| Budget Amount *help |
¥43,550,000 (Direct Cost: ¥33,500,000、Indirect Cost: ¥10,050,000)
Fiscal Year 2012: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2011: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2010: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
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| Research Abstract |
We reported N-ERC/mesothelin might be a useful blood tumor marker for mesothelioma. In order to investigate whether this tumor marker is useful for an early diagnosis in a mass examination, we started a large-scale pilot research screening in Japan for construction workers with the risk of asbestos exposure. In conclusion, it is indicated that the blood tumor marker is useful for an early diagnosis in a mass examination and may lead to the prolongation of their survival. We havedemonstrated that plasma N-ERC levels of rats administered multi-wall carbon nanotube, man-made mineral fibers or chrysotile were continuously higher even at 10 weeks after intraperitoneal (i.p.) injection than the other non-carcinogenic materials.
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