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Development of Micro Arrays for Analyzing Small RNAs

Research Project

Project/Area Number 22225003
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Analytical chemistry
Research InstitutionTohoku University

Principal Investigator

TERAMAE Norio  東北大学, 理学(系)研究科(研究院), 名誉教授 (70114569)

Co-Investigator(Kenkyū-buntansha) YAMAGUCHI Akira  茨城大学, 理学部, 准教授 (10359531)
NISHIZAWA Seiichi  東北大学, 大学院理学研究科, 教授 (40281969)
SATO Yusuke  東北大学, 大学院理学研究科, 助教 (90583039)
XU Zhiai  東北大学, 大学院理学研究科, 助教 (50562336)
Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥216,320,000 (Direct Cost: ¥166,400,000、Indirect Cost: ¥49,920,000)
Fiscal Year 2013: ¥31,980,000 (Direct Cost: ¥24,600,000、Indirect Cost: ¥7,380,000)
Fiscal Year 2012: ¥57,850,000 (Direct Cost: ¥44,500,000、Indirect Cost: ¥13,350,000)
Fiscal Year 2011: ¥51,870,000 (Direct Cost: ¥39,900,000、Indirect Cost: ¥11,970,000)
Fiscal Year 2010: ¥74,620,000 (Direct Cost: ¥57,400,000、Indirect Cost: ¥17,220,000)
Keywords化学センサー / バイオセンサー / 蛍光性リガンド / 核酸 / ナノ細孔 / 過冷却 / 小分子RNA / 拡散 / miRNA / 蛍光リガンド / 光導波路
Outline of Final Research Achievements

This work aimed to develop new strategy of small RNA analysis based on the RNA-binding fluorescent ligands in confined nanopores. Toward this end, we focused on the design of fluorescent abasic site (AP site)-bidning ligands (APLs) in RNA or DNA/RNA duplexes. We successfully found useful G, C, A, or U-discriminating candidates targeting the duplexes. Moreover, new class of light-up fluorescent ligands was developed based on the conjugation of APLs with cyanine dyes. On the other hand, we revealed several unique features of confined spaces inside the silica and alumina nanopores. Especially, exothermic reactions such as cyclodextrin inclusion and DNA hybridization were found to be accelerated inside the nanopores under supercooled condition. Finally, we found possible applications to detect dozens of attomole nucleic acids and analyze their sequences with single nucleotide resolution by the binding of APL-cyanine dye conjugates inside the confined nanopores under supercooled conditions.

Assessment Rating
Verification Result (Rating)

A

Report

(6 results)
  • 2015 Research Progress Assessment (Verification Result) ( PDF )
  • 2014 Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (224 results)

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article (32 results) (of which Peer Reviewed: 31 results,  Open Access: 11 results,  Acknowledgement Compliant: 9 results) Presentation (192 results) (of which Invited: 30 results)

  • [Journal Article] Synthetic fluorescent probes capable of selective recognition of 3'-overhanging nucleotides for siRNA delivery imaging2015

    • Author(s)
      T. Sato, Y. Sato, K. Iwai, S. Kuge, S. Nishizawa, N. Teramae
    • Journal Title

      Chem. Commun.

      Volume: 15 Issue: 8 Pages: 1421-1424

    • DOI

      10.1039/c4cc08800j

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A label-free and sensitive fluorescent method for the detection of uracil-DNA glycosylase activity2015

    • Author(s)
      J. Tao, P. Song, Y. Sato, S. Nishizawa, N. Teramae, A. Tong, Y. Xiang
    • Journal Title

      Chem. Commun.

      Volume: 51 Issue: 5 Pages: 929-932

    • DOI

      10.1039/c4cc06170e

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of LNA nucleobases as an enhancer for the binding of amiloride to an abasic site in DNA/DNA and DNA/RNA duplexes2014

    • Author(s)
      Y. Sato, T. Sato, T. Sato, S. Nishizawa, N. Teramae
    • Journal Title

      Org. Biomol. Chem.

      Volume: 12 Issue: 37 Pages: 7250-7256

    • DOI

      10.1039/c4ob00977k

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Abasic Site-Binding Ligands Conjugated with Cyanine Dyes for "Off-On" Fluorescence Sensing of Orphan Nucleobases in DNA Duplexes and DNA/RNA Hybrids2014

    • Author(s)
      Y. Sato, M. Kudo, Y. Toriyabe, S. Kuchitsu, C.-X. Wang, S. Nishizawa, N. Teramae
    • Journal Title

      Chem. Commun.

      Volume: 50 Issue: 5 Pages: 515-517

    • DOI

      10.1039/c3cc47717g

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Recent Progress in Abasic Site-binding Small Molecules for Detecting Single-base Mutations in DNA2014

    • Author(s)
      S. Nishizawa, Y. Sato, N. Teramae
    • Journal Title

      Analytical Sciences

      Volume: 30 Issue: 1 Pages: 137-142

    • DOI

      10.2116/analsci.30.137

    • NAID

      130004442234

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Trinucleotide duplex formation inside a confined nanospace under supercooled conditions2014

    • Author(s)
      Hiroyuki Arafune, Akira Yamaguchi, Manato Namekawa, Yusuke Sato, Tetsuji Itoh, Ryoko Yoshida, Norio Teramae
    • Journal Title

      Nature Commun.

      Volume: 5 Issue: 1 Pages: 5151-5151

    • DOI

      10.1038/ncomms6151

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Highly sensitive real-time detection of DNA hybridization by using nanoporous waveguide fluorescence spectroscopy2014

    • Author(s)
      Yong Fan, Kazuhiro Hotta, Akira Yamaguchi, Yu Ding, Yonghong He, Norio Teramae, Shuqing Sun, Hui Ma
    • Journal Title

      Appl. Phys. Lett.

      Volume: 105 Issue: 3 Pages: 031103-031103

    • DOI

      10.1063/1.4890984

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 2,4-Diamino-6,7-dimethylpteridine as a Fluorescent Ligand for Binding and Sensing an Orphan Cytosine in RNA Duplexes2013

    • Author(s)
      Y. Sato, Y. Toriyabe, S. Nishizawa, N. Teramae
    • Journal Title

      Chem. Commun.

      Volume: 49 Issue: 85 Pages: 9983-9985

    • DOI

      10.1039/c3cc46085a

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Rational design for cooperative recognition of specific nucleobases using β-cyclodextrin-modified DNAs and fluorescent ligands on DNA and RNA scaffolds2013

    • Author(s)
      A. Futamura, A. Uemura, T. Imoto, Y. Kitamura, H. Matsuura, C. -X. Wang, T. Ichihashi, Y. Sato, N. Teramae, S. Nishizawa, T. Ihara
    • Journal Title

      Chemistry, A European Journal

      Volume: 19 Issue: 32 Pages: 10526-10535

    • DOI

      10.1002/chem.201300985

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inclusion Complexation of γ-Cyclodextrin and Coumarin Dye inside Alumina Nanopores Over a Temperature Range of 303 - 223 K2013

    • Author(s)
      Akira Yamaguchi, Tetsuya Denda
    • Journal Title

      J. Phys. Chem. C

      Volume: 117 Issue: 34 Pages: 17567-17573

    • DOI

      10.1021/jp404504d

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Structural Regulation of Mesoporous Silica and Characterization of the Microenvironment Inside a Silica Mesopore2013

    • Author(s)
      山口央,渋屋祐太,成澤淳,滑川真人,菅原大輝,荒船博之,寺前紀夫
    • Journal Title

      BUNSEKI KAGAKU

      Volume: 62 Issue: 7 Pages: 581-588

    • DOI

      10.2116/bunsekikagaku.62.581

    • NAID

      10031178753

    • ISSN
      0525-1931
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Encapsulation of PEG-modified Myoglobin in Hydrophobic Mesoporous Silica as Studied by Optical Waveguide Spectroscopy2013

    • Author(s)
      H. Arafune, A. Yamaguchi, K. Hotta, N. Teramae
    • Journal Title

      Analytical Sciences

      Volume: 29 Issue: 2 Pages: 187-192

    • DOI

      10.2116/analsci.29.187

    • NAID

      10031156854

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Competitive Binding of Abasic Site-Binding Ligands and Masking Ligands to DNA Duplexes for the Analysis of Single-Base Mutation2013

