| Budget Amount *help |
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2023: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2022: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2021: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Based on the genetic analysis of Rhodococcus erythropolis, there seems to be a novel pheromone-like biologically active compound in Rhodococcus erythropolis. We first established a bioassay system using gene disruption strains and searched for the pheromone-like biologically active compound. The morphological change inducers were found in the culture medium of the wild strain, which changed the shape of the disrupted strain from clumped colonies to a floating and turbid form, similar to the wild strain. However, the morphology change inducer was unstable and could not be purified or structurally determined.
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