Biomedical studies of insect models for human diseases to understand their pathogenic mechanism and development of a novel screening method to identify candidates of medicines for human diseases using the insect disease models

• Project/Area Number: 22241052
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Living organism molecular science
• Research Institution: Kyoto Institute of Technology
• Principal Investigator: MORI Hajime 京都工芸繊維大学, 工芸科学研究科, 教授 (80201812)
• Co-Investigator(Kenkyū-buntansha): YAMAGUCHI Masamitsu 京都工芸繊維大学, 工芸科学研究科, 教授 (00182460) ; TAKETANI Shigeru 京都工芸繊維大学, 工芸科学研究科, 教授 (20121949) ; KAMEI Kaeko 京都工芸繊維大学, 工芸科学研究科, 教授 (00214544) ; KOTANI Eiji 京都工芸繊維大学, 工芸科学研究科, 准教授 (10273541) ; YOSHIDA Hideki 京都工芸繊維大学, 工芸科学研究科, 助教 (30570600) ; INOUE Yoshihiro 京都工芸繊維大学, 昆虫バイオメディカル教育研究センター, 准教授 (90201938)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000); Fiscal Year 2012: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000); Fiscal Year 2011: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000); Fiscal Year 2010: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
• Keywords: 昆虫 / 生体機能利用 / 遺伝学 / 蛋白質 / 脳神経疾患 / 昆虫モデル / プロテインチップ / 昆虫ウイルス / ショウジョウバエ / 疾患モデルショウジョウバエ / サイポウイルス / 筋ジストロフィー / メタボリック症候群 / 治療薬スクリーニング

Research Abstract

A neuron-specific depletion of Drosophila orthologue of human responsible gene for ALS resulted in ALS-like phenotypes in Drosophila. It is possible to speculate that ALS may be caused by a reduction of the gene products rather than accumulation of abnormal aggregates. A developmental study of Drosophila diabetes model suggests that activation of the JNK cascade by several types of stress in insulin-producing cells resulted in diabetes-like phenotypes. We constructed polyhedra immobilized BMP-2 growth factor in polyhedral microcrystals from silkworm virus and showed that the implanted polyhedra have activity of bone regeneration on rat calvarial bone.

Research Products

• [Journal Article] Orbit/CLASP is required for germline cyst formation through its developmental control of fusomes and ring canals in Drosophila males (2013)
  • Author(s): Miyauchi, C*, Kitazawa, D*, Ando, I, Hayashi, D. Inoue YH. (* equalcontribute) '
  • Journal Title: PLOS ONE Volume: 8 Issue: 3 Pages: e58220-e58220
  • DOI: 10.1371/journal.pone.0058220
  • Peer Reviewed
• [Journal Article] Expression of freeze responsive proteins F,r10 and Li16, from freeze tolerant frogs enhances freezing survival of BmN insect cells. (2013)
  • Author(s): Kyle K. Biggar; Eiji Kotani; Toshiharu Furusawa Kenneth B. Storey
  • Journal Title: FASEB J. Volume: in press
• [Journal Article] The p53-dependent expression of frataxin controls 5-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photo-damage in cancerous cells. (2013)
  • Author(s): M. Sawamoto, T. Imai, M. Umeda, K. Fukuda, T. Kataoka and S. Taketani
  • Journal Title: Photochem. Photobiol. Volume: 89(1): Issue: 1 Pages: 163-172
  • DOI: 10.1111/j.1751-1097.2012.01215.x
  • Peer Reviewed
• [Journal Article] Erythropoietin is involved in hemoprotein syntheses in developing human decidua. (2013)
  • Author(s): Shiota M, Yasuda Y, Shimaoka M, Tsuritani M, Koike E, Oiki M, Matsubara J, Taketani S, Murakami H, Yamasaki H, Okumoto K, Hoshiai H.
  • Journal Title: Congenit Anom (Kyoto). Volume: 53(1) Issue: 1 Pages: 18-26
  • DOI: 10.1111/j.1741-4520.2012.00382.x
• [Journal Article] Identification of a bacteria-like ferrochelatase gene in Strongyloides venezuelensis, an animal parasitic nematode. (2013)
  • Author(s): Nagayasu E, Ishikawa S, Taketani S, Ooka T, Chakraborty G, Yoshida A, Inagaki Y, Hayashi T, Maruyama H.
  • Journal Title: PLoS One Volume: 8 Issue: 3 Pages: 1-11
  • DOI: 10.1371/journal.pone.0058458
  • Peer Reviewed
• [Journal Article] Congenital Erythropoietic Porphyria: Mutation of the Uroporphyrinogen III Cosynthase Gene in a Vietnamese Patient. (2013)
  • Author(s): D.H.T. Kim, A. Kawazoe, P.D. Bang, N. T. Thanh, S.Taketani
  • Journal Title: Case Rep. Dermatol. Volume: 5, Issue: 1 Pages: 104-109
  • DOI: 10.1159/000350679
  • Peer Reviewed
• [Journal Article] dNF-YB plays dual roles in cell death and cell differentiation during Drosophila eye development. (2013)
  • Author(s): Ly, L.L., Suyari, O., Yoshioka, Y., Tue, N.T., Yoshida, H. and Yamaguchi, M.
  • Journal Title: Gene, Volume: in press,
• [Journal Article] Elimination of Y chromosome-bearing spermatids during spermiogenesis in an autosomal sex-ratio mutant of Drosophila simulans. (2013)
  • Author(s): Yasuno, Y., Inoue, Y. H., Yamamoto, M
  • Journal Title: Gene Genet Syst Volume: in press
• [Journal Article] Bone regeneration by polyhedral microcrystals from silkworm virus. (2012)
  • Author(s): Matsumoto, G., Ueda, T., Shimoyama, J., Ijiri, H., Omi, Y., Yube, H., Sugita, Y., Kubo, K., Maeda, H., Kinoshita, Y., Arias, D. G.G., Shimabukuro, J., Kotani, E., Kawamata, S., and Mori, H.
