|Budget Amount *help
¥216,970,000 (Direct Cost : ¥166,900,000、Indirect Cost : ¥50,070,000)
Fiscal Year 2014 : ¥18,590,000 (Direct Cost : ¥14,300,000、Indirect Cost : ¥4,290,000)
Fiscal Year 2013 : ¥18,590,000 (Direct Cost : ¥14,300,000、Indirect Cost : ¥4,290,000)
Fiscal Year 2012 : ¥32,110,000 (Direct Cost : ¥24,700,000、Indirect Cost : ¥7,410,000)
Fiscal Year 2011 : ¥72,670,000 (Direct Cost : ¥55,900,000、Indirect Cost : ¥16,770,000)
Fiscal Year 2010 : ¥75,010,000 (Direct Cost : ¥57,700,000、Indirect Cost : ¥17,310,000)
|Outline of Final Research Achievements
It has been expected that the elucidation of the mechanism for the regenerative regulation of intestinal epithelial cells would be applied to the gastrointestinal regenerative medicine.
It has however been technically impossible to assess the normal intestinal epithelial cells ex vivo. In this study, we therefore aimed to assess the function of normal intestinal epithelial cells and to establish the technical basis of clinical application for the primary culture of colonic epithelial cells by developing the long-term, serum-free, 3-dimential culture system of mice normal colon.