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Investigating factors of oral function decline in the elderly through long-term longitudinal study

Research Project

Project/Area Number 21K17038
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionOsaka University

Principal Investigator

Mihara Yusuke  大阪大学, 大学院歯学研究科, 助教 (30779096)

Project Period (FY) 2021-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2022: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2021: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords咀嚼能力 / 臼歯部咬合支持 / 高齢者 / 口腔機能 / 咬合力 / 舌圧 / 一般化線形混合モデル
Outline of Research at the Start

本研究の目的は、多人数の高齢者を対象に調査を行い、追跡調査から得られたデータを用いて、口腔衛生状態、口腔乾燥、咬合力、舌口唇運動機能、舌圧、咀嚼機能、嚥下機能といった口腔機能ごとの低下に関連する因子を探索するとともに、性別、年代、歯数別の関連因子の違いや低下パターンの違いを検討することである。

Outline of Final Research Achievements

The subjects were 488 of the 864 participants in the SONIC study, aged 72-74 years, who were followed up. Participants were divided into three groups according to the number of occlusal supports in the left and right premolars and molars. The relationship between occlusal support and masticatory ability was analyzed longitudinally using a linear mixed-effects model. The results showed that gender, occlusal force, number of unprostained missing teeth, aging, and changes in molar occlusal support were significantly associated with masticatory ability. Furthermore, the interaction term between change in molar occlusal support and aging was a significant explanatory variable for decreased masticatory ability. These results indicate that loss of molar occlusal support is a major factor in the decline of masticatory ability.

Academic Significance and Societal Importance of the Research Achievements

咬合支持の喪失は、咀嚼能力の低下に関連すると考えられている。しかしながら、これまでの先行研究は、横断的研究に基づくものであった。そこで、本研究では、地域在住の高齢者の咬合支持の変化と咀嚼能力との関連を縦断的に検討した。
その結果、臼歯部咬合支持の喪失は、咀嚼能力低下に関連することが明らかとなり、高齢者の咀嚼能力維持には、臼歯部咬合支持の喪失予防が重要であることが示唆された。臼歯部咬合支持を維持することは、食物摂取の多様性と栄養状態の維持に寄与し、高齢者のQOLを向上させると考えられる。歯科医療従事者は、臼歯部咬合咬合支持崩壊のリスクを評価するために、歯の状態を注意深く検査する必要がある。

Report

(4 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (10 results)

All 2024 2023 2022 2021

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (6 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Factors related to subjective evaluation of difficulty in chewing among community-dwelling older adults.2024

    • Author(s)
      Seto E, Kosaka T, Hatta K, Mameno T, Mihara Y, Fushida S, Murotani Y, Maeda E, Akema S, Takahashi T, Wada M, Gondo Y, Masui Y, Ishizaki T, Kamide K, Kabayama M, Ikebe K
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 1 Issue: S1 Pages: 327-333

    • DOI

      10.1111/ggi.14783

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The relationship between changes in occlusal support and masticatory performance using 6-year longitudinal data from the SONIC study2023

    • Author(s)
      Higashi K, Hatta K, Mameno T, Takahashi T, Gondo Y, Kamide K, Masui Y, Ishizaki T, Arai Y, Kabayama M, Nishimura Y, Murotani Y, Hagino H, Tsujioka Y, Akema S, Maeda E, Seto E, Okada Y, Mihara Y, Wada M, Maeda Y, Ikebe K
    • Journal Title

      Journal of Dentistry

      Volume: 139 Pages: 104763-104763

    • DOI

      10.1016/j.jdent.2023.104763

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predictive factors for tooth loss in older adults vary according to occlusal support: A 6-year longitudinal survey from the SONIC study2022

    • Author(s)
      Hitomi S, Hatta K, Murotani Y, Takahashi T, Gondo Y, Kamide K, Masui Y, Ishizaki T, Kabayama M, Ogata S, Matsuda K, Mihara Y, Fukutake M, Hagino H, Higashi K, Akema S, Kitamura M, Murakami S, Maeda Y, Ikebe K.
    • Journal Title

      Journal of Dentistry

      Volume: - Pages: 104088-104088

    • DOI

      10.1016/j.jdent.2022.104088

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Decline of oral functions in old‐old adults and their relationship with age and sex: The SONIC study2021

    • Author(s)
      Hatta Kodai、Murotani Yuki、Takahashi Toshihito、Gondo Yasuyuki、Kamide Kei、Masui Yukie、Ishizaki Tatsuro、Ogata Soshiro、Matsuda Ken‐ichi、Mihara Yusuke、Fukutake Motoyoshi、Nishimura Yuichi、Hagino Hiromasa、Higashi Kotaro、Maeda Yoshinobu、Ikebe Kazunori
    • Journal Title

      Journal of the American Geriatrics Society

      Volume: 70 Issue: 2 Pages: 541-548

    • DOI

      10.1111/jgs.17535

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Decrease in posterior occlusal support affects the progression of atherosclerosis among community-dwelling older adults2023

    • Author(s)
      Seto E, Kosaka T, Kamide K, Gondo Y, Kabayama M, Godai K, Kido M, Akasaka H, Yamamoto K, Ishizaki T, Arai Y, Masui Y, Takahashi T, Mameno T, Mihara Y, Murotani Y, Tsujioka Y, Akema S, Okada Y, Ikebe K
    • Organizer
      ECG Annual Congress Stockholm 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Oral function was associated with the risk of oral frailty and the need for nursing care in a longitudinal study of Japanese older adults2023

    • Author(s)
      Murotani Y,Mihara Y,Takahashi T,Hatta K,Matsuda K,Higashi K,Hagino H,Kimura A,Enoki K,Maeda Y,Ikebe K
    • Organizer
      ECG Annual Congress Stockholm 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Causal relationships between cognitive decline and oral factors revealed by structural equation models2023

    • Author(s)
      Higashi K, Takahashi T, Mameno T, Nozaki K, Hatta K, Murotani Y, Tsujioka Y, Akema S, Seto E, Okada Y, Takeuchi S, Mihara Y, Wada M, Maeda Y, Ikebe K
    • Organizer
      ECG Annual Congress Stockholm 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 食品のかみにくさの自覚に関連する因子2022

    • Author(s)
      前田絵里紗,八田昂大,髙橋利士,豆野智昭,福武元良,西村優一,室谷有紀,萩野弘将,辻岡義祟,東孝太郎.明間すずな,三原佑介,和田誠大,前田芳信,池邉一典
    • Organizer
      第131回日本補綴歯科学会学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 超高齢者の口腔健康と幸福感との関連の検討2022

    • Author(s)
      能勢 彩花、八田 昂大、高橋 利士、豆野 智昭、福武 元良、西村 優一、室谷 有紀、萩野 弘将、 辻岡 義崇、明間 すずな、三原 佑介、和田 誠大、前田 芳信、池邉 一典
    • Organizer
      第33回日本老年歯科医学会学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 3年間の縦断研究による口腔機能の加齢による影響の検討2021

    • Author(s)
      室谷有紀,八田昂大,三原佑介,福武元良,佐藤仁美,萩野弘将,東孝太郎,高橋利士,松田謙一,前田芳信,池邉一典
    • Organizer
      老年歯科医学会 第32回学術大会
    • Related Report
      2021 Research-status Report

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Published: 2021-04-28   Modified: 2025-01-30  

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