  • Journal Title: Sci. Rep. Volume: 2巻 Issue: 1 Pages: 935-935
  • DOI: 10.1038/srep00935
  • Peer Reviewed
• [Journal Article] Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma (2012)
  • Author(s): Shimizu T., et al
  • Journal Title: Mol Cancer Res Volume: 10(3) Issue: 3 Pages: 454-468
  • DOI: 10.1158/1541-7786.mcr-11-0347
  • Peer Reviewed
• [Journal Article] XNP/dATRX interacts with DREF in the chromatin to regulate gene expression. (2012)
  • Author(s): Valadez-Graham, V., Yoshioka, Y., Velazquez, O., Kawamori, A. Vazquez.,M., Neumann, A., Yamaguchi, M. and Zurita, M
  • Journal Title: Nucleic Acids Res Volume: 1巻 Issue: 4 Pages: 1460-1474
  • DOI: 10.1093/nar/gkr865
  • Peer Reviewed
• [Journal Article] 、Polycomb repressive complex 2-dependent and ?independent functions of Jarid2 in transcriptional regulation in Drosophila (2012)
  • Author(s): Herz, H.-M., Mohan, M., Garrett, A.-S., Miller, C., Casto, D., Zhang, Y., Seidel, C., Haug, J. S., Florens, L., Washburn, M. P., Yamaguchi, M.Shiekhattar, R. and Shilatifard, A.
  • Journal Title: Mol. Cell. Biol Volume: 132 (9)巻 Issue: 9 Pages: 1683-1693
  • DOI: 10.1128/mcb.06503-11
  • Peer Reviewed
• [Journal Article] MLF is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis (2012)
  • Author(s): Bras, S., Martin-Lanneree, S., Gobert, V., Auge, B., Breig, O., Sanial, M., Yamaguchi, M., Haenlin, M., Plessis, A. and Waltzer, L
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 1109 (13)巻 Issue: 13 Pages: 4986-4991
  • DOI: 10.1073/pnas.1117317109
  • Peer Reviewed
• [Journal Article] Depletion of glutamine enhances sodium butyrate-induced erythroid differentiation of K562 cells.Depletion of glutamine enhances sodium butyrate-induced erythroid differentiation of K562 cells. (2012)
  • Author(s): Hiep,N. C., Kinohira, S., Furuyama, K and Taketani S
  • Journal Title: J. Biochem Volume: 152(6) Issue: 6 Pages: 509-519
  • DOI: 10.1093/jb/mvs097
  • Peer Reviewed
• [Journal Article] COPI-mediated membrane trafficking is required for cytokinesis in Drosophila male meiotic divisions (2012)
  • Author(s): Kitazawa D, Yamaguchi M, Mori. H, Inoue YH
  • Journal Title: J. Cell Sci Volume: 125 Issue: 15 Pages: 3649-60
  • DOI: 10.1242/jcs.103317
  • Peer Reviewed
• [Journal Article] Eudesmane-type sesquiterpene lactones inhibit multiple steps in the NF-κB signaling pathway induced by inflammatory cytokines. (2012)
  • Author(s): Tamura R, Chen Y, Shinozaki M, Arao K, Wang L, Tang W, Hirano S, Ogura H, Mitsui T, Taketani S, Ando M, Kataoka T.
  • Journal Title: Bioorg. Med. Chem. Lett. Volume: 201222(1) Issue: 1 Pages: 207-211
  • DOI: 10.1016/j.bmcl.2011.11.029
  • Peer Reviewed
• [Journal Article] 7. 亜鉛―プロトポルフィリン：安全な食肉色素の開発のための基礎的研究 (2012)
  • Author(s): 竹谷 茂、Chau Tuan Thanh,
  • Journal Title: New Food Industry Volume: 54 (7): Pages: 7-15
• [Journal Article] Transcription factor NF-Y is involved in differentiation of R7 photoreceptor cell in Drosophila (2012)
  • Author(s): Yoshioka, Y., Ly, L. L. and Yamaguchi, M.
  • Journal Title: Biology Open Volume: 1 Issue: 1 Pages: 19-29
  • DOI: 10.1242/bio.2011013
  • Peer Reviewed
• [Journal Article] The warts gene as a novel target of the Drosophila DRE/DREF transcription pathway. (2012)
  • Author(s): Fujiwara, S., Ida, H., Yoshioka, Y., Yoshida, H. and Yamaguchi, M.
  • Journal Title: Am. J. Cancer Res. Volume: 2 (1) Pages: 36-44
• [Journal Article] XNP/dATRX interacts with DREF in the chromatin to regulate gene expression. (2012)
  • Author(s): Valadez-Graham, V., Yoshioka, Y., Velazquez, O., Kawamori, A. Vazquez, M., Neumann, A., Yamaguchi, M. and Zurita, M.
  • Journal Title: Nucleic Acids Res. Volume: 40(4) Pages: 1460-1474
• [Journal Article] Effect of αB-crystallin on protein aggregation in Drosophila (2012)
  • Author(s): Tue, N.T., Shimaji, K., Tanaka, N., Yamaguchi, M.
  • Journal Title: J.Biomed.Biotech. Volume: 2012 Pages: 1-7
  • DOI: 10.1155/2012/252049
  • Peer Reviewed
• [Journal Article] Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. (2012)
  • Author(s): Suyari, O., Kawai, M., Ida, H., Yoshida, H., Sakaguchi, K. and Yamaguchi, M.
  • Journal Title: Gene Volume: 495 (2), Issue: 2 Pages: 104-114
  • DOI: 10.1016/j.gene.2011.12.056
  • Peer Reviewed
• [Journal Article] Drosophila DREF acting via the JNK pathway is required for thorax development (2012)
  • Author(s): Yoshioka, Y., Tue, N.T., Fujiwara, S., Matsuda, R., Valadez-Gtaham, V., Zurita, M., Yamaguchi, M.
  • Journal Title: Genesis Volume: (印刷中) Issue: 8 Pages: 599-611
  • DOI: 10.1002/dvg.22017
  • Peer Reviewed
• [Journal Article] Overexpression of ubiquitin carboxyl terminal hydrolase impairs multiple pathways during eye development in Drosophila melanogaster. (2012)
  • Author(s): Thao, D. T. P, Thuy An, P. N., Yamaguchi, M., Thuoc, T. L.
  • Journal Title: Cell Tissue Res. Volume: 348 (3), Issue: 3 Pages: 453-463
  • DOI: 10.1007/s00441-012-1404-x
  • Peer Reviewed
• [Journal Article] Dynamics of endoreplication during Drosophila posterior scutellar macrochaete development. (2012)
  • Author(s): Kawamori, A., Shimaji, K. and Yamaguchi, M.