    • Author(s)
      Y. Sato, T. Kageyama, S. Nishizawa, and N. Teramae
    • Journal Title

      Analytical Sciences

      Volume: 29 Issue: 1 Pages: 15-19

    • DOI

      10.2116/analsci.29.15

    • NAID

      10031147319

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deposition of Polyelectrolyte Multilayer Film on a Nanoporous Alumina Membrane for Stable Label-Free Optical Biosensing2012

    • Author(s)
      K. Hotta, A. Yamaguchi, N. Teramae
    • Journal Title

      J. Phys. Chem. C

      Volume: 116 Issue: 44 Pages: 23533-23539

    • DOI

      10.1021/jp308724m

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microviscosity of Supercooled Water Confined within Aminopropyl-modified Mesoporous Silica as Studied by Time-resolved Fluorescence Spectroscopy2012

    • Author(s)
      A. Yamaguchi, M. Namekawa, T. Itoh, N. Teramae
    • Journal Title

      Analytical Sciences

      Volume: 28 Issue: 11 Pages: 1065-1070

    • DOI

      10.2116/analsci.28.1065

    • NAID

      130004442086

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ratiometric fluorescence signaling of small molecule-environmentally sensitive dye conjugate for detecting single-base mutations in DNA2012

    • Author(s)
      C. Wang, Y. Sato, M. Kudo, S. Nishizawa, and N. Teramae
    • Journal Title

      Chem. Eur. J.

      Volume: 18 Issue: 31 Pages: 9481-9484

    • DOI

      10.1002/chem.201200219

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hierarchically structured periodic mesoporous silica by vapour phase synthesis2012

    • Author(s)
      L. Guo, Y. Fan, H. Arafune, N. Teramae
    • Journal Title

      Micro. Mesopor. Mater.

      Volume: 162 Pages: 122-130

    • DOI

      10.1016/j.micromeso.2012.06.022

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Strong and Selective Binding of Amiloride to an Abasic Site in RNA Duplexes: Thermodynamic Characterization and MicroRNA Detection2012

    • Author(s)
      Y. Sato, T. Ichihashi, S. Nishizawa, and N. Teramae
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 51 Issue: 26 Pages: 6369-6372

    • DOI

      10.1002/anie.201201790

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly selective binding of naphthyridine with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes2012

    • Author(s)
      Y. Sato, Y. Zhang, T. Seino, T. Sugimoto, S. Nishizawa and N. Teramae
    • Journal Title

      Org. Biomol. Chem

      Volume: 10 Issue: 20 Pages: 4003-4006

    • DOI

      10.1039/c2ob25513h

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nanoporous Waveguide Sensor with Optimized Nanoarchitectures for Highly Sensitive Label-Free Biosensing2012

    • Author(s)
      K. Hotta, A. Yamaguchi, N. Teramae
    • Journal Title

      ACS Nano

      Volume: 6 Issue: 2 Pages: 1541-1547

    • DOI

      10.1021/nn204494z

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced fluorescence in a nanoporous waveguide and its quantitative analysis2012

    • Author(s)
      Y. Fan, K. Hotta, A. Yamaguchi, N. Teramae
    • Journal Title

      Opt. Exp

      Volume: 20 Pages: 12850-12859

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Base-Pairing at the AbasicSite in DNA Duplexes and Its Application for Adenosine Aptasensors2012

    • Author(s)
      Y. Pang, Z. Xu, Y. Sato, S. Nishizawa and N. Teramae
    • Journal Title

      ChemBioChem

      Volume: 13 Issue: 3 Pages: 436-442

    • DOI

      10.1002/cbic.201100666

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gapsite-specificformation of fluorescent silver nanoclusters for label-free DNA nucleobase recognition2012

    • Author(s)
      Q. Cui, K. Ma, Y. Shao, S. Xu, F. Wu, G. Liu, N. Teramae, and H. Bao
    • Journal Title

      Anal. Chim. Acta

      Volume: 724 Pages: 86-91

    • DOI

      10.1016/j.aca.2012.02.044

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 多孔性陽極酸化アルミナ膜を用いたナノポーラス光導波路センサー2011

    • Author(s)
      山口央、寺前紀夫
    • Journal Title

      表面技術

      Volume: 62 Pages: 341-345

    • NAID

      10029436393

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Adsorption and Desorption Dynamics of Sodium Dodecyl Sulfate at the Octadecylsilane Layer on the Pore Surface of a Mesoporous Silica Film Observed in-situ by Optical Waveguide Spectroscopy2011

    • Author(s)
      A. Yamaguchi, H. Arafune, K. Hotta, T. Itoh, N. Teramae
    • Journal Title

      Analytical Sciences

      Volume: 27 Issue: 6 Pages: 597

    • DOI

      10.2116/analsci.27.597

    • NAID

      130004827153

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acid-Base Equilibria inside Amine-Functionalized Mesoporous Silica2011

    • Author(s)
      A. Yamaguchi, M. Namekawa, T. Kamijo, T. Itoh, N. Teramae
    • Journal Title

      Anal. Chem.

      Volume: 83 Issue: 8 Pages: 2939-2946

    • DOI

      10.1021/ac102935q

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DNA-Binding Small-Ligand-Immobilized Surface Plasmon Resonance Biosensor for Detecting Thymine-Related Single-Nucleotide Polymorphisms2011

    • Author(s)
      S. Miura, S. Nishizawa, A. Suzuki, Y. Fujimoto, K. Ono, Q. Gao, N. Teramae
    • Journal Title

      Chem. Eur. J.

      Volume: 17 Issue: 50 Pages: 14104-14110

    • DOI

      10.1002/chem.201101290

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Label-free molecular beacon system based on DNAs containing abasic site and fluorescent ligands that bind abasic sites2011

    • Author(s)
      Y. Sato, S. Nishizawa, N. Teramae
    • Journal Title

      Chem. Eur. J.

      Volume: 17 Issue: 41 Pages: 11650-11656

    • DOI

      10.1002/chem.201100384

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence detection of small molecules based on adaptive transitions of abasic site-containing aptamers in combination with abasic site-binding ligands2011

    • Author(s)
      Z. Xu, Y. Sato, S. Nishizawa, and N. Teramae
    • Journal Title

      Biosens. Bioelectron.

      Volume: 26 Issue: 12 Pages: 4733-4738

    • DOI

      10.1016/j.bios.2011.05.051

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescent trimethyl-substituted naphthyridine as a ligand for C-C mismatch detection in CCG trinucleotide repeats2011

    • Author(s)
      Y. Sato, A. Honjo, D. Ishikawa, S. Nishizawa and N. Teramae
    • Journal Title

      Chem. Commun.

      Volume: 47 Issue: 20 Pages: 5885-5887

    • DOI

      10.1039/c1cc11370d

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functionalization of mesoporous silica membrane with a Schiff-base fluorophore for Cu(II) ion sensing2011

    • Author(s)
      X. Chen, N. Teramae, A. Yamaguchi, M. Namekawa, T. Kamijo, A. Tonge
    • Journal Title

      Anal. Chim. Acta

      Volume: 696 Issue: 1-2 Pages: 94-100

    • DOI

      10.1016/j.aca.2011.04.002

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acid-Base Equilibria inside Amine-Functionalized Mesoporous Silica

    • Author(s)
      Akira Yamaguchi, Manato Namekawa, Toshio Kamijo, Tetsuji Itoh, Norio Teramae
    • Journal Title

      Analytical Chemistry

      Volume: (印刷中)(未定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 核酸特定部位に結合する蛍光性分子の開発とその分析化学的応用2014

    • Author(s)
      佐藤雄介
    • Organizer
      日本分析化学会第63年会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2014-09-17
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 蛍光性ペプチド核酸プローブを利用した小分子RNA二重鎖の細胞内動態解析法の開発2014

    • Author(s)
      佐藤貴哉、佐藤 雄介、岩井 健太、久下 周佐、寺前 紀夫、西澤 精一
    • Organizer
      日本分析化学会第63年会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2014-09-17
    • Related Report
      2013 Annual Research Report
  • [Presentation] microRNA を標的とするピラジンーシアニン色素コンジュゲートの開発2014

