Epigenetic Regulation of Adipocyte Progenitor Cells
| Project/Area Number |
21K19499
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Review Section |
Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
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| Research Institution | Akita University |
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Principal Investigator |
Waki Hironori 秋田大学, 医学系研究科, 教授 (00466765)
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| Project Period (FY) |
2021-07-09 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2022: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2021: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 脂肪細胞 |
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| Outline of Research at the Start |
最新のシングルセル解析やリニエージ解析からの新知見で明らかになった生体内の新規脂肪前駆細胞群の定常状態および環境応答・病態による変動の解明にエピゲノム解析を応用し、その制御因子と制御機構を明らかにする。
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| Outline of Final Research Achievements |
The aim is to elucidate regulatory mechanism that controls adipocyte progenitor cells in adipose tissue that were newly identified by recent single cell analyses and lineage analyses. We conducted flowcytometry and epigenetic analyses on adipocyte progenitor cells in adipose tissue and identified a subset of progenitor cells that have new characteristics.
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| Academic Significance and Societal Importance of the Research Achievements |
新知見で明らかになった生体内の脂肪細胞に分化する前駆細胞群について解析を応用し、その制御機構を明らかにする目的で、脂肪組織内の前駆細胞の解析を施行し新たな性質を有する脂肪前駆細胞の一群を見出した。
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Report
(2 results)
Research Products
(7 results)
