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The use of real-world data for non-communicable diseases, atherosclerosis and disability

Research Project

Project/Area Number 21K11569
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionNiigata University

Principal Investigator

Fujihara Kazuya  新潟大学, 医歯学総合研究科, 特任准教授 (10779341)

Co-Investigator(Kenkyū-buntansha) 曽根 博仁  新潟大学, 医歯学系, 教授 (30312846)
児玉 暁  新潟大学, 医歯学総合研究科, 特任准教授 (50638781)
Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2022: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords生活習慣病 / 臨床疫学 / データサイエンス / 医療ビッグデータ / リアルワールドデータ / 健康寿命延伸 / 寛解 / 介護
Outline of Research at the Start

本研究は、以下に示す研究計画の通り、以下の1で構築したデータベースを基に2のプロジェクトを実施する。
1. 健診・健康保険レセプト・介護発生/重症化を一体化したデータベースの構築
匿名化した上で収集された薬剤/歯科情報を含む膨大なレセプト情報、臨床指標(血液検査/生活習慣調査)、介護要因並びに増悪の情報を含む介護保険情報を連結可能匿名化し、約1万人を個人突合する
2. 介護発生の誘因となるアウトカムの発生及び介護発生/重症化リスクの解析
95%以上の正確性をもつ独自システムを用いた診療内容の医学的評価を基盤とした手法から、イベントと介護保険情報と照らし合わせ、介護発生/増悪のリスク因子を分析する。

Outline of Final Research Achievements

Shorter healthy life expectancy is a serious problem not only in terms of reduced quality of life but also in terms of socioeconomic impact. While progress is being made in generating scientific evidence using real-world data in adults, there are many obstacles to conducting research in the area of the elderly, and data construction/analysis has lagged far behind. We will build a real-world database specialized for nursing care analysis by combining it with accurate outcome determinations based on medical evaluations by actual practitioners in the field. Longitudinal analysis of the data will generate scientific evidence to facilitate on-site practice of “individualized prevention and guidance,” which cannot be obtained from conventional cross-sectional data or individual cohort studies.

Translated with DeepL.com (free version)

Academic Significance and Societal Importance of the Research Achievements

今回、95%以上の正確性をもつ独自システムを用いた診療内容の医学的評価を基盤とした手法から、心筋梗塞、心不全、脳卒中、腎透析、下肢切断、失明、骨折、認知症の発生状況を判定する100万人を超えるデータベースの構築に取り組み、一部に関してはデータベース基盤を確立した。そのデータを用い、動脈硬化性疾患のリスク因子の解明を含め、多くの成果を報告した。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (71 results)

All 2024 2023 2022 2021

All Journal Article (19 results) (of which Peer Reviewed: 19 results,  Open Access: 17 results) Presentation (52 results) (of which Int'l Joint Research: 24 results,  Invited: 5 results)

  • [Journal Article] Cross-Sectional and Longitudinal Associations between Forearm Bone Mineral Density and Anthropometry in Adult Japanese Men and Women2024

    • Author(s)
      Ishizawa Masahiro、Fujihara Kazuya、Yachida Junko、Ikeda Izumi、Sato Takaaki、Yamada Takaho、Kobayashi Ayako、Tanaka Shiro、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi、Tashiro Minoru、Kodama Satoru、Kato Kiminori、Sone Hirohito
    • Journal Title

      Journal of Bone Metabolism

      Volume: 31 Issue: 1 Pages: 21-30

    • DOI

      10.11005/jbm.2024.31.1.21

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between screen time, including that for smartphones, and overweight/obesity among children in Japan: NICE EVIDENCE Study 42024

    • Author(s)
      Ikeda Izumi、Fujihara Kazuya、Morikawa Yoshizawa Sakiko、Takeda Yasunaga、Ishiguro Hajime、Yamada Harada Mayuko、Horikawa Chika、Matsubayashi Yasuhiro、Yamada Takaho、Ogawa Yohei、Sone Hirohito
    • Journal Title

      Endocrine Journal

      Volume: 71 Issue: 2 Pages: 171-179

    • DOI

      10.1507/endocrj.EJ23-0343

    • ISSN
      0918-8959, 1348-4540
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Incidence and predictors of remission and relapse of type 2 diabetes mellitus in Japan: Analysis of a nationwide patient registry (JDDM73)2023

