| Budget Amount *help |
¥38,480,000 (Direct Cost: ¥29,600,000、Indirect Cost: ¥8,880,000)
Fiscal Year 2012: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2011: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2010: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
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| Research Abstract |
We have succeeded to develop a technology pipeline to specifically knockdown neuronal cells in any desirable brain regions, which are constructed by integration of the quantitative deepCAGE, the revolutionary technology to identify specific promoters with high accuracy, and the circuit genomics technologies using transgenic mice. Cre transgenic mice, using specific promoters identified by the pipeline, already showed specific recombination in the target regions, indicating usefulness of the mice for the functional analysis of the target brain regions.
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