  • Journal Title: PLoS ONE Volume: 7(6), Issue: 6 Pages: e38714-e38714
  • DOI: 10.1371/journal.pone.0038714
  • Peer Reviewed
• [Journal Article] Knockdown of the Drosophila Fused in Sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches. (2012)
  • Author(s): Sasayama, H., Shimamura, M., Tokuda, T., Azuma, Y., Yoshida, T., Mizuno, T., Nakagawa, M., Fujikake, N., Nagai, Y. and Yamaguchi, M
  • Journal Title: PLoS ONE Volume: 7(6), Issue: 6 Pages: e39483-e39483
  • DOI: 10.1371/journal.pone.0039483
  • Peer Reviewed
• [Journal Article] Sarcoglycan complex formation is involved in regulation of EGFR signaling during Drosophila eye development. (2012)
  • Author(s): Hashimoto, R., Yoshida, H. and Yamaguchi, M.
  • Journal Title: HOAJ Biology, Volume: 1(1) Issue: 1 Pages: 1-1
  • DOI: 10.7243/2050-0874-1-7
  • Peer Reviewed
• [Journal Article] RNA-based diagnosis in a multicellular specimen by whole mount in situ hybridization using an RNA-specific probe. (2012)
  • Author(s): Ueda T., Kobori, A., Yamayoshi, A., Yoshida, H., Yamaguchi, M. and Murakami, A.
  • Journal Title: Bioorganic & Medicinal Chemistry Volume: 20,
• [Journal Article] DREF is involved in the steroidogenesis via regulation of shadow gene. (2012)
  • Author(s): Park, J.-S., Choi, Y.-J., Thao, D. T. P., Kim, Y.-S., Yamaguchi, M. and Yoo, M.-A.
  • Journal Title: Am. J. Cancer Res. Volume: 2 (6),
• [Journal Article] Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis (2012)
  • Author(s): Ushijima Y, Inoue YH, Konishi T, Kitazawa D, Yoshida H, Shimaji K, Kimura H, Yamaguchi M
  • Journal Title: Chromosome Research Volume: 3 Issue: 3 Pages: 319-31
  • DOI: 10.1007/s10577-012-9276-1
  • Peer Reviewed
• [Journal Article] The warts gene as a novel target of the Drosophila DRE/DREF transcription pathway (2012)
  • Author(s): Fujiwara, S., Ida, H., Yoshioka, Y., Yoshida, H., Yamaguchi, M.
  • Journal Title: Am J.Cancer Res. Volume: 2 Pages: 36-44
  • Peer Reviewed
• [Journal Article] XNP/dATRX interacts with DREF in the chromatin to regulate gene expression (2012)
  • Author(s): Valadez-Graham, V., Yoshioka, Y., Velazquez, O., Kawamori, A.Vazquez, M., Neumann, A., Yamaguchi, M., Zurita, M.
  • Journal Title: Nucleic Acids Res. Volume: 40 Pages: 1460-1474
  • Peer Reviewed
• [Journal Article] Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle (2012)
  • Author(s): Suyari, O., Kawai, M., Ida, H., Yoshida, H., Sakaguchi, K., Yamaguchi, M.
  • Journal Title: Gene Volume: 495 Pages: 104-114
  • Peer Reviewed
• [Journal Article] Polycomb repressive complex 2-dependent and-independent functions of Jarid2 in transcriptional regulation in Drosophila (2012)
  • Author(s): Herz, H.-M., Mohan, M., Garrett, A.-S., Miller, C, Casto, D., Zhang, Y., Seidel, C., Haug, J.S., Florens, L., Washburn, M.P., Yamaguchi, M., Shiekhattar, R., Shilatifard, A.
  • Journal Title: Mol.Cell.Biol. Volume: 32 Pages: 1683-1693
  • Peer Reviewed
• [Journal Article] MLF is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis (2012)
  • Author(s): Bras, S., Martin-Lanneree, S., Gobert, V., Auge, B., Breig, O., Sanial, M., Yamaguchi, M., Haenlin, M., Plessis, A., Waltzer, L.
  • Journal Title: Proc.Natl.Acad.Sci.USA Volume: 109 Pages: 4986-4991
  • Peer Reviewed
• [Journal Article] Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis (2012)
  • Author(s): Ushijima Y., Inoue, Y.H., Konishi, T., Kitazawa, D., Yoshida, H., Shimaji, K., Kimura, H., Yamaguchi, M.
  • Journal Title: Chromosome Res. Volume: 20 Pages: 319-331
  • Peer Reviewed
• [Journal Article] A Drosophila model for the screening of bioavailable NADPH oxidase inhibitors and antioxidants (2011)
  • Author(s): Tu Anh, N. T., Nishitani, M., Harada, S., Yamaguchi, M and Kamei, K
  • Journal Title: Mol. Cell. Biochem Volume: 352(1-2)巻 Issue: 1-2 Pages: 91-8
  • DOI: 10.1007/s11010-011-0743-3
  • Peer Reviewed
• [Journal Article] The use of leukemia inhibitory factor immobilized on virus-derived polyhedra to support the proliferation of mouse embryonic and induced pluripotent stem cells (2011)
  • Author(s): Nishishita, N., Ijiri, H., Takenaka, C., Kobayashi, K., Goto, K., Kotani, E., Itoh, T., Mori, H., Kawamata, S.
  • Journal Title: Biomaterials Volume: 32 Issue: 14 Pages: 3555-3563
  • DOI: 10.1016/j.biomaterials.2010.12.063
  • Peer Reviewed
• [Journal Article] Regulation of intestinal stem cell proliferation by human methyl-CpG-binding protein-2 in Drosopbila (2011)
  • Author(s): Lee,S.-H., Kim, I-J., Kim, J.-G., Kim, Y.-S., Yamaguchi, M., Yoo, M.-A.