    • Author(s)
      Fujihara Kazuya、Khin Laymon、Murai Koshiro、Yamazaki Yurie、Tsuruoka Kahori、Yagyuda Noriko、Yamazaki Katsuya、Maegawa Hiroshi、Tanaka Shiro、Kodama Satoru、Sone Hirohito、JDDM Study Group
    • Journal Title

      Diabetes, Obesity and Metabolism

      Volume: 25 Issue: 8 Pages: 2227-2235

    • DOI

      10.1111/dom.15100

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between the magnitude of body mass index reductions and remission in patients with type 2 diabetes in real world settings: Analysis of nationwide patient registry in Japan (<scp>JDDM</scp>74)2023

    • Author(s)
      Fujihara Kazuya、Khin Laymon、Murai Koshiro、Yamazaki Yurie、Tsuruoka Kahori、Yagyuda Noriko、Yamazaki Katsuya、Maegawa Hiroshi、Tanaka Shiro、Kodama Satoru、Sone Hirohito、JDDM Study Group
    • Journal Title

      Diabetes, Obesity and Metabolism

      Volume: 25 Issue: 11 Pages: 3125-3135

    • DOI

      10.1111/dom.15206

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Network meta-analysis of glucose-lowering drug treatment regimens with the potential risk of hypoglycemia in patients with type 2 diabetes mellitus in terms of glycemic control and severe hypoglycemia2023

    • Author(s)
      Kodama Satoru、Fujihara Kazuya、Ishiguro Hajime、Matsubayashi Yasuhiro、Kitazawa Masaru、Iwanaga Midori、Yamada Takaho、Kato Kiminori、Nakagawa Yoshimi、Tanaka Shiro、Shimano Hitoshi、Sone Hirohito
    • Journal Title

      Journal of Investigative Medicine

      Volume: 71 Issue: 4 Pages: 400-410

    • DOI

      10.1177/10815589221149188

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Machine Learning Approach to Drug Treatment Strategy for Diabetes Care.2023

    • Author(s)
      Fujihara K, Sone H.
    • Journal Title

      Diabetes Metab J.

      Volume: Online ahead of print. Issue: 3 Pages: 325-332

    • DOI

      10.4093/dmj.2022.0349

    • Related Report
      2023 Annual Research Report 2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Utility of a Physical Fitness Score in Screening for Chronic Diseases.2023

    • Author(s)
      Sato T, Fujihara K, Yamada H.M, Chou K, Yaguchi Y, Kitazawa M, Ishiguro H, Osawa T, Yamada T, Kodama S, Kato K, Sone H.
    • Journal Title

      J Sports Sci Med

      Volume: 22 Pages: 98-110

    • DOI

      10.52082/jssm.2023.98

    • Related Report
      2023 Annual Research Report 2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Combined effects of blood pressure and glycemic status on risk of heart failure: a population-based study2023

    • Author(s)
      Kobayashi Ayako、Fujihara Kazuya、Yamada Mayuko Harada、Sato Takaaki、Yaguchi Yuta、Kitazawa Masaru、Matsubayashi Yasuhiro、Iwanaga Midori、Yamada Takaho、Kodama Satoru、Sone Hirohito
    • Journal Title

      Journal of Hypertension

      Volume: 41 Pages: 470-475

    • DOI

      10.1097/hjh.0000000000003362

    • Related Report
      2023 Annual Research Report 2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability2023

    • Author(s)
      Kodera Remi、Fujihara Kazuya、Koyama Tetsuya、Shiozaki Haruka、Mutsuma Yurie、Yagyuda Noriko、Hatta Mariko、Tsuruoka Kahori、Takeda Yasunada、Araki Atsushi、Sone Hirohito
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 20793-20793

    • DOI

      10.1038/s41598-023-47913-z

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Retrospective cohort study to examine the association between serum amylase and the incidence of type 2 diabetes mellitus, Toranomon Hospital Health Management Center Study 23 (TOPICS 23)2023

    • Author(s)
      Ikeda Izumi、Fujihara Kazuya、Osawa Taeko、Takeda Yasunaga、Hatta Mariko、Matsubayashi Yasuhiro、Kodama Satoru、Mori Yasumichi、Kadowaki Takashi、Honda Ritsuko、Arase Yasuji、Sone Hirohito
    • Journal Title