    • Author(s)
      青木大亮、佐藤 雄介、寺前 紀夫、西澤 精一
    • Organizer
      日本分析化学会第63年会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2014-09-17
    • Related Report
      2013 Annual Research Report
  • [Presentation] ペプチド核酸プローブによる細胞内siRNA解析:リシン残基の導入による機能改良2014

    • Author(s)
      金子充雅、佐藤 雄介、寺前 紀夫、西澤 精一
    • Organizer
      日本分析化学会第63年会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2014-09-17
    • Related Report
      2013 Annual Research Report
  • [Presentation] グアニジノ基を導入したプテリジン誘導体の合成とRNA結合能の評価2014

    • Author(s)
      淺見昂宏、鳥谷部悠、佐藤 雄介、寺前 紀夫、西澤 精一
    • Organizer
      日本分析化学会第63年会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2014-09-17
    • Related Report
      2013 Annual Research Report
  • [Presentation] RNA結合リガンドの合成と分析化学的応用2014

    • Author(s)
      西澤精一
    • Organizer
      第13回化学系若手研究者セミナー
    • Place of Presentation
      東北薬科大学 70周年記念講堂
    • Year and Date
      2014-09-06
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Design and Synthesis of DNA- and RNA-binding Ligands for Analytical Applications2014

    • Author(s)
      Seiichi Nishizawa
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] プテリジン誘導体によるmiRNA検出:置換基改変に基づく結合選択性の制御2014

    • Author(s)
      浅見昂宏、鳥谷部悠、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナフチリジン-シアニンコンジュゲートによるmiRNA蛍光検出2014

    • Author(s)
      岩澤大二郎、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] リシン残基の導入によるペプチド核酸プローブの機能改良と細胞内siRNA解析2014

    • Author(s)
      金子充雅、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] microRNAを標的とするピラジン-シアニン色素コンジュゲートの合成と機能評価2014

    • Author(s)
      青木大亮、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] 蛍光性小分子を用いたmiRNA検出:温度制御による検出感度の向上2014

    • Author(s)
      猪狩佑允、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      みちのく分析科学国際シンポジウム2014
    • Place of Presentation
      東北大学金属材料研究所講堂
    • Year and Date
      2014-08-26
    • Related Report
      2013 Annual Research Report
  • [Presentation] 小さな有機分子による遺伝子分析2014

    • Author(s)
      西澤精一
    • Organizer
      第37回教師のための化学教育講座
    • Place of Presentation
      東北大学理学部化学教室
    • Year and Date
      2014-08-11
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 蛍光性ペプチド核酸プローブを用いた細胞内siRNA解析2014

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      生体機能関連化学部会若手の会 第26回サマースクール
    • Place of Presentation
      ラフォーレ蔵王
    • Year and Date
      2014-07-25
    • Related Report
      2013 Annual Research Report
  • [Presentation] 小分子RNA二重鎖を標的とした蛍光性ペプチド核酸プローブの開発2014

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] 蛍光性小分子を用いたmiRNA検出:温度制御による検出感度の向上2014

    • Author(s)
      猪狩佑允、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナフチリジン-シアニン色素コンジュゲートによるmiRNA蛍光検出2014

    • Author(s)
      岩澤大二郎、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] ピラジン-シアニン色素コンジュゲートの合成とmicroRNAとの相互作用解析2014

    • Author(s)
      青木大亮、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] プテリジン誘導体によるRNA検出:置換基導入による結合選択性の制御2014

    • Author(s)
      浅見昂宏、鳥谷部悠、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] リシン残基の導入によるペプチド核酸プローブの機能改良と細胞内siRNA解析2014

    • Author(s)
      金子充雅、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      東日本分析若手交流会
    • Place of Presentation
      鶴岡メタボロームクラスター レクチャーホール
    • Year and Date
      2014-07-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] siRNA 結合能をもつ蛍光性プローブの開発と細胞内siRNA 解析への応用2014

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      第74回分析化学討論会
    • Place of Presentation
      日本大学工学部
    • Year and Date
      2014-05-24
    • Related Report
      2013 Annual Research Report
  • [Presentation] 蛍光性プテリジン誘導体によるRNA一塩基識別2014

    • Author(s)
      佐藤雄介、鳥谷部悠、寺前紀夫、西澤精一
    • Organizer
      第74回分析化学討論会
    • Place of Presentation
      日本大学工学部
    • Year and Date
      2014-05-24
    • Related Report
      2013 Annual Research Report
  • [Presentation] 小分子RNA機能解析を目指した蛍光性プローブの開発2014

    • Author(s)
      佐藤雄介
    • Organizer
      最先端光計測とライフサイエンスの近未来-バイオ・ラマン2017-
    • Place of Presentation
      東北大学 片平さくらホール
    • Year and Date
      2014-05-01
    • Related Report
      2013 Annual Research Report
  • [Presentation] siRNA 結合能をもつ蛍光性プローブの開発と細胞内デリバリー解析への応用2014

    • Author(s)
      佐藤貴哉
    • Organizer
      最先端光計測とライフサイエンスの近未来-バイオ・ラマン2017-
    • Place of Presentation
      東北大学 片平さくらホール
    • Year and Date
      2014-05-01
    • Related Report
      2013 Annual Research Report
  • [Presentation] ルマジン骨格を有する核酸結合リガンドの合成とmicroRNA検出への応用2014

    • Author(s)
      齊藤裕貴、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス
    • Year and Date
      2014-03-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] アミノ基及びグアニジノ基を導入したプテリジン誘導体の合成とそのRNA脱塩基部位結合能の評価2014

    • Author(s)
      鳥谷部悠、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス
    • Year and Date
      2014-03-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] siRNA選択的蛍光プローブの開発2014

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス
    • Year and Date
      2014-03-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] Chemical Sensing at the Confined Reaction Field2014

    • Author(s)
      Norio Teramae
    • Organizer
      Lecture at ECNU
    • Place of Presentation
      East China Normal University, 上海,中国
    • Year and Date
      2014-03-17
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 核酸結合リガンドの合成と分析化学的応用2014

    • Author(s)
      西澤精一
    • Organizer
      日本化学会東北支部秋田地区講演会
    • Place of Presentation
      秋田大学ベンチャービジネスラボラトリー2F 大セミナー室
    • Year and Date
      2014-02-21
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 細胞内 siRNA 解析を目指した蛍光性プローブの開発2014

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      第7回 6専攻合同シンポジウム 「ヤングブレインズの連携による学際的研究の興隆」
    • Place of Presentation
      東北大学北青葉山キャンパス 理学総合棟
    • Year and Date
      2014-02-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] 規制反応場と分析化学2014

    • Author(s)
      寺前紀夫
    • Organizer
      Lecture at RIKEN
    • Place of Presentation
      理化学研究所, 和光市
    • Year and Date
      2014-02-08
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Design and Synthesis of DNA- and RNA-binding Ligands for Analytical Applications2013

    • Author(s)
      Seiichi Nishizawa
    • Organizer
      The 3rd Dalian University of Technology - Tohoku University Joint Symposium in Chemistry
    • Place of Presentation
      Tohoku Univ. Katahira Sakura-Hall
    • Year and Date
      2013-12-19
    • Related Report
      2013 Annual Research Report
  • [Presentation] 細胞内RNA解析を指向した蛍光性プローブの開発2013

    • Author(s)
      佐藤雄介
    • Organizer
      生物物理学会 東北支部会2013
    • Place of Presentation
      東北大学片平キャンパス生命科学プロジェクト棟1階
    • Year and Date
      2013-12-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] 光導波路分光法によるPEG修飾ミオグロビンの吸着挙動解析2013

    • Author(s)
      山口 央
    • Organizer
      第23回日本MRS年次大会
    • Place of Presentation
      横浜市開港記念会館
    • Year and Date
      2013-12-09
    • Related Report
      2013 Annual Research Report
  • [Presentation] シリカメソ細孔内部におけるポルフィリン誘導体の酸解離反応2013

    • Author(s)
      成澤淳, 渋屋祐太, 山口央
    • Organizer
      第10回茨城地区分析技術交流会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Year and Date
      2013-11-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] アルミナナノ細孔内における短鎖DNA二重鎖形成2013

    • Author(s)
      佐藤翔平, 山口央
    • Organizer
      第10回茨城地区分析技術交流会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Year and Date
      2013-11-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] 円筒状アルミナナノ細孔でのイオン伝導度変化を利用したバイオセンシング法の検討2013