  • Journal Title: Cell Struct.Funct. Volume: 36 Pages: 197-208
  • Peer Reviewed
• [Journal Article] Ferrochelatase Catalyzes the Formation of Zn-protoporphyrin of Dry-cured Ham via the Conversion Reaction from Heme in Meat (2011)
  • Author(s): Chau, T.T., Ishigaki, M., Kataoka, T., Taketani, S
  • Journal Title: J.Agric.Food Chem. Volume: 59(22) Pages: 12238-12245
  • Peer Reviewed
• [Journal Article] Roles of porphyrin and iron metabolisms in the δ-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin and photodamage of tumor cells (2011)
  • Author(s): Ohgari Y, Miyata Y, Miyagi T, Gotoh S, Ohta T, Kataoka T, Furuyama K, Taketani S
  • Journal Title: Photochem Photobiol. Volume: 87(5) Pages: 1138-1145
  • Peer Reviewed
• [Journal Article] Cytotrienin A, a translation inhibitor that induces ectodomain shedding of TNF receptor 1 via activation of ERK and p38 MAP kinase (2011)
  • Author(s): Yamada Y, Taketani S, Osada H, Kataoka T
  • Journal Title: Eur J Pharmacol Volume: 667(1-3) Pages: 113-119
  • Peer Reviewed
• [Journal Article] Dynamics of cellular components in meiotic and premeiotic divisions in Drosophila males (2011)
  • Author(s): Inoue, Y.H., Miyauchi, C, Ogata, T., Kitazawa D.
  • Journal Title: InTech Meiosis Volume: 2011 Pages: 66-86
  • Peer Reviewed
• [Journal Article] Essential role of Duox in stabilization of Drosophila wing (2011)
  • Author(s): N.T.T.Anh, M.Nishitani, S.Harada, M.Yamaguchi, K.Kamei
  • Journal Title: J.Biol.l Chem. Volume: Vol.286 Issue: 38 Pages: 33244-33251
  • DOI: 10.1074/jbc.m111.263178
  • Peer Reviewed
• [Journal Article] The use of leukemia inhibitory factor immobilize on virus-derived polyhedra to support the proliferation of mouse embryonic and induced pluripotent stem cells (2011)
  • Author(s): Nishishita, N.Ijiri, H.Takenaka, C.Kobayashi, K.Goto, K Kotani, E.Itoh, T.Mori, H.Kawamata, S.
  • Journal Title: Biomaterials Volume: 32 Pages: 3555-3563
  • Peer Reviewed
• [Journal Article] A Drosophila model for the screening of bioavailable NADPH oxidase inhibitors and antioxidants. (2011)
  • Author(s): Tu Anh, N.T., Nishitani, M., Harada, S., Yamaguchi, M., Kamei, K.
  • Journal Title: Mol.Cell.Biochem. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Analysis of the Eukaryotic Community and Metabolites Found in Clay Wall Material Used in the Construction of Traditional Japanese Buildings. (2011)
  • Author(s): S.Kitajima, K.Kamei, M.Nishitani, H.Sato
  • Journal Title: Biosci., Biotech.Biochem. Volume: 74 Pages: 2083-2086
  • Peer Reviewed
• [Journal Article] Quinolone compounds enhance d-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photosensitivity of tumorcells. (2011)
  • Author(s): Ohgari Y, Miyata Y, Chau, T.T, Kitajima S., Adachi Y, Taketani S
  • Journal Title: J.Biochem. Volume: 149(2) Pages: 153-160
  • Peer Reviewed
• [Journal Article] Egr-1 regulates the transcriptional repression of mouse δ-aminolevulinic acid synthase 1 by heme. (2011)
  • Author(s): Gotoh, S., Nakamura T, Kataoka T., Taketani S.
  • Journal Title: J.Biochem. Volume: 472(1-2) Pages: 28-36
  • Peer Reviewed
• [Journal Article] Syntrophin-2 is required for eye development in Drosophila. Exp (2010)
  • Author(s): Nagai, R., Hashimoto, R., Tanaka, Y., Taguchi, O., Sato, M., Matsukage, A and Yamaguchi, M.
  • Journal Title: Cell. Res Volume: 316 Issue: 2 Pages: 272-285
  • DOI: 10.1016/j.yexcr.2009.10.009
  • Peer Reviewed
• [Journal Article] Syntrophin-2 is required for eye development in Drosophila. (2010)
  • Author(s): Nagai, R., Hashimoto, R., Tanaka, Y., Taguchi, O., Sato, M., Matsukage, A., Yamaguchi, M.
  • Journal Title: Exp.Cell Res. Volume: 316 Pages: 272-285
  • Peer Reviewed
• [Journal Article] Role of DREF in transcriptional regulation of the Drosophila p53 gene. (2010)
  • Author(s): Tue, N.T., Thao, D.T.P., Yamaguchi, M.
  • Journal Title: Oncogene Volume: 29 Pages: 2060-2069
  • Peer Reviewed
• [Journal Article] Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype. (2010)
  • Author(s): Umehara, M., Ichikawa, A., Sakamoto, H., Yamada, A., Yoshioka, Y., Yamaguchi, M., Ikura, K.
  • Journal Title: Mol.Cell.Biochem Volume: 342 Pages: 223-232
  • Peer Reviewed
• [Journal Article] Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology. (2010)
  • Author(s): Nagai, R., Hashimoto, R., Yamaguchi, M.
  • Journal Title: Exp.Cell Res Volume: 316 Pages: 2313-2321
  • Peer Reviewed
• [Journal Article] Overexpression of transglutaminase in the Drosophila wing disc induced an extra wing crossve in phenotype. (2010)
  • Author(s): Ichikawa, A., Yamada, A., Sakamoto, H., Umehara, M., Yoshioka, Y., Yamaguchi, M., Ikura, K.
  • Journal Title: Biosci.Biotechnol.Biochem. Volume: 74 Pages: 2494-2496
  • Peer Reviewed
• [Journal Article] NF-Y transcriptionally regulates the Drosophila p53 gene. (2010)
  • Author(s): Tue, N.T., Yoshioka, Y., Yamaguchi, M.
  • Journal Title: Gene Volume: 473 Pages: 1-7
  • Peer Reviewed
• [Journal Article] dGirdin a new player of Akt/PKB signaling in Drosophila melan ogaster. (2010)
  • Author(s): Yamaguchi, M., Suyari, O., Nagai, R., Takahashi, M.
  • Journal Title: Front.Biosci. Volume: 15 Pages: 1164-1171
  • Peer Reviewed
• [Journal Article] Neutralization of Toxic Heme by Porphyromonas gingivalis Hemoglobin Receptor. (2010)
  • Author(s): N.T.Nhien, N.T.Huy, M.Naito, T.Oida, D.T.Uyen, M.Huang, M.Kikuchi, S.Harada, K.Nakayama, K.Hirayama, K.Kamei.