      BMJ Open Diabetes Research &amp; Care

      Volume: 11 Issue: 4 Pages: e003482-e003482

    • DOI

      10.1136/bmjdrc-2023-003482

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations among metabolic health, weight status, and various physical fitness components in Japanese adolescents: a cross-sectional study (NICE EVIDENCE study- Agano 3)2023

    • Author(s)
      Morikawa Sakiko Yoshizawa、Takeda Yasunaga、Fujihara Kazuya、Ikeda Izumi、Kobayashi Ayako、Hatta Mariko、Mitsuma Yurie、Horikawa Chika、Ishiguro Hajime、Yamada Takaho、Ogawa Yohei、Sone Hirohito
    • Journal Title

      Journal of Sports Sciences

      Volume: 41 Issue: 13 Pages: 1279-1289

    • DOI

      10.1080/02640414.2023.2268358

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fast walking and physical activity are independent contributors to improved physical function2023

    • Author(s)
      Shiozaki H, Fujihara K*, Yamada NH, Yamamoto M, Mitsuma Y, Kitazawa M, Yaguchi Y, Matsubayashi Y, Iwanaga M, Yamada T, Kodama S, Sone H
    • Journal Title

      Family Practice

      Volume: 40 Issue: 2 Pages: 398-401

    • DOI

      10.1093/fampra/cmac087

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of the estimated glomerular filtration rate (eGFR) and/or proteinuria to predict the risk of initiation of dialysis in people with and without diabetes2022

    • Author(s)
      Osawa T, Fujihara K*, Yamada MH, Yaguchi Y, Sato T, Kitazawa M, Matsubayashi Y, Yamada T, Kodama S, Sone H
    • Journal Title

      Diabetology Intern

      Volume: 14 Issue: 1 Pages: 86-63

    • DOI

      10.1007/s13340-022-00603-z

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Accuracy of Japanese Claims Data in Identifying Diabetes-Related Complications2021

    • Author(s)
      Fujihara K, Yamada-Harada M, Matsubayashi Y, Kitazawa M, Yamamoto M, Yaguchi Y, Seida H, Kodama S, Akazawa K, Sone H
    • Journal Title

      Pharmacoepidemiol Drug Saf.

      Volume: 30(5) Issue: 5 Pages: 594-601

    • DOI

      10.1002/pds.5213

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Carrot Consumption Frequency Associated with Reduced BMI and Obesity through the SNP Intermediary rs44457112021

    • Author(s)
      Fujihara K, Nogawa S, Saito K, Horikawa C, Takeda Y, Cho K, Ishiguro H, Kodama S, Nakagawa Y, Matsuzaka T, Shimano H, Sone H
    • Journal Title

      Nutrients

      Volume: 13 Issue: 10 Pages: 3478-3478

    • DOI

      10.3390/nu13103478

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of prior cerebrovascular disease and glucose status on incident cerebrovascular disease in Japanese2021

    • Author(s)
      Oe M, Fujihara K, Harada-Yamada M, Osawa T, Kitazawa M, Matsubayashi Y, Sato T, Yaguchi Y, Iwanaga M, Seida H, Yamada T, Sone H
    • Journal Title

      Cardiovascular Diabetology

      Volume: 20 Issue: 1 Pages: 174-174

    • DOI

      10.1186/s12933-021-01367-7

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations of Systolic Blood Pressure and Diastolic Blood Pressure With the Incidence of Coronary Artery Disease or Cerebrovascular Disease According to Glucose Status2021

    • Author(s)
      Yamada MH, Fujihara K, Kodama S, Sato T, Osawa T, Yaguchi Y, Yamamoto M, Kitazawa M, Matsubayashi Y, Yamada T, Seida H, Ogawa W, Sone H
    • Journal Title

      Diabetes Care

      Volume: 44 Issue: 9 Pages: 2124-2131

    • DOI

      10.2337/dc20-2252

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rates and risk factors for amputation in people with diabetes in Japan: a historical cohort study using a nationwide claims database2021

    • Author(s)
      Kaneko M, Fujihara K, Harada MY, Osawa T, Yamamoto M, Kitazawa M, Matsubayashi Y, Yamada T, Seida H, Kodama S, Sone H
    • Journal Title

      Journal of Foot and Ankle Research

      Volume: 14 Issue: 1 Pages: 29-29

    • DOI

      10.1186/s13047-021-00474-8

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparing Associations of Dietary Energy Density and Energy Intake, Macronutrients with Obesity in Patients with Type 2 Diabetes (JDDM 63)2021