    • Author(s)
      山本良明, 山口央
    • Organizer
      第10回茨城地区分析技術交流会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Year and Date
      2013-11-29
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナノポーラス構造に基づくバイオセンシング2013

    • Author(s)
      山口 央
    • Organizer
      2013年真空・表面科学合同講演会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2013-11-26
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 規制反応場と分析化学2013

    • Author(s)
      寺前紀夫
    • Organizer
      Lecture at Shinshu Univ.
    • Place of Presentation
      信州大学
    • Year and Date
      2013-11-12
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecule Recognition by Fluorophores at the Confined Reaction Fields2013

    • Author(s)
      Norio Teramae
    • Organizer
      15th Beijing Conference and Exhibition on Instrumental Analysis
    • Place of Presentation
      Hotel Nikko New Century Beijing, Beijing, China
    • Year and Date
      2013-10-24
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Design and Synthesis of DNA- and RNA-binding Ligands for Analytical Applications2013

    • Author(s)
      西澤精一
    • Organizer
      平成25年度 化学系学協会東北大会
    • Place of Presentation
      東北大学 川内北キャンパス 川内萩ホール
    • Year and Date
      2013-09-28
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] メソポーラスシリカに吸着した光捕集複合体LH2の立体構造2013

    • Author(s)
      渋屋祐太, 山口央
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学東大阪キャンパス
    • Year and Date
      2013-09-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] ペプチド性側鎖を利用する核酸結合リガンドの開発2013

    • Author(s)
      西澤精一、菅井祥加、佐藤雄介、寺前紀夫
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] 細胞内siRNA解析を指向した蛍光性プローブの開発2013

    • Author(s)
      佐藤雄介、佐藤 貴哉、岩井 健太、久下 周佐、寺前 紀夫、西澤 精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] ペプチド性側鎖の導入によるルマジン誘導体のRNA結合力の向上2013

    • Author(s)
      齊藤裕貴、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] PNA-TO コンジュゲートを用いたsiRNA選択的検出2013

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] microRNA検出を指向した高シトシン選択性プテリジン誘導体の開発2013

    • Author(s)
      鳥谷部悠、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] 小分子リガンドによるmiRNA検出:温度制御による検出感度の改良2013

    • Author(s)
      猪狩佑允、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナフチリジン-シアニン色素コンジュゲートによるmiRNA 蛍光検出2013

    • Author(s)
      岩澤大二郎、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] アルミナナノ細孔内における脱塩基部位含有DNA二重鎖と小分子リガンドの低温錯形成挙動2013

    • Author(s)
      宇田麻希, 樫村成輝, 山口央
    • Organizer
      日本分析化学会第62年会
    • Place of Presentation
      近畿大学東大阪キャンパス
    • Year and Date
      2013-09-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] PNA-TO conjugates as fluorescent probes for siRNA analysis2013

    • Author(s)
      Takaya Sato, Yusuke Sato, Kenta Iwai, Shusuke Kuge, Norio Teramae, Seiichi Nishizawa
    • Organizer
      RSC Tokyo International Conference 2013
    • Place of Presentation
      幕張メッセ 国際展示場
    • Year and Date
      2013-09-06
    • Related Report
      2013 Annual Research Report
  • [Presentation] Low-temperature complexation of a ligand with abasic site-containing DNA inside alumina nanopores2013

    • Author(s)
      Maki Uda, Shigeki Kashimura, Akira Yamaguchi
    • Organizer
      RSC Tokyo International Conference 2013
    • Place of Presentation
      幕張メッセ
    • Year and Date
      2013-09-05 – 2013-09-06
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fabrication of mesoporous silica tubes inside columnar alumina pores2013

    • Author(s)
      Ryotaro Ueno, Kazuyoshi Nasu, Akira Yamaguchi
    • Organizer
      RSC Tokyo International Conference 2013
    • Place of Presentation
      幕張メッセ
    • Year and Date
      2013-09-05 – 2013-09-06
    • Related Report
      2013 Annual Research Report
  • [Presentation] Lumazine-Peptide Conjugates Display Enhanced Affinity for RNA Targets2013

    • Author(s)
      Hiroki Saito, Yusuke Sato, Norio Teramae, Seiichi Nishizawa
    • Organizer
      RSC Tokyo International Conference 2013
    • Place of Presentation
      幕張メッセ 国際展示場
    • Year and Date
      2013-09-05
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fluorescent Pteridine Derivatives for Detecting Cytosine Nucleobase Opposite an Abasic Site in the RNA Duplexes2013

    • Author(s)
      Yu Toriyabe, Yusuke Sato, Norio Teramae, Seiichi Nishizawa
    • Organizer
      RSC Tokyo International Conference 2013
    • Place of Presentation
      幕張メッセ 国際展示場
    • Year and Date
      2013-09-05
    • Related Report
      2013 Annual Research Report
  • [Presentation] Structure of Light-Harvesting Protein LH2 Adsorbed on Mesoporous Silica2013

    • Author(s)
      Yuuta Shibuya, Akira Yamaguchi
    • Organizer
      The Twelfth Asian Conference on Analytical Sciences (ASIANALYSIS XII)
    • Place of Presentation
      Maidashi campus of Kyushu University
    • Year and Date
      2013-08-23
    • Related Report
      2013 Annual Research Report
  • [Presentation] Chemical Sensing at the Confined Reaction Fields2013

    • Author(s)
      Norio Teramae
    • Organizer
      AsianalysisXII
    • Place of Presentation
      Kyushu University, Fukuoka, Japan
    • Year and Date
      2013-08-22
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Effect of Ligand-binding to the Abasic Site on Enzyme Activity2013

    • Author(s)
      Bingyan HAN, Yusuke SATO, Seiichi NISHIZAWA, Norio TERAMAE
    • Organizer
      The Fourteenth International Symposium on Electroanalytical Chemistry (14th ISEAC)
    • Place of Presentation
      中国科学院長春応用化学研究所
    • Year and Date
      2013-08-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] Molecule Recognition by Fluorophores at the Confined Reaction Fields2013

    • Author(s)
      Norio Teramae
    • Organizer
      14th International Symposium on Electroanalytical Chemistry
    • Place of Presentation
      Changchun Institute of Applied Physics, Changchun, China
    • Year and Date
      2013-08-18
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] siRNA 解析を目指したピレン-PNA-TO分子の設計とその機能評価2013

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、寺前紀夫、西澤精一
    • Organizer
      平成25年度日本分析化学会東北支部若手交流会
    • Place of Presentation
      仙台 秋保温泉 岩沼屋
    • Year and Date
      2013-07-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] 温度低下に伴う結合親和力向上を利用した核酸結合性リガンドによるmicroRNA検出2013

    • Author(s)
      猪狩佑允、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      平成25年度日本分析化学会東北支部若手交流会
    • Place of Presentation
      仙台 秋保温泉 岩沼屋
    • Year and Date
      2013-07-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] microRNA検出を指向した ナフチリジン-シアニン コンジュゲートの改良2013

    • Author(s)
      岩澤大二郎、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      平成25年度日本分析化学会東北支部若手交流会
    • Place of Presentation
      仙台 秋保温泉 岩沼屋
    • Year and Date
      2013-07-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] microRNA検出を指向した高シトシン選択性プテリジン誘導体の開発2013

    • Author(s)
      鳥谷部悠、佐藤雄介、寺前紀夫、西澤精一
    • Organizer
      平成25年度日本分析化学会東北支部若手交流会
    • Place of Presentation
      仙台 秋保温泉 岩沼屋
    • Year and Date
      2013-07-19
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fabrication of Hybrid Mesoporous Membrane for Bioanalysis2013

    • Author(s)
      Akira Yamaguchi
    • Organizer
      9th International Workshop on Supramolecular Nanoscience of Chemically Programmed Pigments (SNCOO13)
    • Place of Presentation
      Epoch Ritsumei 21, Biwako-Kusatsu Campus, Ritsumeikan University, Kusatsu, Shiga, Japan
    • Year and Date
      2013-06-29
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] シリカメソ細孔内に閉じ込められた光捕集タンパク質の立体構造評価2013

