• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Do lethal infectious diseases invade into endangered species in Nepal? - Conservation science in biodiversity hotspot -

Research Project

Project/Area Number 21KK0120
Research Category

Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Research InstitutionHokkaido University

Principal Investigator

Tsubota Toshio  北海道大学, 獣医学研究院, 教授 (10207441)

Co-Investigator(Kenkyū-buntansha) THAPA JEEWAN  北海道大学, 人獣共通感染症国際共同研究所, 助教 (40837449)
大沼 学  国立研究開発法人国立環境研究所, 生物多様性領域, 室長 (50442695)
鍋島 圭  国立研究開発法人国立環境研究所, 生物多様性領域, 研究員 (70910397)
鈴木 定彦  北海道大学, 人獣共通感染症国際共同研究所, 教授 (90206540)
Project Period (FY) 2021-10-07 – 2025-03-31
Project Status Completed (Fiscal Year 2024)
Budget Amount *help
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2023: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2022: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Fiscal Year 2021: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Keywordsアジアゾウ / ナマケグマ / ツキノワグマ / ヒグマ / 結核 / 分布 / 地球温暖化 / 生息地 / ネパール / 感染症 / 生態 / カメラトラップ / 生物多様性 / 希少種 / 致死感染症 / 生物多様性ホットスポット / 保全科学 / 絶滅リスク評価
Outline of Research at the Start

ネパールは、低緯度地帯ながら北に8,000m級のヒマラヤ山脈が連なり、多様な生態系を擁する生物多様性の宝庫であり、生物多様性ホットスポットに認定されている。亜熱帯域から高山帯域まで様々な生態系に野生動物が生息しているが、その多くは絶滅に瀕している。アジアゾウ、インドサイ、ベンガルトラ、ナマケグマなど、世界的にみて貴重な生態系の要をなす大型哺乳動物の存在が危ぶまれている。本研究では、アジアの生物多様性ホットスポットの一つであるネパールにおいて、絶滅に瀕する希少動物に致死感染症が侵淫しているか、既に侵淫している場合にはその程度(感染率)および伝播ルートを明らかにし、保全科学研究を押し進める。

Outline of Final Research Achievements

In this study, we conducted research into the tuberculosis infection and ecology of Asian elephants and three species of bear including sloth bears, black bears and brown bears, all of which are endangered in the wild in Nepal, respectively. Firstly, with regard to tuberculosis infection in Asian elephants, we performed post-mortem examinations on nine captive Asian elephants that died between 2019 and 2022. We cultured lung lesions to detect Mycobacterium tuberculosis DNA using the LAMP and PCR methods and identified tuberculosis in six and five out of the nine animals, respectively. Secondly, in a study on the ecology of the three bear species, we used a model to predict their future distribution in the lowlands, central hills and high mountains of Nepal based on habitat location and environmental data for each species.

Academic Significance and Societal Importance of the Research Achievements

近年アジアのみならず世界的に問題となっているゾウにおける結核感染症の実態について、ネパールでの状況を示すことができたことは学術的にも社会的にもインパクトの強い成果である。現時点では、飼育下アジアゾウでのみ結核感染症が見つかっているが、野生個体にも感染するおそれがあり、その検出法として糞を使った方法が確立すればより応用範囲が広がると考えられる。クマ3種については、いずれもネパールでは絶滅危惧種にリストアップされており、その生態や生息状況の把握は急務となっている。その中で、今回の研究成果は重要な内容を提示するものである。本研究が基盤となって、さらにこの分野の研究が進展することが望まれている。

Report

(5 results)
  • 2024 Annual Research Report   Final Research Report ( PDF )
  • 2023 Research-status Report
  • 2022 Research-status Report
  • 2021 Research-status Report
  • Research Products

    (16 results)

All 2024 2023 2022 2021 Other

All Int'l Joint Research (2 results) Journal Article (4 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (7 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results) Remarks (2 results) Funded Workshop (1 results)

  • [Int'l Joint Research] National Trust for Nature Conservation/Germany-Nepal Tuberculosis Project(ネパール)

    • Related Report
      2022 Research-status Report
  • [Int'l Joint Research] National Trust for Nature Conservation/Germany-Nepal Tuberculosis Project(ネパール)