    • Author(s)
      Takeda Y, Fujihara K, Nedachi R, Ikeda I, Morikawa SY, Hatta M, Horikawa C, Kato M, Kato N, Yokoyama H, Kurihara Y, Miyazawa K, Maegawa H, Sone H
    • Journal Title

      Nutrients

      Volume: 13 Issue: 9 Pages: 3167-3167

    • DOI

      10.3390/nu13093167

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Big data and machine learning applications in diabetes care2023

    • Author(s)
      Fujihara K
    • Organizer
      International Congress of Diabetes and Metabolism
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Real-world Data Applications in Glucose Tolerance Status, Obesity and Cardiovascular Disease2023

    • Author(s)
      Fujihara K
    • Organizer
      International Congress on Obesity and MEtabolic Syndrome 2023 (ICOMES 2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Incidence and predictors of remission and relapse of type 2 diabetes mellitus in Japan: Analysis of Nationwide Patient Registry2023

    • Author(s)
      Fujihara K, Khin L, Murai K, Yamazaki Y, Tsuruoka K, Yagyuda N, Yamazaki K, Maegawa H, Tanaka S, Kodama S, Sone H; JDDM Study Group.
    • Organizer
      83rd American Diabetes Association (ADA) Scientific Sessions
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The conflicting significance of high BMI as a predictor of individual diabetic complications2023

    • Author(s)
      Yaguchi Y, Fujihara K, Kobayashi A, Kimura D, Khin L, Wu S, Ferreira Ed, Sato T, Horikawa C, Matsubayashi Y, Kato K, Sone H
    • Organizer
      83rd American Diabetes Association (ADA) Scientific Sessions
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Assessment of a comprehensive physical fitness index to predict future diabetes mellitus (DM) and metabolic syndrome (MetS)2023

    • Author(s)
      Sato T, Fujihara K , Yamada MH , Cho K , Yaguchi Y, Yamamoto M , Kitazawa M , Ishiguro H , Osawa T, Yamada T , Kato K , Sone H
    • Organizer
      83rd American Diabetes Association (ADA) Scientific Sessions
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 耐糖能別おける収縮期血圧(SBP)と心不全発症の関連2023

    • Author(s)
      藤原和哉、小林綾子、山田万祐子、山本正彦、北澤勝、松林泰弘、児玉暁、曽根博仁
    • Organizer
      第33回日本疫学会学術総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 臨床研究で切り開く新しい糖尿病診療2023

    • Author(s)
      藤原和哉
    • Organizer
      第60回日本糖尿病学会関東甲信越地方会
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] リアルワールドデータを活用した糖尿病データ研究2022

    • Author(s)
      藤原和哉
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] Associations of Systolic Blood Pressure (SBP) with the Incidence of Heart Failure (HF) According to Glucose Tolerance Status (GTS)2022

    • Author(s)
      Fujihara K, Yamada M.H, Yamamoto M, Oe M, Osawa T, Iwanaga M, Yamada T, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Plasma hypoxanthine as a potential marker for diabetic kidney disease (DKD) regardless of its subtypes2022

    • Author(s)
      Yamamoto M, Harada S, Okamura T, Fujihara K, Kodama S, Yamada T, Sone H, Takebayashi T. Plasma hypoxanthine as a potential marker for diabetic kidney disease (DKD) regardless of its subtypes
    • Organizer
      58th European Association for the Study of Diabetes (EASD) Annual Meeting
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Association between Screen Time, Including That for Smartphones, and Overweight/Obesity among Children in Japan2022

    • Author(s)
      Ikeda I, Fujihara K, Morikawa S.Y, Takeda Y, Ishiguro H, Yamada M.H, Horikawa C, Matsubayashi Y, Yamada T, Ogawa Y, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Sex Differences in the Effect of High Serum Uric Acid on the Incidence of Vision-Threatening Retinopathy in Those with Type 2 Diabetes2022

    • Author(s)
      Yamamoto M, Fujihara K, Ishiguro H, Yaguchi Y, Ishizawa M, Yamada M.H, Osawa T, Kitazawa M, Kaneko M, Matsubayashi Y, Iwanaga M, Yamada T, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Association between Sleep Duration, Bedtime, and Hyperglycemia or Overweight/Obesity among Japanese Children2022