    • Author(s)
      渋屋祐太, 山口央
    • Organizer
      平成25年度日本分析化学会関東支部若手交流会
    • Place of Presentation
      晴海グランドホテル
    • Year and Date
      2013-06-08
    • Related Report
      2013 Annual Research Report
  • [Presentation] 有機低分子化合物による核酸認識2013

    • Author(s)
      西澤精一
    • Organizer
      第30回 無機分析化学コロキウム
    • Place of Presentation
      東北大学川渡共同セミナーセンター
    • Year and Date
      2013-06-01
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] siRNA 解析を指向したPNA-チアゾールオレンジコンジュゲートの開発2013

    • Author(s)
      佐藤貴哉、佐藤雄介、岩井健太、久下周佐、西澤精一、寺前紀夫
    • Organizer
      第73回 分析化学討論会
    • Place of Presentation
      北海道大学水産学部 函館キャンパス
    • Year and Date
      2013-05-19
    • Related Report
      2013 Annual Research Report
  • [Presentation] アルミナナノ細孔内におけるクマリンーシクロデキストリン包接錯体平衡2013

    • Author(s)
      山口央, 傳田哲矢
    • Organizer
      第73回分析化学討論会
    • Place of Presentation
      北海道大学函館キャンパス
    • Year and Date
      2013-05-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] Molecule Recognition by Fluorescent Ligands using Abasic Site-containing Oligonucleotides2011

    • Author(s)
      Norio Teramae
    • Organizer
      Pittsburg Conference 2011
    • Place of Presentation
      Atlanta, USA(Invited)
    • Year and Date
      2011-03-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性DNA結合小分子を核酸へのラベル化試薬として利用する2011

    • Author(s)
      佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      第13回生命化学研究会シンポジウム(冬季)仙台2011
    • Place of Presentation
      東北大学さくらホール
    • Year and Date
      2011-01-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] TAR RNAを標的とする蛍光性小分子を開発する2011

    • Author(s)
      西澤精一, 珍田裕佳, 佐藤雄介, 寺前紀夫
    • Organizer
      第13回生命化学研究会シンポジウム(冬季)仙台2011
    • Place of Presentation
      東北大学さくらホール
    • Year and Date
      2011-01-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Adsorption and desorption dynamics of mesoporous silica film as studied by optical waveguide spectroscopy2010

    • Author(s)
      H.Arafune, K.Hotta, A.Yamaguchi, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecule Recognition by Fluorescent Ligands Using Abasic Site-Containing Oligonucleotides2010

    • Author(s)
      N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA(Invited)
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Optical Waveguide Sensor Based on Nanoporous/Metal Multilayer Films2010

    • Author(s)
      A.Yamaguchi
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Small molecule-immobilized surface plasmon resonance biosensors for gene detection2010

    • Author(s)
      S.Nishizawa, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Design of label-free molecular beacons based on an abasic site-binding fluorescent molecule2010

    • Author(s)
      Y.Sato, S.Nishizawa, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] A Nanoporous Waveguide Sensor for Highly Sensitive Chemical and Biochemical Detection2010

    • Author(s)
      K.Hotta, A.Yamaguchi, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fluorescent-Signaling Small Ligands for HIV-1 TAR RNA2010

    • Author(s)
      Y.Chinda, Y.Sato, S.Nishizawa, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Template fabrication of nanostructured metal materials with a periodical structure2010

    • Author(s)
      S.Yamaguchi, A.Yamaguchi, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 2-Amino-1,8-naphthyridines as a fluorescent signaling ligand for A-site RNA2010

    • Author(s)
      M.Rokugawa, T.Ichihashi, Y.Sato, S.Nishizawa, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Acid-base equilibria of a series of pH indicator dyes entrapped inside mesoporous silica2010

    • Author(s)
      M.Namekawa, T.Kamijo, A.Yamaguchi, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Highly strong binding of 2-amino-1,8-naphthyidines to an abasic site in RNA duplex and their application to the detection of non-coding microRNA2010

    • Author(s)
      M.Kudo, Y.Sato, S.Nishizawa, N.Teramae
    • Organizer
      The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 核酸/リガンド相互作用解析と分析化学的応用2010

    • Author(s)
      西澤精一
    • Organizer
      GEヘルスケアジャパンセミナーBIA Symposium in仙台
    • Place of Presentation
      東北大学医学部艮陵会館(Invited)
    • Year and Date
      2010-10-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脱塩基部位結合リガンドによる小分子RNA蛍光検出:ナフチリジン誘導体の機能改良2010

    • Author(s)
      工藤恵, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学豊中キャンパス
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性ピラジン誘導体を用いたmicroRNA検出:蛍光特性の改良2010

    • Author(s)
      佐藤雄介, 市橋俊希, 茂木志生乃, 西澤精一, 寺前紀夫
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学豊中キャンパス
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] TAR RNAバルジ構造を標的とする蛍光性小分子の開発2010

    • Author(s)
      珍田裕佳, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学豊中キャンパス
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] rRNAのA-site構造を標的とする蛍光性リガンド設計と相互作用解析2010

    • Author(s)
      六川正文, 市橋俊希, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学豊中キャンパス
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] A Surface Plasmon Resonance Biosensor Based on a Small Ligand for Detecting Orphan Bases in Abasic Site-containing DNA Duplexes2010

    • Author(s)
      S.Nishizawa, N.Teramae
    • Organizer
      2^<nd> Japanese-Russian Young Scientists Conference on Nano-Materials and Nano-Technology
    • Place of Presentation
      Tokyo Institute of Technology, Tokyo, Japan
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Nucleobase Recognition by Fluorescent Ligands based on Abasic Site-containing DNAs2010

    • Author(s)
      N.Teramae
    • Organizer
      Symposium on Molecule Recognition
    • Place of Presentation
      Xi'Nan University,中国(invited)
    • Year and Date
      2010-09-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Nucleobase Recognition by Fluorescent Ligands in Combination with Abasic Site-containing Oligonucleotides2010

    • Author(s)
      N.Teramae
    • Organizer
      Symposium on Analytical Chemistry at Chongqing
    • Place of Presentation
      Chongqing Normal University中国(invited)
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Acid-base equilibria of fluorescent pH indicator adsorbed inside amine-functionalized mesoporous silica2010

    • Author(s)
      M.Namekawa, T.Kamijo, A.Yamaguchi, N.Teramae
    • Organizer
      平成22年度化学系学協会東北大会
    • Place of Presentation
      岩手大学工学部
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of pore diameter for dissociation behavior of pyranine adsorbed iniside mesoporous silica2010

    • Author(s)
      H.Sugawara, M.Namekawa, T.Kamijo, A.Yamaguchi, N.Teramae
    • Organizer
      平成22年度化学系学協会東北大会
    • Place of Presentation
      岩手大学工学部
    • Related Report
      2010 Annual Research Report
  • [Presentation] Study of electrode performance of nanoporous tin oxide film fabricated by anodizatio2010

    • Author(s)
      H.Matsumoto, T.Iimura, A.Yamaguchi, N.Teramae
    • Organizer
      平成22年度化学系学協会東北大会
    • Place of Presentation
      岩手大学工学部
    • Related Report
      2010 Annual Research Report
  • [Presentation] 3,5-diaminopyrazine-immobilized surface plasmon biosensors for detection of nucleic acids2010

    • Author(s)
      C.Wang, Y.Sato, S.Miura, S.Nishizawa, N.Teramae
    • Organizer
      平成22年度化学系学協会東北大会
    • Place of Presentation
      岩手大学工学部
    • Related Report
      2010 Annual Research Report
  • [Presentation] 水素結合性分子と核酸を用いた化学センシング2010

    • Author(s)
      寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス(invited)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性ピラジン誘導体を用いたmicroRNA検出2010

    • Author(s)
      佐藤雄介, 市橋俊希, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性小分子リガンドによるHIV TAR RNAのバルジ構造検出2010

    • Author(s)
      珍田裕佳, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性リガンドによる小分子RNA検出:ナフチリジン誘導体の適用と機能改良2010

    • Author(s)
      工藤恵, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] rRNAのA-site構造を標的とする蛍光性小分子の開発と薬剤スクリーニングへの適用2010

    • Author(s)
      六川正文, 市橋俊希, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] 陽極酸化アルミナ膜の構造制御に基づく高感度ナノポーラス光導波路センサーの開発2010

