A Multifaceted Study for Determining Effective Mental Practice Intensity from a Fatigue Perspective

• Project/Area Number: 21K17513
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59010:Rehabilitation science-related
• Research Institution: Nagasaki University
• Principal Investigator: NAKASHIMA Akira 長崎大学, 医歯薬学総合研究科(保健学科), 客員研究員 (90897349)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2023: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2022: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2021: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: メンタルプラクティス / 疲労 / TMS / メンタルプラクティス（運動イメージトレーニング） / 脳卒中後麻痺側上肢機能 / 方法論 / ＴＭＳ

Outline of Research at the Start

本研究では脳卒中後の運動麻痺に対する介入方法の一つであるメンタルプラクティスの効果的な負荷量の決定に向け，メンタルプラクティスに伴い出現する疲労が皮質脊髄路の興奮性や運動課題遂行能力の向上に及ぼす影響を多面的に検討する．

Outline of Final Research Achievements

The purpose of this study was to investigate the effects of fatigue that emerges as the number of motor imagery (MI) repetitions increases on corticospinal tract excitability and motor task performance, and to determine the effective number of MI repetitions (intensity) in mental practice. The results of this study revealed that mental practice causes mental fatigue through continuous repetition of MIs and affects performance improvement in the same way as physical training. Careful consideration should be given when implementing mental practice in clinical practice, as the fatigue associated with continuous repetition of MI may have a negative impact on performance improvement.

Academic Significance and Societal Importance of the Research Achievements

メンタルプラクティスは効果的な介入方法であることが示されているが，その実施においては介入時間，介入頻度，介入期間といった方法論に明確な基準は無く，実施者の主観に委ねられている状況である．その中で本研究は，メンタルプラクティスの介入時間（負荷量）に着目した研究であり，その成果は今後の方法論の確立に大きな一助を成すことが出来るのではないかと考える．脳卒中後の運動麻痺に対するリハビリテーションの発展は，対象者の日常生活能力やQOLの向上に寄与するものであると考える．

Research Products

• [Journal Article] Exploring Methodological Issues in Mental Practice for Upper-Extremity Function Following Stroke-Related Paralysis: A Scoping Review (2024)
  • Author(s): Nakashima Akira、Okamura Ryohei、Moriuchi Takefumi、Fujiwara Kengo、Higashi Toshio、Tomori Kounosuke
  • Journal Title: Brain Sciences Volume: 14 Issue: 3 Pages: 202-202
  • DOI: 10.3390/brainsci14030202
  • Peer Reviewed / Open Access
• [Journal Article] Effects of a virtual reality-based mirror therapy system on upper extremity rehabilitation after stroke: a systematic review and meta-analysis of randomized controlled trials (2024)
  • Author(s): Ryohei Okamura 1, Akira Nakashima Takefumi Moriuchi, Kengo Fujiwara, Kanta Ohno, Toshio Higashi, Kounosuke Tomori
  • Journal Title: Frontirrs in Neulology Volume: 14:1298291 Pages: 1-10
  • DOI: 10.3389/fneur.2023.1298291
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy of mental practice on paralyzed upper extremity function in the acute phase of stroke: a case study (2024)
  • Author(s): Akira Nakashima, Tetsuji Koizumi, Tadashi Shimizu, Nobutoshi Ryu, Toshio Higashi
  • Journal Title: Journal of Physical Therapy Science Volume: -
  • Peer Reviewed / Open Access
• [Journal Article] Comparing movement-related cortical potential between real and simulated movement tasks from an ecological validity perspective (2023)
  • Author(s): Kakuya Ogahara, Akira Nakashima, Tomotaka Suzuki, Kenichi Sugawara, Naoshin Yoshida, Arihiro Hatta, Takefumi Moriuchi, Toshio Higashi
  • Journal Title: Front Hum Neurosci Volume: 17 Pages: 1313835-1313835
  • DOI: 10.3389/fnhum.2023.1313835
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy of combined hand exercise intervention in patients with chemotherapy-induced peripheral neuropathy: a pilot randomized controlled trial (2022)
  • Author(s): Ikio Yuta、Sagari Akira、Nakashima Akira、Matsuda Daiki、Sawai Terumitsu、Higashi Toshio
  • Journal Title: Supportive Care in Cancer Volume: 30 Issue: 6 Pages: 4981-4992
  • DOI: 10.1007/s00520-022-06846-5
  • Peer Reviewed / Open Access
• [Journal Article] Continuous Repetition Motor Imagery Training and Physical Practice Training Exert the Growth of Fatigue and Its Effect on Performance (2022)
  • Author(s): Akira Nakashima, Takefumi Moriuchi, Daiki Matsuda, Jirou Nakamura, Kengo Fujiwara, Yuta Ikio, Takashi Hasegawa, Wataru Mitunaga, Toshio Higashi
  • Journal Title: Brain Science Volume: 12 Issue: 8 Pages: 1087-1087
  • DOI: 10.3390/brainsci12081087
  • Peer Reviewed / Open Access
• [Journal Article] Effects of attentional bias modification on chronic low back pain in older outpatients (2021)
  • Author(s): Hasegawa Takashi、Nishi Keita、Nakashima Akira、Moriuchi Takefumi、Iso Naoki、Koseki Hironobu、Tabira Takayuki、Higashi Toshio
  • Journal Title: Medicine Volume: 100 Issue: 45 Pages: e27738-e27738
  • DOI: 10.1097/md.0000000000027738
  • NAID: 120007190852
  • Peer Reviewed / Open Access
• [Journal Article] A method for using video presentation to increase the vividness and the activity of cortical regions during motor imagery tasks. (2021)
  • Author(s): Kengo Fujiwara, Masakazu Shibata, Yoshinaga Awano, Koji Shibayama, Naoki Iso, Moemi Matsuo, Akira Nakashima, Takefumi Moriuchi, Wataru Mitsunaga, Toshio Higashi
  • Journal Title: Neural Regeneration Research Volume: 16 Issue: 12 Pages: 2431-2437
  • DOI: 10.4103/1673-5374.313058
  • Peer Reviewed / Open Access
• [Presentation] 慢性腰痛を有する外来通院高齢者に対する注意バイアス修正法を用いた介入効果 (2023)
  • Author(s): 長谷川 隆史, 西 啓太, 森内 剛史, 松本 伸一, 永江 槙一, 中島 輝, 東 登志夫
  • Organizer: 日本ペインリハビリテーション学会
• [Presentation] 脳卒中後の上肢機能障害に対するVirtual Reality-based Mirror Therapyの効果 システマティックレビュー & メタアナリシスによる検討 (2023)
  • Author(s): 岡村諒平, 中島輝, 森内剛史, 藤原謙吾, 大野勘太, 東登志夫, 友利幸之介
  • Organizer: 日本作業療法研究学会学術大会
• [Presentation] 脳卒中後麻痺側上肢機能に対するメンタルプラクティスの方法論に関するスコーピングレビュー (2023)
  • Author(s): 中島輝, 岡村諒平, 藤原謙吾, 森内剛史, 友利幸之介, 東登志夫
  • Organizer: 日本作業療法研究学会学術大会