    • Author(s)
      Shiozaki H, Fujihara K, Yamada M.H, Osawa T, Kitazawa M, Matsubayashi Y, Yaguchi Y, Yamamoto M, Sato t, Yamada T, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of Medication Adherence (MA) to Oral Glycemic Agents (OHAs) on Initiation of Dialysis in Patients with Moderately Impaired Renal Function2022

    • Author(s)
      Yaguchi Y, Fujihara K, Yamada M.H, Matsubayashi Y, Yamada T, Iwanaga M, Kitazawa M, Yamamoto M, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Evaluation of a Comprehensive Physical Fitness Index to Predict Future Prediabetes and Metabolic Syndrome (MetS)2022

    • Author(s)
      Sato T, Fujihara K, Yamada M.H, Cho K, Yaguchi Y, Yamamoto M, Kitazawa M, Ishiguro H, Osawa T, Yamada T, Kato K, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Network Meta-analysis of Hypoglycemic Treatment Regimens with Potential Risk of Hypoglycemia in Terms of Glycemic Control and Severe Hypoglycemia2022

    • Author(s)
      Kodama S, Sato T, Yamada M.H, Yamamoto M, Matsubayashi Y, Ishiguro H, Iwanaga M, Fujihara K, Yamada T, Kato K, Watanabe K, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of Health Factors on Incident Cardiovascular Disease (CVD) According to Glucose Tolerance Status2022

    • Author(s)
      Iijima T, Fujihara K, Yamada M.H, Yamamoto M, Osawa T, Matsubayashi Y, Sato T, Yaguchi Y, Iwanaga M, Yamada T, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Use of American Heart Association’s “Life’s Simple 7” as a Predictor for Initiation of Dialysis2022

    • Author(s)
      Osawa T, Fujihara K, Yamada M.H, Yaguchi Y, Sato T, Kitazawa M, Matsubayashi Y, Yamada T, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] ombined Severe Diabetic Complications: The New Life-Altering Outcome2022

    • Author(s)
      Yaguchi Y, Fujihara K, Yamada M.H, Matsubayashi Y, Yamada T, Iwanaga M, Kitazawa M, Yamamoto M, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of Metabolic Syndrome and Metabolic Dysfunction and Associated Fatty Liver Disease on Cardiovascular Risk in People With and Without Type 2 Diabetes2022

    • Author(s)
      Matsubayashi Y, Fujihara K, Yamada M.H, Yaguchi Y, Yamamoto M, Ishiguro H, Kitazawa M, Iwanaga M, Yamada T, Kodama S, Sone H
    • Organizer
      82nd American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 耐糖能およびHDL-C値によるLDL-C値が冠動脈疾患発症に及ぼす影響の検討2022

    • Author(s)
      山田万祐子、藤原和哉、大澤妙子、北澤勝、松林泰弘、矢口雄大、山本正彦、佐藤隆明、三ツ間友里恵、岩永みどり、山田貴穂、児玉暁、曽根博仁
    • Organizer
      第37回日本糖尿病合併症学会/第28回日本糖尿病眼学会総会
    • Related Report
      2022 Research-status Report
  • [Presentation] HDLコレステロール値別にみたLDLコレステロールと冠動脈疾患との関連2022

    • Author(s)
      山田万祐子、藤原和哉、大澤妙子、北澤勝、松林泰弘、矢口雄大、山本正彦、佐藤隆明、三ッ間友里恵、岩永みどり、山田貴穂、児玉暁、曽根博仁
    • Organizer
      第95回日本内分泌学会学術総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 肥満の有無による脂肪肝(MAFLD)が心血管疾患発症に与える影響の違い2022

    • Author(s)
      松林泰弘、藤原和哉、山田万祐子、曽根博仁
    • Organizer
      第95回日本内分泌学会学術総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 小児における睡眠時間およびソーシャルジェットラグと過体重・肥満の関連2022

    • Author(s)
      塩﨑悠香、藤原和哉、山田万祐子、大澤妙子、北澤勝、松林泰弘、矢口雄大、山本正彦、佐藤隆明、山田貴穂、曽根博仁
    • Organizer
      第95回日本内分泌学会学術総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 青少年におけるスマートフォンを含むスクリーンタイムと肥満との関連2022

    • Author(s)
      池田和泉、藤原和哉、森川咲子、武田安永、石黒創、山田万祐子、堀川千嘉、松林泰弘、山田貴穂、曽根博仁
    • Organizer
      第95回日本内分泌学会学術総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 日本人2型糖尿病患者における食品群摂取量と肥満の関連-JDDMにおける検討2022