    • Author(s)
      堀田一海, 山口央, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] アミン修飾メソポーラスシリカ細孔内部におけるプロトン濃度の推定2010

    • Author(s)
      滑川真人, 上條利夫, 山口央, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] 鋳型法による規則性ナノポーラス金属の作製2010

    • Author(s)
      山口進, 山口央, 寺前紀夫
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学川内キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光性小分子を用いた核酸非共有結合ラベル化法の開発2010

    • Author(s)
      佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      東京コンファレンス2010
    • Place of Presentation
      幕張メッセ国際会議場
    • Related Report
      2010 Annual Research Report
  • [Presentation] ナノポーラスアルミナ膜を検出場とした超高感度ラベルフリーバイオセンサーの開発2010

    • Author(s)
      堀田一海, 山口央, 寺前紀夫
    • Organizer
      東京コンファレンス2010
    • Place of Presentation
      幕張メッセ国際会議場
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of a highly sensitive optical biosensor based on a nanoporous alumina membrane2010

    • Author(s)
      K.Hotta, A.Yamaguchi, N.Teramae
    • Organizer
      Tohoku University Global Center of Excellence Program Summer School 2010
    • Place of Presentation
      Tohoku University
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of surface plasmon resonance biosensor based on 3,5-diaminopyrazine derivatives for detection of nucleic acids2010

    • Author(s)
      Chunxia Wang, Yusuke Sato, Sara Miura, Seiichi Nishizawa, Norio Teramae
    • Organizer
      Tohoku University Global Center of Excellence Program Summer School 2010
    • Place of Presentation
      Tohoku University
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脱塩基部位含有RNA二重鎖/蛍光性リガンド相互作用解析と小分子RNA検出2010

    • Author(s)
      工藤恵, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      平成22年度日本分析化学会東北支部「若手交流会」
    • Place of Presentation
      秋田大学ベンチャービジネスラボラトリー
    • Related Report
      2010 Annual Research Report
  • [Presentation] 陽極酸化によるナノポーラス酸化スズ膜電極の開発2010

    • Author(s)
      山口央、飯村輝彦、堀田一海、寺前紀夫
    • Organizer
      第71回分析化学討論会
    • Place of Presentation
      島根大学松江キャンパス
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA-Binding Small Ligand-Immobilized Surface Plasmon Resonance Biosensor for Detecting Single-Nucleotide Polymorphisms

    • Author(s)
      Seiichi NISHIZAWA, Sara MIURA, Akinori SUZUKI, Yukiko FUJIMOTO, Katsuya ONO, Qiang GAO, Norio TERAMAE
    • Organizer
      International Association of Colloid and Interface Scientists, Conference 2012
    • Place of Presentation
      仙台国際センター
    • Related Report
      2012 Annual Research Report
  • [Presentation] RNA を標的とする蛍光性小分子の開発

    • Author(s)
      西澤精一
    • Organizer
      第29回無機分析化学コロキウム
    • Place of Presentation
      東北大学 川渡共同セミナーセンター
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Design of Abasic Site-Specific Small Ligands Conjugated with Cyanine Derivatives for Gene analysis

    • Author(s)
      Yusuke SATO, Seiichi NISHIZAWA, Norio TERAMAE
    • Organizer
      XV International Symposium on Luminescence Spectroscopy
    • Place of Presentation
      Barcelona University, Spain
    • Related Report
      2012 Annual Research Report
  • [Presentation] Selective Binding of Pteridine Derivatives to the Abasic Site in the DNA Duplexes and Their Fluorescence-Based Gene Analysis

    • Author(s)
      Yu TORIYABE, Yusuke SATO, Seiichi NISHIZAWA, Norio TERAMAE
    • Organizer
      XV International Symposium on Luminescence Spectroscopy
    • Place of Presentation
      Barcelona University, Spain
    • Related Report
      2012 Annual Research Report
  • [Presentation] 疎水場感受性プローブを導入したナフチリジン誘導体の合成とRNAとの相互作用解析

    • Author(s)
      齊藤裕貴, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      平成24年度東日本分析若手交流会
    • Place of Presentation
      いこいの村涸沼
    • Related Report
      2012 Annual Research Report
  • [Presentation] 遺伝子解析を指向した脱塩基部位結合蛍光性プテリジン誘導体の開発

    • Author(s)
      鳥谷部悠, 佐藤雄介, Yuanfeng Pang, 西澤精一, 寺前紀夫
    • Organizer
      平成24年度東日本分析若手交流会
    • Place of Presentation
      いこいの村涸沼
    • Related Report
      2012 Annual Research Report
  • [Presentation] 陽極酸化法による多孔質チタニア/チタン積層膜の作製

    • Author(s)
      山本良明, 山口央
    • Organizer
      平成24年度東日本分析若手交流会
    • Place of Presentation
      いこいの村涸沼
    • Related Report
      2012 Annual Research Report
  • [Presentation] 蛍光性リガンドによるRNAの選択的検出

    • Author(s)
      齊藤裕貴, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      みちのく分析科学シンポジウム2012
    • Place of Presentation
      山形大学工学部
    • Related Report
      2012 Annual Research Report
  • [Presentation] 蛍光性リガンドと核酸の相互作用に基づく分析化学

    • Author(s)
      佐藤雄介
    • Organizer
      第14回機能構造と分析化学シンポジウム
    • Place of Presentation
      東北大学理学部化学教室
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Investigation of enzymatic reaction in a nanoporous film by using nanoporous waveguide spectroscopy

    • Author(s)
      Hiroyuki Arafune, Kazuhiro Hotta, Akira Yamaguchi, Tetsuji Itoh and Norio Teramae
    • Organizer
      Tohoku University Campus Asia Summer School 2012
    • Place of Presentation
      Graduate School of Science, Tohoku University
    • Related Report
      2012 Annual Research Report
  • [Presentation] Structure Control of Mesoporous Silica Embedded into Pores of Anodic Alumina Membrane Using a Vapor-phase Synthesis Method

    • Author(s)
      Limin GUO, Hiroyuki ARAFUNE, Manato NAMEKAWA, Yong FAN, and Norio TERAMAE
    • Organizer
      IUMRS-ICA 2012
    • Place of Presentation
      BEXCO, Busan, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脱塩基部位結合リガンド-シアニン色素コンジュゲートによる遺伝子解析

    • Author(s)
      佐藤雄介, 工藤恵, 王春霞, 西澤精一, 寺前紀夫
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道大学高等教育推進機構
    • Related Report
      2012 Annual Research Report
  • [Presentation] 蛍光性小分子と DNA / RNA ハイブリッドとの相互作用解析

    • Author(s)
      齊藤裕貴, 王春霞, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道大学高等教育推進機構
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脱塩基部位結合性プテリジン誘導体を用いたmicroRNA 蛍光検出

    • Author(s)
      鳥谷部悠, 佐藤雄介, Pang Yuanfeng, 西澤精一, 寺前紀夫
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道大学高等教育推進機構
    • Related Report
      2012 Annual Research Report
  • [Presentation] Hybridization of short oligonucleotides in supercooled water confined to silica mesopores

    • Author(s)
      Hiroyuki ARAFUNE, Manato NAMEKAWA, Akira YAMAGUCHI and Norio TERAMAE
    • Organizer
      RSC Tokyo International Conference 2012
    • Place of Presentation
      幕張メッセ国際展示場
    • Related Report
      2012 Annual Research Report
  • [Presentation] Vapor Phase Method to Synthesize Periodic Mesoporous Silica within Anodic Alumina Membrane

    • Author(s)
      Limin GUO, Hiroyuki ARAFUNE, Yong FAN and Norio TERAMAE
    • Organizer
      RSC Tokyo International Conference 2012
    • Place of Presentation
      幕張メッセ国際展示場
    • Related Report
      2012 Annual Research Report
  • [Presentation] RNA結合性小分子を用いた小分子RNA検出

    • Author(s)
      佐藤雄介
    • Organizer
      化学系学協会東北大会
    • Place of Presentation
      秋田大学
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] RNAを標的とする蛍光性小分子リガンド

    • Author(s)
      西澤精一
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] RNA-蛍光性小分子相互作用に基づくmicroRNA 検出

    • Author(s)
      佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脱塩基部位結合能を有する蛍光性プテリジン誘導体を用いたmicroRNA検出