  • Journal Title: J Biochem. Volume: 147(3) Pages: 317-325
  • Peer Reviewed
• [Journal Article] Structural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia. (2010)
  • Author(s): H.Kojima, J.Akaki, S.Nakajima, K.Kamei, M.Tamesada
  • Journal Title: J Nat Med Volume: 64 Pages: 16-23
  • Peer Reviewed
• [Journal Article] Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity. (2010)
  • Author(s): Kitajima S, Kamei K, Taketani S, Yamaguchi M, Kawai F, Komatsu A, Inukai Y.
  • Journal Title: BMC Biochem. Volume: 11 Pages: 6-6
  • Peer Reviewed
• [Journal Article] The Relationship between Iron-Removal Reaction and the Conversion of Heme to Zn-Protoporphyrin. (2010)
  • Author(s): Chau TT, Ishigaki M, Kataoka T, Taketani S.
  • Journal Title: Biosci Biotechnol Biochem. Volume: 74(7) Pages: 1415-1420
  • Peer Reviewed
• [Journal Article] The low expression allele (IVS3-48C) of the ferrochelatase gene 1 eads to the low enzyme activityassociated with erythropietic protoporphyria. (2010)
  • Author(s): Tahara, T., Yamamoto, M., Akagi, R., Harigae, H., Taketani, S.
  • Journal Title: Int.J.Hematol. Volume: 92 Pages: 769-771
  • Peer Reviewed
• [Journal Article] Overexpression of ubiquitin carboxyl terminal hydrolase impairs multiple pathways during eye development in Drosophila melanogaster
  • Author(s): Thao, D.T.P, Thuy An, P.N., Yamaguchi, M., Thuoc, T.L.
  • Journal Title: Cell and Tissue Research Volume: (In press)
  • Peer Reviewed
• [Journal Article] COPI-mediated membrane trafficking is required for cytokinesis in Drosophila male meiotic divisions
  • Author(s): Kitazawa, D., Yamaguchi, M., Mori, H.Inoue, Y.H.
  • Journal Title: J.Cell Science Volume: (In press)
  • Peer Reviewed
• [Presentation] 癌特異的ALA誘導性Protoporphyrinの蓄積：酵素、遺伝子発現および物質輸送からの検討 (2013)
  • Author(s): 竹谷 茂
  • Organizer: 日本農芸化学会大会
  • Place of Presentation: 仙台市
• [Presentation] カイコ後部絹糸腺における細胞増殖因子固定化多角体の発現 (2012)
  • Author(s): 山本尚人・小谷英治・山本賢二・内野恵郎・瀬筒秀 樹・田村俊樹・森 肇
  • Organizer: 大会-昆虫機能・利用学 術講演会
  • Place of Presentation: 上田市
• [Presentation] カイコTIA-1ホモローグとバキュロウイルス核酸結合タンパク質との相互作用に関する研究 (2012)
  • Author(s): 小谷英治・武藤清佳・森 肇
  • Organizer: 平成24年度日本蚕糸学会合同支部大会-昆虫機能・利用学 術講演会
  • Place of Presentation: 上田市
• [Presentation] 鉄シャペロンfrataxin発現のp53による調節とミトコンドリアのヘム代謝の関係 (2012)
  • Author(s): 竹谷 茂
  • Organizer: 第85回日本生化学会
  • Place of Presentation: 福岡市
• [Presentation] Cabezaノックダウンはショウジョウバエ成虫複眼の形態異常を誘導する (2012)
  • Author(s): 島村 真衣、東 裕美子、笹山 博司、徳田 隆 彦、中川 正法、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Polo and KLP3A-Feo complex are required for accumulation of Orbit/CLASP on contractile ring in Drosophila male meiosis. (2012)
  • Author(s): Kitazawa, D., Miyauchi, C. and Inoue, Y. H.
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ノロウイルスとポリオウイルス擬似粒子の多角体への固定化と応用 (2012)
  • Author(s): 西村賢・小谷英治・森肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] Bacillus thuringiensisδ内毒素の多角体への固定化とその応用 (2012)
  • Author(s): 原田佳寛・小谷英治・浅野眞一郎・森 肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] カイコ後部絹糸腺における細胞増殖因子固定化多角体の発現 (2012)
  • Author(s): 山本尚人・小谷英治・山本賢二・内野恵郎・瀬筒秀樹・田村俊樹・森 肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] 変異型カイコサイポウイルス多角体の作製とその利用 (2012)
  • Author(s): 新谷英也・小谷英治・森 肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] バキュロウイルスベクターを用いたモンシロチョウ由来ピエリシンの発現 (2012)
  • Author(s): 喜多友祐・小谷英治・山本真史・森 肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] カイコTIA-1ホモローグとバキュロウイルス核酸結合タンパク質との相互作用に関する研究 (2012)
  • Author(s): 小谷英治・武藤清佳・森 肇
  • Organizer: 平成２４年度日本蚕糸学会合同支部大会―昆虫機能・利用学術講演会
  • Place of Presentation: 上田市
• [Presentation] 鉄シャペロンfrataxin発現のp53による調節とミトコンドリアのヘム代謝の関係 (2012)
  • Author(s): 竹谷 茂
  • Organizer: 第８５回日本生化学会
  • Place of Presentation: 福岡市
• [Presentation] ヒト白血病細胞K562のグルタミン欠乏による赤血球分化 (2012)
  • Author(s): 川添麻子、Nguyen Canh Hiep、木平成子、古山和道、竹谷 茂
  • Organizer: 第８５回日本生化学会
  • Place of Presentation: 福岡市
• [Presentation] ABCG2 の発現とポルフィリン輸送の関係 (2012)
  • Author(s): 牟安峰、川添麻子、植田 亮、岩井一宏、竹谷 茂
  • Organizer: 第８５回日本生化学会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエDNAポリメラーゼ p255サブユニットと相互作用する遺伝子の探索 (2012)
  • Author(s): 前田 頌太、須鑓 理、佐橋 律子、稲葉 泰裕、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエ DOCK family遺伝子の機能解析 (2012)
  • Author(s): 森下 和茂、小笹 史登、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエMcm10と遺伝的相互作用する因子の網羅的探索 (2012)
  • Author(s): 多賀 文乃、稲葉 泰裕、須鎗 理、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] A Drosophila Model for Function Analysis of Organic Carrier Partner 1 (2012)
  • Author(s): Nguyen Huu Tho, Masamitsu Yamaguchi, Hideki Yoshida, Seiji Miyata
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエ精子形成過程におけるエビジェネティック制御因子 (2012)
  • Author(s): 戸田 成美、笹井 信広、吉田 英樹、井上 喜博、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエ転写因子DREFを中心とした転写制御ネットワーク : DREFの標的としてのHippo経路関連遺伝子の同定 (2012)
  • Author(s): 藤原 俊介、堀井 健志、平塚 賢、大川 恭行、須山 幹太、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] dNF-YB Plays Dual Roles in Cell Death and Cell Differentiation of Drosophila Eye Developmental (2012)
  • Author(s): Ly Luong Linh, Tue Nguyen Trong, Osamu Suyari, Yasuhide Yoshioka, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] ショウジョウバエDNAポリメラーゼとヒストンメチル化酵素Pr-Set7の遺伝学的相互作用 (2012)
  • Author(s): 佐橋 律子、須鎗 理、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] mRNA新規小胞体標的化機構の分子メカニズムの解明 (2012)
  • Author(s): 梅河内隆成、臼井一馬、佐藤哲也、須山幹太、大川恭行、山口政光、吉田英樹
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] 蛍光タンパク質を基盤とした小胞他標的化RNA可視化システムの構築 (2012)
  • Author(s): 越田大夢、山田百子、梅河内隆成、Krause Henry、山口政光、吉田英樹
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] The length of male meiotic spindle is determined by the Cell volume of mature primary spermatocytes in Drosophila species. (2012)
  • Author(s): Kitazawa, D., Ogata, T. and Inoue, Y. H.
