling human sleep dynamics.2022

    • Author(s)
      Kishi, A.
    • Organizer
      4th International 33rd National Biophysics Congress
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] ヒト睡眠ダイナミクスの解析・評価・制御.2022

    • Author(s)
      岸 哲史
    • Organizer
      計測自動制御学会ライフエンジニアリング部門シンポジウム2022
    • Related Report
      2022 Research-status Report
  • [Presentation] Sleep stage dynamics in patients with narcolepsy and other hypersomnias2021

    • Author(s)
      岸哲史,北島剛司,河合諒子,廣瀬真里奈,岩田仲生,山本義春
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] ヒト睡眠ダイナミクスの機序解明と操作への展望2021

    • Author(s)
      岸哲史
    • Organizer
      第29回身体運動科学公開シンポジウム
    • Related Report
      2021 Research-status Report
    • Invited

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Published: 2021-04-28   Modified: 2025-01-30  

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