    • Author(s)
      鳥谷部悠, 佐藤雄介, Yuanfeng Pang, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] 蛍光性ルマジン誘導体による小分子RNA検出

    • Author(s)
      齊藤裕貴, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] アルミナ細孔内部におけるクマリン色素とシクロデキストリンの包摂錯体平衡の温度依存性

    • Author(s)
      傳田哲矢, 山口央
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] 陽極酸化法により形成した多孔質チタニア/チタン積層膜の電極特性評価

    • Author(s)
      山本良明, 山口央
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] Abasic site-binding small ligands conjugated with cyanine dyes for gene analysis

    • Author(s)
      Yusuke SATO
    • Organizer
      Sendai Symposium on Analytical Sciences 2012
    • Place of Presentation
      東北大学片平キャンパスWPI棟5階会議室
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Development of lumazine derivatives conjugated with cyanine dyes for microRNA detection

    • Author(s)
      Hiroki SAITO, Yusuke SATO, Seiichi NISHIZAWA and Norio TERAMAE
    • Organizer
      Sendai Symposium on Analytical Sciences 2012
    • Place of Presentation
      東北大学片平キャンパスWPI棟5階会議室
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synthesis and evaluation of pteridine derivatives having alkylamino groups for microRNA analysis

    • Author(s)
      Yu TORIYABE, Yusuke SATO, Yuanfeng PANG, Seiichi NISHIZAWA and Norio TERAMAE
    • Organizer
      Sendai Symposium on Analytical Sciences 2012
    • Place of Presentation
      東北大学片平キャンパスWPI棟5階会議室
    • Related Report
      2012 Annual Research Report
  • [Presentation] Naphthyridine-fluorophore conjugates as ligands for gene analysis

    • Author(s)
      Chun-Xia WANG, Yusuke SATO, Seiichi NISHIZAWA and Norio TERAMAE
    • Organizer
      Sendai Symposium on Analytical Sciences 2012
    • Place of Presentation
      東北大学片平キャンパスWPI棟5階会議室
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of Ratiometric Fluorescent Ligands for Gene Analysis

    • Author(s)
      Yusuke SATO, Chin-Xia Wang, Seiichi Nishizawa and Norio Teramae
    • Organizer
      The Seventh International Forum on Functional Organic Chemistry (IFOC-7)
    • Place of Presentation
      東京大学 弥生講堂 一条ホール
    • Related Report
      2012 Annual Research Report
  • [Presentation] 核酸脱塩基部位に結合する蛍光分子の開発とその応用

    • Author(s)
      寺前紀夫
    • Organizer
      日本バイオマテリアル学会 シンポジウム 2012
    • Place of Presentation
      仙台国際センター
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Fluorescence sensing of nucleic acids based on abasic site-binding small molecules conjugated with cyanine dyes

    • Author(s)
      Yusuke SATO, Megumi KUDO, Yu TORIYABE, Shota KUCHITSU, Chunxia WANG, Seiichi NISHIZAWA, and Norio TERAMAE
    • Organizer
      平成24年度 日本分光学会国際シンポジウム・年次講演会
    • Place of Presentation
      東京工業大学 百年記念館
    • Related Report
      2012 Annual Research Report
  • [Presentation] Analysis of hybridization behavior of short oligonucleotides in supercooled water confined to silica mesopores

    • Author(s)
      Hiroyuki ARAFUNE, Manato NAMEKAWA, Akira YAMAGUCHI, and Norio TERAMAE
    • Organizer
      平成24年度 日本分光学会国際シンポジウム・年次講演会
    • Place of Presentation
      東京工業大学 百年記念館
    • Related Report
      2012 Annual Research Report
  • [Presentation] Binding study of fluorescent pteridine derivatives to abasic site-containing RNA duplexes for microRNA detection

    • Author(s)
      Yu TORIYABE, Yusuke SATO, Yuanfeng PANG, Seiichi NISHIZAWA, and Norio TERAMAE
    • Organizer
      平成24年度 日本分光学会国際シンポジウム・年次講演会
    • Place of Presentation
      東京工業大学 百年記念館
    • Related Report
      2012 Annual Research Report
  • [Presentation] 分析化学の中での教育と研究

    • Author(s)
      寺前紀夫
    • Organizer
      「分離機能とセンシング機能の化学」セミナー2013
    • Place of Presentation
      東北大学片平キャンパス 金属材料研究所
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多孔質ナノ材料の分析化学などへの応用について

    • Author(s)
      山口央
    • Organizer
      富山県衛生研究所合同セミナー
    • Place of Presentation
      富山県衛生研究所
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 温度によるメソポーラスシリカ細孔径の制御

    • Author(s)
      成澤 淳, 渋屋 裕太, 山口 央
    • Organizer
      第23回日本化学会関東支部茨城地区研究交流会
    • Place of Presentation
      日立シビックセンター
    • Related Report
      2012 Annual Research Report
  • [Presentation] シリカメソ細孔内に閉じ込められたタンパク質構造の細孔径と温度依存性

    • Author(s)
      渋屋祐太, 山口央
    • Organizer
      第10回茨城地区分析技術交流会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ空間での短鎖DNA会合挙動の評価

    • Author(s)
      樫村成輝, 山口央
    • Organizer
      第10回茨城地区分析技術交流会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Related Report
      2012 Annual Research Report
  • [Presentation] Biosensing based on interactions between nucleic acids and small ligands

    • Author(s)
      N. Teramae
    • Organizer
      3rd Asian Spectroscopy Conference
    • Place of Presentation
      Xiamen Univ, China
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] Ratiometric fluorescence signaling of naphthyridine-DBD conjugate for the analysis of thymine-related single-base mutation

    • Author(s)
      Y. Sato, C. Wang, S. Nishizawa, and N. Teramae
    • Organizer
      3rd Asian Spectroscopy Conference
    • Place of Presentation
      Xiamen Univ, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fluorescence enhancement by a waveguide mode formed in a nanoporous alumina film

    • Author(s)
      K. Hotta, Y. Fan, A. Yamaguchi, and N. Teramae
    • Organizer
      3rd Asian Spectroscopy Conference
    • Place of Presentation
      Xiamen Univ, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] “Light-up” response to pyrimidine nucleobases opposite an abasic site in DNA duplexes by naphthyridine-cyanine conjugates

    • Author(s)
      M. Kudo, Y. Sato, S. Nishizawa, and N. Teramae
    • Organizer
      3rd Asian Spectroscopy Conference
    • Place of Presentation
      Xiamen Univ, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Strong binding of amiloride to an abasic site in LNA/DNA duplex: Effect of the LNA modification

    • Author(s)
      T. Sato, Y. Sato, S. Nishizawa, and N. Teramae
    • Organizer
      3rd Asian Spectroscopy Conference
    • Place of Presentation
      Xiamen Univ, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Analytical Application of Abasic-site Binding Ligands

    • Author(s)
      N. Teramae
    • Organizer
      14th Beijing Conference and Exhibition on Instrumental Analysis
    • Place of Presentation
      Central Garden Hotel, Beijing, China
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] An Abasic Site in Oligonucleotides as A Platform for Biosensing

    • Author(s)
      N. Teramae
    • Organizer
      13th International Conference on Electroanalytical Chemistry
    • Place of Presentation
      Changchun Institute of Applied Chemistry, Changchun, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecule Recognition based on Abasic Site-binding Fluorescent Ligands

    • Author(s)
      N. Teramae
    • Organizer
      France-Japan Joint Forum, Chemistry of Functional organic Chemistry
    • Place of Presentation
      Strasbourg Univ, France
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 水素結合性分子と核酸を用いた化学センシング

    • Author(s)
      寺前紀夫
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 陽極酸化法によるナノポーラス膜の作製

    • Author(s)
      傳田哲也、山口央
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] フレネル計算によるナノポーラス光導波路センサーの構造最適化

    • Author(s)
      渋屋裕太、山口央
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of anodized nanoporous tin-oxide film electrodes

    • Author(s)
      A. Yamaguchi, T. Iimura, H. Matsumoto, K. Hotta, N. Teramae
    • Organizer
      JAIMA discussion on analytical science and technology 2011
    • Place of Presentation
      Chiba, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Nanofluidic Separation System Based on a Hybrid Mesoporous Membran