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Insulin and TOR signaling pathways induce cell growth in Drosophila spermatocyte. (2012)
  • Author(s): Ogata, T., Matsuo, T. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Nuclear envelope proteins, LaminDm0 and Nup107-160 complex influences cytokinesis in Drosophila male meiosis. (2012)
  • Author(s): Hayashi, D., Kitazawa, D. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Proper dynamics of mitochondria is required for male meiosis and formation of mitochondrial aggregates in Drosophila spermatogenesis. (2012)
  • Author(s): Matsuo, T., Oka, S., Ogata, T. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Activation of Sirtuin and induction of the stress responsive genes in Drosophila (2012)
  • Author(s): Nakahara, Y., Oka, S., Ogata, T. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Orbit, a Drosophila ortholog of CLASP plays a role as a centriole elongation factor in primary spermatocytes. (2012)
  • Author(s): Asano, Y., Ando, I,, Kitazawa, D. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] A role of LARP7 protein in Drosophila hematopoiesis in larval lymph gland (2012)
  • Author(s): Ozeki, T. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Accumulation of Reactive Oxygen Species in nervous system or musculature accelerates aging of Drosophila adult (2012)
  • Author(s): Oka, S., Yasukawa, T. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] The RNA-binding protein LARP7 is localized on histone locus and is essential for its expression in Drosophila spermatocytes. (2012)
  • Author(s): Awane, R. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Knockdown of COPII components causes the failure of cytokinesis in Drosophila male meiotic division. (2012)
  • Author(s): Kaizuka, K., Kitazawa, D. and Inoue, Y. H.
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 福岡市
• [Presentation] Orbit, a Drosophila ortholog of CLASP is required for centriole elongation in primary spermatocytes before meiotic division. (2012)
  • Author(s): Asano, Y., Ando, I., Kitazawa, D. and Inoue, Y. H.
  • Organizer: 第64回日本細胞生物学会
  • Place of Presentation: 神戸市
• [Presentation] DJ-1 and mitochondrial fusion/fission factors are required for formation of a large mitochondrial derivative in Drosophila spermatids. (2012)
  • Author(s): Matsuo, T., Oka, S., Ogata, T. and Inoue, Y. H.
  • Organizer: 第64回日本細胞生物学会
  • Place of Presentation: 神戸市
• [Presentation] Involvement of dMLF in JNK signaling pathway (2011)
  • Author(s): Yanai, H., Nakao, Y., Yoshioka, Y., Yoshida, H., Yamaguchi, M.
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] キイロショウジョウバエDOCK family CG31048遺伝子のR7光受容細胞分化への関与 (2011)
  • Author(s): 江口晃一、吉岡泰秀、吉田英樹、宮田清司、日合弘、山口政光
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] ショウジョウバエヒストンメチル化酵素dG9aの機能解析 (2011)
  • Author(s): 小西貴大、嶋路耕平、吉田英樹、山口政光
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] ショウジョウバエの初期発生におけるdG9aの機能及びヒストン修飾の解析 (2011)
  • Author(s): 田中伸太朗、小西貴大、牛島悠太、木村宏、吉田英樹、山口政光
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] Screen of genetic interactants of Drosophila histone H3 lysine 9 methyltransferase G9a (2011)
  • Author(s): 嶋路耕平、小西貴大、牛島悠太、吉田英樹、山口政光
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] Drosophila NF-YB plays multiple roles (2011)
  • Author(s): Ly Luong Linh, Tue Nguyen Trong, Osamu Suyari, Yasuhide Yoshioka, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-16
• [Presentation] Functional analysis of dMCM10 and genetic interaction with dRECQ4 (2011)
  • Author(s): Ayano Taga, Yasuhiro Inaba, Osamu Suyari, Lynn Gringard, Sue Cotterill, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-15
• [Presentation] ヒト白血病細胞株におけるカスパーゼ8の細胞内局在 (2011)
  • Author(s): 木村奏恵、片岡孝夫、竹谷茂
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-15
• [Presentation] カイコTIA-1ホモローグタンパク質とバキュロウイルス核酸結合タンパク質との相互作用の解析 (2011)
  • Author(s): 小谷英治、福嶋真実、森肇
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-15
• [Presentation] Essential role of Duox in the stabilization of Drosophila wing (2011)
  • Author(s): Tu Anh Nguyen Thi, Maiko Nishitani, Masamitsu Ymaguchi, Kaeko Kamei
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] Temporal and special expression pattern of DREF during Drosophila macrocheate development (2011)
  • Author(s): Akihito Kawamori, Masamitsu Yamaguchi
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] Visualization of ER targeted RNA in Drosophila S2 cells (2011)
  • Author(s): Hideki Yoshida, Hiromu Kochida, Takanari Umegawachi, Momoko Yamada, Henri Krause, Masamitsu Yamaguchi
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] カスパーゼ8制御因子c-FLIP1はFasリガンドによるNF-kBの活性化を正負に調節する (2011)
  • Author(s): 松下由果、松尾健太郎、竹谷茂、片岡孝夫
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] 転写因子発現による核内ヘム局在性のイメージング (2011)
  • Author(s): 伊藤隆平、藤田賢一、福田康二、片岡孝夫、佐上郁子、竹谷茂
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] 核因子によるアミノレブリン酸合成酵素1発現の調節機構 (2011)
  • Author(s): 梅田茉奈、後藤紗季、片岡孝夫、竹谷茂
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] ショウジョウバエのインスリンならびにTORシグナル伝達系は精母細胞の細胞成長の誘導に必要である (2011)
  • Author(s): 緒方翼, 上石暁, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] Orbit/CLASP plays a role as linker connecting between Microtubules and Actin filament on contractile ring in Drosophila male meiosis (2011)
  • Author(s): 北澤大志, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] Orbit/CLASPはショウジョウバエ雄減数分裂において中心小体の伸長制御に関与する (2011)