    • Author(s)
      治田麻理子、堀川千嘉、武田安永、池田和泉、森川咲子、加藤則子、加藤光敏、横山宏樹、栗原義夫、前川聡、藤原和哉、曽根博仁、JDDMグループ
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] AHA Life’s simple 7に基づく腎透析導入リスクの予測2022

    • Author(s)
      大澤妙子、藤原和哉、山田万祐子、矢口雄大、佐藤隆明、北澤勝、松林泰弘、山田貴穂、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 肥満における各野菜摂取頻度と遺伝子・環境相互作用の検討2022

    • Author(s)
      藤原和哉、野川駿、齋藤憲司、堀川千嘉、武田安永、張かおり、石黒創、児玉暁、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 耐糖能およびHDLコレステロール値別にみたLDLコレステロールが冠動脈疾患に及ぼす影響の検討2022

    • Author(s)
      山田万祐子、藤原和哉、大澤妙子、北澤勝、松林泰弘、矢口雄大、山本正彦、佐藤隆明、三ッ間友里恵、岩永みどり、山田貴穂、児玉暁、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 経口血糖降下薬(OHA)の服用アドヒアランス(Ad)および血糖コントロールと細小/大血管合併症発症の縦断的検討2022

    • Author(s)
      矢口雄大、藤原和哉、山田万祐子、北澤勝、山本正彦、松林泰弘、児玉暁、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 2型糖尿病の有無別のmetabolic syndrome, metabolic dysfunction-associated fatty liver diseaseが心血管疾患に与える影響2022

    • Author(s)
      松林泰弘、藤原和哉、山田万祐子、矢口雄大、山本正彦、石黒創、北澤勝、岩永みどり、山田貴穂、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 妊娠中期における糖代謝状態と低出生体重児出産との関連の検討2022

    • Author(s)
      谷内洋子、山田貴穂、藤原和哉、生魚薫、堀川千嘉、田中康弘、瀧野一郎、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 食事摂取量及び身体活動量の変化に応じたSGLT2阻害薬及びDPP4阻害薬の血糖コントロールの改善度の比較-NISM-Study post-hoc解析2022

    • Author(s)
      38.北澤勝、片桐尚、鈴木裕美、松永佐澄志、山田万祐子、五十嵐智雄、山本正彦、古川和郎、岩永みどり、治田麻理子、藤原和哉、山田貴穂、田中司朗、曽根博仁
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 耐糖能別における収縮期血圧と冠動脈疾患(CAD)/脳血管疾患発症(CVD)の関連2022

    • Author(s)
      藤原和哉、山田万祐子、山本正彦、松林泰弘、北澤勝、石澤正博、堀川千嘉、児玉暁、曽根博仁
    • Organizer
      第32回日本疫学会学術総会
    • Related Report
      2021 Research-status Report
  • [Presentation] Can Machine Learning Support Decision for Insulin Initiation in Patients with Type 2 Diabetes?2021

    • Author(s)
      Fujihara K, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Poor Adherence to Medication and High HbA1c Predict Risk of Amputation in Diabetes Mellitus: Historical Cohort Study Using a Nationwide Claims Database2021

    • Author(s)
      Kaneko M, Fujihara K, Yamada HM, Yaguchi Y, Yamamoto M, Kitazawa M, Kodama M, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Association between Estimated Glomerular Filtration Rate (eGFR) and Proteinuria (UP) to Predict Risk of Start of Dialysis in People with and without Diabetes (DM)2021

    • Author(s)
      OsaswaT, Fujihara K, Yamada HM, Yaguchi Y, Sato T, Kitazawa M, Matsubayashi Y, Yamada T, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Utility of a Comprehensive Physical Fitness Score by the Tests of Physical Fitness in Screening of Metabolic Diseases2021

    • Author(s)
      Sato T, Fujihara K, Yamada HM, Yaguchi Y, Kitazawa M, Yamamoto M, Kodama S, Kato K, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Association between Glucose Abnormality Status and Previous Cerebrovascular Disease (CVD) on Subsequent CVD in Japanese Men Using Real-World Data2021

    • Author(s)
      Oe M, Fujihara K, Yamada HM, Osawa T, Kitazawa M, Matsubayashi Y, Sato T, Yaguchi Y, Iwanaga M, Yamada T, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Large Quantity of Alcohol Intake per Occasion was Positively Associated with Vision-Threatening Eye Diseases in Japanese Men with Type 2 Diabetes2021

