Mechanisms of vascular pattern formation through multiple intercellular communication molecules

• Project/Area Number: 21K15123
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 44030:Plant molecular biology and physiology-related
• Research Institution: Osaka University
• Principal Investigator: 銭 平平 大阪大学, 理学研究科, 助教 (20840466)
• Project Period (FY): 2021-04-01 – 2023-03-31
• Project Status: Granted (Fiscal Year 2021)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2022: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2021: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: peptide / receptor / transcription factor / vasculature / phloem

Outline of Research at the Start

Regulatory mechanisms of phloem development and patterning are being uncovered, but are still only partially known. Here, we hypothesize that there are positive feedback mechanisms that reinforce the Phloem-Dofs expression during phloem development. Our preliminary results showed that Phloem-Dofs induce several positive regulators, including plant hormones and secretory peptides.I will uncover the integrated intracellular and intercellular signaling systems that create the proper vascular pattern, with emphasis on phloem.