  • Author(s): 浅野裕貴, 安藤至, 北澤大志, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] 酸化ストレスがショウジョウバエ精巣内細胞のミトコンドリアに及ぼす影響についての発生遺伝学的解析 (2011)
  • Author(s): 松尾樹, 岡沙織, 緒方翼, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] Knockdown of nuclear lamins and nucleoporins causes cell division defects in Drosophila male meiosis (2011)
  • Author(s): 林大輔, 北澤大志, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] ショウジョウバエ成虫の脳神経系及び筋肉細胞への活性酸素種の蓄積とそれによる生体老化の促進 (2011)
  • Author(s): 岡沙織, 安川隆司, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] LAEP7タンパク質によるショウジョウバエ血球細胞の増殖と分化の制御 (2011)
  • Author(s): 尾関智彦, 井上喜博
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜市・パシフィコ横浜
  • Year and Date: 2011-12-13
• [Presentation] 癌細胞におけるミトコンドリアの鉄代謝の機能低下とALA-PDT (2011)
  • Author(s): 竹谷茂
  • Organizer: 日本生化学会
  • Place of Presentation: 京都市・京都国際会議場(招待講演)
  • Year and Date: 2011-09-23
• [Presentation] Genetic interaction between LARP family proteins and multiple roles of LARP1 in meiotic divisions in Drosophila males. (2010)
  • Author(s): Inoue, Y.H., Ichihara, K.
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] Dynamic localization of the Orbit/CLASP during meiotic divisionsin Drosophila males and elucidation of its regulatory mechanism. (2010)
  • Author(s): Miyauchi, C., Ando, L, Kitazawa, D., Inoue, Y.H.
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] ショウジョウバエ成虫体内における活性酸素の蓄積とそれによる生体老化の促進 (2010)
  • Author(s): 安川宏司、岡沙織、井上喜博
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] インスリンならびにTORシグナル伝達系によるショウジョウバエ精母細胞の細胞成長の誘導 (2010)
  • Author(s): 緒方翼、上石暁、井上喜博
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] ショウジョウバエ雄の減数分裂における核ラミンおよび核膜孔タンパクimportin-bおよびNupsの変化 (2010)
  • Author(s): 林大輔、北澤大志、井上喜博
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] Orbit/CLASP, a possible direct linker between central spindle and contractile ring in Drosophila male meiosis. (2010)
  • Author(s): Kitazawa, D., Miyauchi, C., Inoue, Y.H
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] Mapping of functional domains in the Orbit protein required for cellular localization in Drosophila male meiosis (2010)
  • Author(s): Miyauchi, C., Kitazawa, D., Inoue, Y.H.
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-12
• [Presentation] DREF is critical for thorax development at least by regulating pcna gene transcription in shaft cells in Drosophila (2010)
  • Author(s): Akihito Kawamori, Masamitsu Yamaguchi
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] ショウジョウバエDNAポリメラーゼaとヒストンメチル化酵素Pr-Set7の遺伝学的相互作用 (2010)
  • Author(s): 佐橋律子、須鎗理、駒井俊亮、前田頌太、吉田英樹、Sue Cotterill、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] ショウジョウバエ複製関連タンパク質Mcm10のゲノム安定性への関与 (2010)
  • Author(s): 稲葉泰裕、須鎗理、福井翔悟、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] ショウジョウバエ転写因子dNF-Yのhedgehogシグナル伝達経路への関与 (2010)
  • Author(s): 平薮哲平、吉岡泰秀、吉田英樹、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] DRE/DREFシステムの新たな標的としてのHippo経路の同定 (2010)
  • Author(s): 藤原俊介、井田寛之、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] ショウジョウバエの胚発生におけるG9aの機能及びヒストン修飾の解析 (2010)
  • Author(s): 小西貴大、田中伸太朗、牛島悠太、加藤容子、木村宏、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] ショウジョウバエの精子形成過程におけるG9aの機能及びヒストン修飾の解析 (2010)
  • Author(s): 牛島悠太、北澤大志、井上喜博、木村宏、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] 遺伝性神経変性疾患ALS(筋萎縮性側索硬化症)モデルショウジョウバエを用いた病態解析 (2010)
  • Author(s): 笹山博司、島村真依、徳田隆彦、山口政光、中川正法
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] Analyses of in vivo role of Drosophila NF-YB by overexpression and knockdown (2010)
  • Author(s): Ly Luong Linh, Tue Nguyen Trong, Osamu Suyari, Yasuhide Yoshioka, Masamitsu Yamaguchi
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] NF-Y transcriptionally regulates the Drosophila p53 gene (2010)
  • Author(s): Tue Nguyen Trong, Yasuhide Yoshioka, Masamitsu Yamaguchi
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] キイロショウジョウバエDock family CG31048遺伝子のR7光受容細胞分化への関与 (2010)
  • Author(s): 江口晃一、吉岡泰秀、吉田英樹、宮田清司、日合弘、山口政光
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-11
• [Presentation] がん細胞特異的ALA-誘導性PDTと鉄利用に関する研究 (2010)
  • Author(s): 宮田善信、大狩佳子、片岡孝夫、竹谷茂
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同年会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-10
• [Presentation] p22-heme binding proteinと相互作用する蛋白質分子の単離と機能解析 (2010)
  • Author(s): 福田康二、河野祐輔、片岡孝夫、岩井一宏、竹谷茂
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同年会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-10
• [Presentation] Quinolone compounds enhance delta-amino levulinic acid (ALA)-induced accumulation of protoporphyrin and photosensitivity of tumor cells (2010)
  • Author(s): 大狩佳子、宮田善信, Tuan Thanh Chau, 北島佐紀人、足立靖、竹谷茂
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同年会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-10
• [Presentation] ウイルス感染に伴うカイコTIA-1相同性タンパク質の細胞内分布変化の解析 (2010)
  • Author(s): 小谷英治・武藤清佳・福嶋真実・森肇
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
  • Place of Presentation: 神戸国際会議場、兵庫県神戸市
  • Year and Date: 2010-12-09
• [Presentation] ポルフィリン症と鉄代謝 (2010)
  • Author(s): 竹谷茂
  • Organizer: 第34回日本鉄バイオサイエンス学会
  • Place of Presentation: 東京国際フォーラム、東京(招待講演)
  • Year and Date: 2010-09-11
• [Presentation] A loss of LARP1 results in multiple phenotypes of spermatogenesis in Drosophila. 1^<st> Ann Meeting of the LARP society. (2010)
  • Author(s): Ichihara, K., Shimizu, H., Inoue, Y.H.
  • Organizer: 1^<st> International meeting of the LARP Society
  • Place of Presentation: Imperial College, UK
  • Year and Date: 2010-09-02
• [Presentation] Role of DNA replication related factor(DREF)in Drosophila melanogastor bristles developmentキイロショウジョウバエの機械感覚毛の形成におけるdrefの役割について (2010)
  • Author(s): Akihito Kawamori, Masamitsu Yamaguchi
  • Organizer: 第43回日本発生生物学会年会
  • Place of Presentation: 京都市・国立京都国際会館
  • Year and Date: 2010-06-20
• [Presentation] The COPI complex is required for spindle formation and cytokinesis during meiotic cell division in Drosophila. (2010)
  • Author(s): Kitazawa, D., Inoue, Y.H
  • Organizer: 第43回日本発生生物学会年会
  • Place of Presentation: 京都市・国立京都国際会館
  • Year and Date: 2010-06-20
• [Presentation] The COPI complex is required for spindle formation and cytokinesis during meiotic cell division in Drosophila. (2010)
  • Author(s): Kitazawa, D., Inoue, Y.H.
  • Organizer: 第62回日本細胞生物学会大会
  • Place of Presentation: 大阪国際会議場,大阪市
  • Year and Date: 2010-05-19
• [Presentation] バキュロウイルス感染によるカイコRNA結合タンパク質(BmTRN-1)の局在変化 (2010)
  • Author(s): 武藤清佳・松本恵実・田辺徹・中村仁・山本賢二・森肇・小谷英治
  • Organizer: 平成22年度蚕糸・昆虫機能利用学術講演会.日本蚕糸学会第80回記念大会
  • Place of Presentation: 信州大学、上田市
  • Year and Date: 2010-04-03
• [Presentation] Mutations of cypovirus polyhedrin and applications of polyhedra to protein nanocontainers (2010)
  • Author(s): Y.Ohtsuka, D.Nakai, F.Coulibaly, E.Chiu, P.Metcalf, H.Mori
  • Organizer: Nanotech Conference & Expo 2010
  • Place of Presentation: Anaheim, CA, USA
• [Presentation] Dynamic changes of dG9a distribution and histone H3K9 methylation pattern during Drosophila spermatogenesis. (2010)
  • Author(s): Ushijima, Y., Konishi, T., Tanaka, S., Kitazawa, D., Kimura, H., Inoue, Y.H., Yamaguchi, M.
  • Organizer: International symposium on "Epigenome network, development and reprogramming of germcells"
  • Place of Presentation: Centinental Hall, Fukuoka, Japan
• [Presentation] Novel RNA binding protein families, LARPs are required for male meiotic divisions in Drosophila and show an interaction with Polycomb group proteins. (2010)
  • Author(s): Yoshihiro H.Inoue, Keiko Ichihara, Daishi Kitazawa, Masamitsu Yamaguchi
  • Organizer: International symposium on "Epigenome network, development and reprogramming of germcells"
  • Place of Presentation: Centinental Hall, Fukuoka, Japan
• [Presentation] 増殖因子を固定したカイコサイポウイルス多角体による各種細胞の培養 (2010)
  • Author(s): 井尻宏志・西村彦人・山岡綾子
  • Organizer: 日本蚕糸学会第80回大会
  • Place of Presentation: 信州大学、上田市
• [Presentation] EGF,NGFおよびFGF-7固定化T赤く体によるウサギ角膜上皮細胞の培養 (2010)
  • Author(s): 杉本容子・井尻宏志・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] カイコのTIA-1ホモローグ(BmTRN-1)と相互作用するタンパク質の検索 (2010)
  • Author(s): 小谷英治・武藤清佳・福島真美・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] タンパク質固定化基材としての多角体 (2010)
  • Author(s): 井尻宏志・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] カイコサイポウイルス多角体へのBMP-2の固定化と前駆軟骨細胞の分化制御 (2010)
  • Author(s): 上田崇代・井尻宏志・森肇・川真田伸
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] DILP2固定化サイポウイルス多角体によるショウジョウバエの成長制御 (2010)
  • Author(s): 宮本哲幸・井尻宏志・井上喜博・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] カイコ絹糸腺におけるカイコサイポウイルス多角体タンパク質の発現 (2010)
  • Author(s): 山本賢二・小谷英治・小林功・瀬筒秀樹・田村俊樹・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] EGF固定化カイコサイポウイルス多角体によるヒト腸管上皮細胞の培養 (2010)
  • Author(s): 端汐美・井尻宏志・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Presentation] FGF-7固定化カイコサイポウイルス多角体によるヒト表皮角化細胞の細胞毒性物質からの保護 (2010)
  • Author(s): 山岡綾子・西村彦人・井尻宏志・森肇
  • Organizer: 日本蚕糸学会平成22年度合同支部大会
  • Place of Presentation: 浦添市・てだこホール
• [Remarks]
  • URL: http://kit-ibrc.com/research/
• [Remarks]
  • URL: https://sites.google.com/site/konchuukougaku/
• [Remarks]
  • URL: http://www.bio.kit.ac.jp/chromosome/INDEX.html
• [Remarks]
  • URL: https://sites.google.com/site/ibmrcdrosophila/home