    • Author(s)
      Yamamoto M, Fujihara K, Yaguchi Y, Osawa T, Kaneko M, Kitazawa M, Sato T, Yamada HM, Matsubayashi Y, Yamada T, Kodama S, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of Medication Adherence and Glycemic Control on the Risk of Micro/Macrovascular Diseases in Patients with Diabetes2021

    • Author(s)
      Yaguchi Y, Fujihara K, Yamada HM, Matsubayashi Y, Yamada T, Iwanaga M, Kitazawa M, Yamamoto M, Kodama S, Sone H
    • Organizer
      81st American Diabetes Association Scientific Sessions (ADA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] アルクールドデータを活用した糖尿病合併症研究2021

    • Author(s)
      藤原和哉
    • Organizer
      第6回日本糖尿病・生活習慣病ヒューマンデータ学会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 耐糖能および脳血管疾患の既往とその組み合わせがその後の脳血管疾患発症に与える影響2021

    • Author(s)
      大江桃子,藤原和哉他
    • Organizer
      第6回日本糖尿病・生活習慣病ヒューマンデータ学会
    • Related Report
      2021 Research-status Report
  • [Presentation] 経口血糖降下薬(OHA)の服薬アドヒアランスおよび血糖コントロールと細小/大血管合併症発症の関連の検討2021

    • Author(s)
      矢口雄大,藤原和哉他
    • Organizer
      第6回日本糖尿病・生活習慣病ヒューマンデータ学会
    • Related Report
      2021 Research-status Report
  • [Presentation] 耐糖能別における収縮期血圧と冠動脈疾患/脳血管疾患発症の関連2021

    • Author(s)
      藤原和哉、山田万祐子、大江桃子、山本正彦、北澤勝、松林泰弘、児玉暁、曽根博仁
    • Organizer
      第53回日本動脈硬化学会総会・学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 経口血糖降下薬 (OHA) の服薬アドヒアランスおよび血糖コントロールと細小/大血管合併症発症の関連の検討2021

    • Author(s)
      矢口雄大、藤原和哉、山田万祐子、北澤勝、山本正彦、松林泰弘、児玉暁、曽根博仁
    • Organizer
      第36回日本糖尿病合併症学会・第27回日本糖尿病眼学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 日本人男性における耐糖能別にみた脳卒中既往がその後の脳卒中発症に与える影響2021

    • Author(s)
      山田万祐子、藤原和哉、大江桃子、大澤妙子、北澤勝、松林泰弘、佐藤隆明、矢口雄大、岩永みどり、山田貴穂、曽根博仁
    • Organizer
      第36回日本糖尿病合併症学会・第27回日本糖尿病眼学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 糖尿病(DM)の有無別にみたeGFRと尿蛋白が透析開始に及ぼす影響2021

    • Author(s)
      大澤妙子、藤原和哉、山田万祐子、山本正彦、矢口雄大、北澤勝、松林泰弘、山田貴穂、曽根博仁
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 健診の体力テスト結果を用いた総合体力指標の算出と生活習慣病との関連の検討2021

    • Author(s)
      佐藤隆明、藤原和哉、矢口雄大、山田万祐子、北澤勝、山本正彦、松林泰弘、岩永みどり、山田貴穂、加藤公則、曽根博仁
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 機械学習による糖尿病専門医のインスリン選択の予測能の検討及び一般医との比較検討2021

    • Author(s)
      藤原和哉、松林泰弘、山田万祐子、山本正彦、飯塚敏浩、宮村幸祐、長谷川好範、山本寛悟、前川聡、山﨑達也、曽根博仁
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 日本人男性における耐糖能と脳卒中既往がその後の脳卒中発症に与える影響-リアルワールドデータによる検討2021

    • Author(s)
      山田万祐子、藤原和哉、大江桃子、大澤妙子、北澤勝、松林泰弘、佐藤隆明、矢口雄大、岩永みどり、清田浩康、山田貴穂、曽根博仁
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 経口血糖降下薬(OHA)の服薬アドヒアランス(Ad)と生活習慣因子の関連2021

    • Author(s)
      矢口雄大、藤原和哉、山田万祐子、北澤勝、金子正儀、清田浩康、松林泰弘、曽根博仁
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report

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Published: 2021-04-28   Modified: 2025-01-30  

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