    • Author(s)
      A. Yamaguchi, N. Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecule Recognition by Fluorescent Molecules Using Abasic Site-containing DNAs

    • Author(s)
      Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] Abasic Site-Containing Duplex DNA for Analytical Applications

    • Author(s)
      Seiichi Nishizawa, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Sensitive Detection of Adenosine Based on Abasic Site-Containing DNA Duplex and Fluorescent Ligand

    • Author(s)
      Zhiai Xu, Yusuke Sato, Seiichi Nishizawa, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Nanoporous Waveguide Sensor for Highly Sensitive Biosensing

    • Author(s)
      Kazuhiro Hotta, Akira Yamaguchi, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Highly Strong Binding of Small Lignd to an Abasic Site in a RNA Duplex and Its Application to MicroRNA Detection

    • Author(s)
      Yusuke Sato, Seiichi Nishizawa, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effective Proton Concentration Inside Mesoporous Silica Modified with Trimethyl Ammonium Layer

    • Author(s)
      Hiroyuki Arafune, Kazuhiro Hotta, Akira Yamaguchi, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effective Proton Concentration Inside Mesoporous Silica Modified with Trimethyl Ammonium Layer

    • Author(s)
      Manato Namekawa, Toshio Kamijo, Akira Yamaguchi, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Functionalization of Mesoporous Silica Membrane with α-Cyclodextrin and Application for Chiral Separation by Membrane Transportation

    • Author(s)
      Shohei Yoshikawa, Hiroyuki Arafune, Akira Yamaguchi, Norio Teramae
    • Organizer
      IUPAC international congress on analytical sciences 2011 (ICAS2011)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノポーラス光導波路を利用した高感度ラベルフリーバイオセンサー

    • Author(s)
      堀田一海, 山口央,寺前紀夫
    • Organizer
      みちのく分析科学シンポジウム 2011
    • Place of Presentation
      山形大学工学部キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナフチリジン-シアニン誘導体コンジュゲートの合成と遺伝子解析への応用

    • Author(s)
      工藤恵, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      みちのく分析科学シンポジウム 2011
    • Place of Presentation
      山形大学工学部キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] メソポーラスシリカ細孔内部におけるローダミン蛍光寿命の温度依存性

    • Author(s)
      滑川真人, 上條利夫, 山口央, 寺前紀夫
    • Organizer
      みちのく分析科学シンポジウム 2011
    • Place of Presentation
      山形大学工学部キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脱塩基部位を標的とする核酸結合リガンドの開発と遺伝子解析への応用

    • Author(s)
      佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      生体機能関連化学部会若手の会 第23回サマースクール
    • Place of Presentation
      宮島グランドホテル 有もと
    • Related Report
      2011 Annual Research Report
  • [Presentation] 核酸/リガンド相互作用解析と分析化学的応用

    • Author(s)
      西澤精一, 寺前紀夫
    • Organizer
      平成23年度 化学系学協会東北大会
    • Place of Presentation
      東北大学川内北キャンパス
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] RNAバルジ構造を標的とする蛍光性小分子リガンドの開発

    • Author(s)
      西澤精一, 六川正文, 珍田裕桂, 市橋俊希, 佐藤雄介, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脱塩基部位を標的とする核酸結合リガンドの開発と遺伝子解析への応用

    • Author(s)
      佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノポーラス光導波路を利用した高感度ラベルフリーバイオセンサーの開発

    • Author(s)
      堀田一海, 山口央,寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノポーラス光導波路センシング法を利用したシリカメソ細孔への酵素吸脱着挙動の解析

    • Author(s)
      荒船博之, 堀田一海, 山口央, 伊藤徹二, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナフチリジン-シアニン誘導体コンジュゲートを用いた核酸発蛍光検出

    • Author(s)
      工藤恵, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] ジアミノピラジン誘導体とAP site含有LNA/DNA 二重鎖の相互作用解析

    • Author(s)
      佐藤哲史, 佐藤雄介, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] メソポーラスシリカ細孔内における蛍光ダイナミクスの温度依存性

    • Author(s)
      滑川真人, 上條利夫, 山口央,寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] アミン修飾シリカメソ細孔内における酸塩基反応の細孔サイズ依存性

    • Author(s)
      菅原大輝, 滑川真人, 上條利夫, 山口央, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] 蛍光性RNA結合リガンドを利用したmiRNA検出プローブの設計と機能評価

    • Author(s)
      朽津翔太, 珍田裕佳, 伊東良子, 西澤精一, 寺前紀夫
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学東山キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNA-Binding Small Ligand-Immobilized Surface Plasmon Resonance Biosensor Detecting Single-Nucleotide Polymorphisms

    • Author(s)
      Seiichi Nishizawa, Sara Miura, Akinori Suzuki, Katsuya Ono, Qiang Gao, and Norio Teramae
    • Organizer
      第38回国際核酸化学シンポジウム(ISNAC2011)
    • Place of Presentation
      Clark Memorial Student Center, Hokkaido University
    • Related Report
      2011 Annual Research Report
  • [Presentation] A signal-on ATP aptasensor based on nucleobase-specific fluorescent ligands

    • Author(s)
      Zhiai Xu, Yusuke Sato, Seiichi Nishizawa, and Norio Teramae
    • Organizer
      第38回国際核酸化学シンポジウム(ISNAC2011)
    • Place of Presentation
      Clark Memorial Student Center, Hokkaido University
    • Related Report
      2011 Annual Research Report
  • [Presentation] Ratiometric fluorescence detection of thymine-related single-base mutation by naphthyridine-DBD conjugates

    • Author(s)
      Chunxia Wang, Yusuke Sato, Seiichi Nishizawa, and Norio Teramae
    • Organizer
      第38回国際核酸化学シンポジウム(ISNAC2011)
    • Place of Presentation
      Clark Memorial Student Center, Hokkaido University
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fluorescence detection of nucleosides based on abasic site-containing DNA duplex aptamers and small fluorescent ligands

    • Author(s)
      Yuanfeng Pang, Z. Xu, Y. Sato, S. Nishizawa and N. Teramae
    • Organizer
      第38回国際核酸化学シンポジウム(ISNAC2011)
    • Place of Presentation
      Clark Memorial Student Center, Hokkaido University
    • Related Report
      2011 Annual Research Report
  • [Presentation] ハロゲン化に基づくDNA結合リガンドの機能制御

    • Author(s)
      西澤精一
    • Organizer
      2011ハロゲン利用 ミニシンポジウム(第4回臭素化学懇話会年会)
    • Place of Presentation
      宇都宮大学陽東キャンパス3号館3階331教室, 石井会館2階
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 均一メソ多孔体内部の特異環境を利用したバイオセンシング系の構築

    • Author(s)
      山口央
    • Organizer
      第12回機能構造と分析化学シンポジウム
    • Place of Presentation
      東北大学理学部化学教室
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 脱塩基部位結合リガンドを用いた小分子RNA検出

    • Author(s)
      佐藤雄介
    • Organizer
      第12回機能構造と分析化学シンポジウム
    • Place of Presentation
      東北大学理学部化学教室
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 分光学を利用した分析化学の先駆的研究

    • Author(s)
      N. Teramae
    • Organizer
      平成23年度 日本分光学会年次講演会
    • Place of Presentation
      理化学研究所 横浜研究所
    • Related Report
      2011 Annual Research Report
  • [Presentation] 核酸結合リガンドの開発と応用〜DNAからRNA検出へ〜

    • Author(s)
      西澤精一
    • Organizer
      第13回機能構造と分析化学シンポジウム
    • Place of Presentation
      東北大学理学部化学教室
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 物質透過型ナノ多孔膜の開発とバイオ分析への応用

    • Author(s)
      山口央
    • Organizer
      茨城産学連携成果発表会
    • Place of Presentation
      茨城県工学技術センター
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノポーラス光導波路分光法によるナノポーラス膜における固定化酵素の解析

    • Author(s)
      荒船博之、堀田一海、山口央、伊藤徹二、寺前紀夫
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス、矢上キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] マルチカラー蛍光アッセイを指向した脱塩基部位結合リガンド群の開発

    • Author(s)
      佐藤雄介、工藤恵、王春霞、西澤精一、寺前紀夫
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス、矢上キャンパス
    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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