    • Related Report
      2021 Research-status Report
  • [Journal Article] Epidemiology and molecular characterization of Mycobacterium tuberculosis including a drug-resistant strain associated with mortality of Asian elephants in Nepal 2019-20222024

    • Author(s)
      Pandit, A., Thapa, J., Sadaula, A., Suzuki, Y., Nakajima, C., Mikota, S. K., Subedi, N., Shretha, B. K., Shimozuru, M., Shrestha, B., Raya, B., Chaudhary, S., Paudel, S. & Tsubota, T.
    • Journal Title

      Tuberculosis

      Volume: 148 Pages: 102550-102550

    • DOI

      10.1016/j.tube.2024.102550

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Predicting the potential habitat of bears under a changing climate in Nepal2024

    • Author(s)
      Baral, R., Adhikari, B., Paudel, R. P., Kadariya, R., Subedi, N., Dhakal, B. K., Shimozuru, M. & Tsubota, T.
    • Journal Title

      Environ. Monit. Assess.

      Volume: 196 Issue: 11 Pages: 1097-1097

    • DOI

      10.1007/s10661-024-13253-2

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Habitat occupancy of sloth bear Melursus ursinus in Chitwan National Park, Nepal2022

    • Author(s)
      Paudel RP, Kadariya R, Lamichhane BR, Subedi N, Sashika M, Shimozuru M, Tsubota T
    • Journal Title

      Ecology and Evolution

      Volume: 12 Issue: 3

    • DOI

      10.1002/ece3.8699

    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 野生動物とワンヘルスそして新型コロナウイルス感染症2022

    • Author(s)
      坪田敏男
    • Journal Title

      大阪保険医雑誌

      Volume: 2 Pages: 9-13

    • Related Report
      2021 Research-status Report
  • [Presentation] Predicting the potential habitat of bears under a changing climate in Nepal2024

    • Author(s)
      Baral,R., Paudel, R. P., Achikari, B., Kadariya, R., Subedi, N., Dhakal, B. K., Shimozuru, M., Tsubota, T.
    • Organizer
      28th International Bear Association Conference
    • Related Report
      2024 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ネパールにおけるアジアゾウへの結核症の脅威2024

    • Author(s)
      坪田敏男
    • Organizer
      第30回日本野生動物医学会大会
    • Related Report
      2024 Annual Research Report
  • [Presentation] ネパールのクマ:現状と人間-野生動物間の対立のダイナミクス2024

    • Author(s)
      Baral, R., Paudel, P. P., Kadariya, R., Subedi, N., Shimozuru, M. & Tsubota, T.
    • Organizer
      第30回日本野生動物医学会大会
    • Related Report
      2024 Annual Research Report
  • [Presentation] ネパールにおけるクマ3種の生態と温暖化による影響2024

    • Author(s)
      坪田敏男
    • Organizer
      日本哺乳類学会2024年度大会
    • Related Report
      2024 Annual Research Report
  • [Presentation] Ecology and genetic diversity of Sloth bear (Melursus ursinus) in Nepal2021

    • Author(s)
      Paudel RP, Shimozuru M, Kadriya R, Subedi N, Sashika M, Tsubota T
    • Organizer
      The 27th International Bear Association Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Habitat occupancy of sloth bears in Chitwan National Park, Nepal2021

    • Author(s)
      Paudel RP, Kadariya R, Lamichhane B, Subedi N, Shimozuru M, Sashika M, Tsubota T
    • Organizer
      The 14th Asian Society of Conservation Medicine/The 27th Japanese Society of Zoo and Wildlife Medicine 2021 Joint Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] One Health approach - Disease ecology in Hokkaido wildlife2021

    • Author(s)
      Tsubota T
    • Organizer
      The 2nd International Conference on Tropical Wetland Biodiversity and Conservation (ICWEB) 2021
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Remarks] 野生動物学教室 研究業績

    • URL

      https://wildlife.vetmed.hokudai.ac.jp/achievements.html

    • Related Report
      2024 Annual Research Report
  • [Remarks] 北海道大学大学院獣医学研究院野生動物学教室

    • URL

      http://wildlife.vetmed.hokudai.ac.jp/

    • Related Report
      2022 Research-status Report 2021 Research-status Report
  • [Funded Workshop] Nepal Bear Workshop2023

    • Related Report
      2023 Research-status Report

URL: 

Published: 2021-10-22   Modified: 2026-01-16  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi