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Coupling between Deformations of Vesicle and Chemical Stimuli: Approach from Soft Matter toward Cellular Life

Research Project

Project/Area Number 22244053
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics/Chemical physics
Research InstitutionTohoku University (2012-2013)
Ochanomizu University (2010-2011)

Principal Investigator

MASAYUKI Imai  東北大学, 理学(系)研究科(研究院), 教授 (60251485)

Co-Investigator(Kenkyū-buntansha) URAKAMI Naohito  山口大学, 大学院理工学研究科, 准教授 (50314795)
Project Period (FY) 2010-05-31 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥33,670,000 (Direct Cost: ¥25,900,000、Indirect Cost: ¥7,770,000)
Fiscal Year 2012: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2011: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2010: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
Keywords生命現象の物理 / ミニマルセル / ベシクル変形 / 自己生産 / 化学刺激 / 3次元計測 / 自己駆動 / 人工細胞 / 3次元形態観察 / 膜弾性エネルギー / チューブ形成 / DNAの自己複製 / Minimal Cell / ベシクル / 自発曲率 / 相分離 / 分裂 / ドメインダイナミクズ / シミュレーション
Research Abstract

We have investigated vesicle deformations triggered by chemical stimuli to reveal the pathway from vesicles (molecular assemblies of lipids) to cellular life. First we established an experimental technique to examine vesicle deformation triggered by the chemical stimuli and then revealed a mechanism of a tubular membrane formation induced by pH gradient. In addition we found that chemical stimuli drive vesicles toward the chemical source, so-called chemophoresis. These observations clearly show that the chemical stimuli play important roles to develop cellular life from vesicle. In addition we succeeded to reproduce a self-production of vesicle using binary vesicles, which shed light on the pathway toward the protopcell.

Report

(4 results)
  • 2013 Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (79 results)

All 2013 2012 2011 2010 Other

All Journal Article (22 results) (of which Peer Reviewed: 20 results) Presentation (49 results) (of which Invited: 10 results) Book (3 results) Remarks (5 results)

  • [Journal Article] Three-Dimensional Analysis of Lipid Vesicle Transformations2012

    • Author(s)
      A. Sakashita, N. Urakami, P. Ziherl, and M. Imai
    • Journal Title

      Soft Matter

      Volume: 8 Issue: 33 Pages: 8569-8581

    • DOI

      10.1039/c2sm25759a

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lipid membrane deformation in response to a local pH modification : theory and experiments2012

    • Author(s)
      A.-F. Bitbol, N. Puff, Y. Sakuma, M. Imai, J.-B. Fournier, and M. I
    • Journal Title

      Angelova, Soft Matter

      Volume: 8 Issue: 22 Pages: 6073-6082

    • DOI

      10.1039/c2sm25519g

    • Related Report
      2013 Final Research Report 2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of surfactant micelles in fluid and crystal phases2012

    • Author(s)
      M. Imai, M. Kurimoto, F. Matsuura, Y. Sakuma and T. Kawakatsu
    • Journal Title

      Soft Matter

      Volume: 8 Issue: 38 Pages: 9892-9905

    • DOI

      10.1039/c2sm07122c

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics of Heterogeneity in Fluid Membranes2012

    • Author(s)
      Shigeyuki Komura, Sanoop Ramachandran, Kazuhiko Seki,and Masayuki Imai
    • Journal Title

      Advances in Planar Lipid Bilayers and Liposomes

      Volume: 16 Pages: 129-164

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Model System of Self-Reproducing Vesicles2011

    • Author(s)
      Y. Sakuma and M. Imai
    • Journal Title

      Phys. Rev. Lett

      Volume: 107, 198101 Issue: 19 Pages: 1-5

    • DOI

      10.1103/physrevlett.107.198101

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular dynamics simulation for morphological change of water-in-oil microemulsion droplets induced by addition of polymer chains2011

    • Author(s)
      T. Kurokawa, N. Urakami, K. Nakaya-Yaegashi, A. Sakashita, M. Imai, and T. Yamamoto
    • Journal Title

      Soft Matter

      Volume: 7 Issue: 16 Pages: 7504-7510

    • DOI

      10.1039/c1sm05447c

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetric distribution of cone-shaped lipids in a highly curved bilayer revealed by a small angle neutron scattering technique2011

    • Author(s)
      Y. Sakuma, N. Urakami, T. Taniguchi, and M. Imai
    • Journal Title

      J. Phys. Cond. Matt

      Volume: 23 Issue: 28 Pages: 284104-284104

    • DOI

      10.1088/0953-8984/23/28/284104

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical investigations of the dynamics of two-component vesicles2011

    • Author(s)
      T. Taniguchi, M. Yanagisawa and M. Imai
    • Journal Title

      J. Phys. Cond. Matt

      Volume: 23 Issue: 28 Pages: 284103-284103

    • DOI

      10.1088/0953-8984/23/28/284103

    • NAID

      120003290262

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydrodynamic effects on concentration fluctuations in multicomponent membranes2011

    • Author(s)
      S. Ramachandran, S. Komura, K. Seki and M. Imai
    • Journal Title

      Soft Matter

      Volume: 7 Issue: 4 Pages: 1524-1531

    • DOI

      10.1039/c0sm00783h

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Periodic modulation of tubular vesicles induced by phase separation2010

    • Author(s)
      M. Yanagisawa, M. Imai, and T. Taniguchi
    • Journal Title

      Phys. Rev. E

      Volume: 82, 051928 Issue: 5 Pages: 1-9

    • DOI

      10.1103/physreve.82.051928

    • NAID

      120003537860

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Shape Deformation of Giant Vesicles Encapsulating Charged Colloidal Particles2010

    • Author(s)
      Y. Natsume, O. Pravaz, H. Yoshida1, and M. Imai
    • Journal Title

      Soft Matter

      Volume: 6 Issue: 21 Pages: 5359-5366

    • DOI

      10.1039/c0sm00396d

    • Related Report
      2013 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pore Formation in a Binary Giant Vesicle Induced by Cone-Shaped Lipids2010

    • Author(s)
      Y. Sakuma, T. Taniguchi, and M. Imai
    • Journal Title

      Biophys. J

      Volume: 99 Issue: 2 Pages: 472-479

    • DOI

      10.1016/j.bpj.2010.03.064

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Drag coefficient of a liquid domain in a two-dimensional membrane. S. Ramachandran2010

    • Author(s)
      S. Komura, M. Imai, and K. Seki
    • Journal Title

      Eur. Phys. J. E

      Volume: 31 Issue: 3 Pages: 303-310

    • DOI

      10.1140/epje/i2010-10577-3

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of domains on nanometer sized vesicle2010

    • Author(s)
      Y. Sakuma, N. Urakami, Y. Ogata, M. Nagao, S. Komura, T. Kawakatsu and M. Imai
    • Journal Title

      J. Phys. Conf. Ser

      Volume: 251, 012036 Pages: 1-4

    • DOI

      10.1088/1742-6596/251/1/012036

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of Domains on Nanometer Sized Vesicle2010

    • Author(s)
      Y.Sakuma, N.Urakami, Y.Ogata, M.Nagao, S.Komura, T.Ka wakatsu, M.Imai
    • Journal Title

      J.Phys.Conf.Ser.

      Volume: 251

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Periodic Modulation of Tubular Vesicles Induced by Phase Separation2010

    • Author(s)
      M.Yanagisawa, M.Imai, T.Taniguchi
    • Journal Title

      Phys.Rev.E

      Volume: 82

    • NAID

      120003537860

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pore Formation in a Binary Giant Vesicle Induced by Cone-Shaped Lipids2010

    • Author(s)
      Y.Sakuma, T.Taniguchi, M.Imai
    • Journal Title

      Biophys.J.

      Volume: 99 Pages: 472-479

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drag coefficient of a liquid domain in a two-dimensional membrane2010

    • Author(s)
      S.Ramachandran, S.Komura, M.Imai, K.Seki
    • Journal Title

      Eur.Phys.J.E

      Volume: 31 Pages: 303-310

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics of Heterogeneity in Fluid Membranes

    • Author(s)
      S.Komura, S.Ramacandran, K.Seki, M.Imai
    • Journal Title

      Advances in Planar Lipid Bilayers and Liposomes

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Numerical investigations of the dynamics of two-componentvesicles

    • Author(s)
      T.Taniguchi, M.Yanagisawa, M.Imai
    • Journal Title

      J.Phys.Cond.Matt.

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetric distribution of cone-shaped lipids in a highly curved hilaver revealed by a small angle neutron scattering technique

    • Author(s)
      Y.Sakuma, N.Urakami, T.Taniguchi, M.Imai
    • Journal Title

      J.Phys.Cond.Matt.

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydrodynamic effects on concentration fluctuations in multicomponent membranes

    • Author(s)
      S.Ramachandran, S.Komura, K.Seki, M.Imai
    • Journal Title

      Soft Matter

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 中性リン脂質ベシクルの化学駆動2013

    • Author(s)
      兒玉篤治,佐久間由香,今井正幸,川勝年洋
    • Organizer
      日本物理学会第68回年次大会
    • Place of Presentation
      広島, (口頭)
    • Year and Date
      2013-03-28
    • Related Report
      2013 Final Research Report
  • [Presentation] 化学刺激によるベシクル膜変形2013

    • Author(s)
      佐久間由香,A.-F. Bitbol, N. Puff,今井正幸,J.-B. Fournier, M. I. Angelova
    • Organizer
      日本物理学会第68回年次大会
    • Place of Presentation
      広島, (口頭)
    • Year and Date
      2013-03-28
    • Related Report
      2013 Final Research Report
  • [Presentation] Vesicle deformation triggered by chemical stimulation2013

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Self-organization and Emergent Dynamics in Active Soft Matter
    • Place of Presentation
      Kyoto, Japan, (Poster)
    • Year and Date
      2013-02-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Vesicle Dynamics Triggered by Chemical Stimuli2013

    • Author(s)
      M. Imai, A. Kodama, Y. Sakuma and T. Kawakatsu
    • Organizer
      German-Japan Workshop "Soft Matter in Nonequilibrium"
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2013-02-16
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Invited
  • [Presentation] Self-Reproduction of Lipid Vesicles2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Biomembrane Days
    • Place of Presentation
      Potsdam, Germany, (Poster)
    • Year and Date
      2012-09-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Self-Reproduction of Lipid Vesicles2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      ECI conference : Association in Solution III Self-Assembly : From Bio-Colloids to Nano-Engineering
    • Place of Presentation
      Bifröst, Iceland, (Poster)
    • Year and Date
      2012-07-25
    • Related Report
      2013 Final Research Report
  • [Presentation] Model Self-Reproducing Binary Vesicle2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      International Association of Colloid and Interface Scientists, Conference
    • Place of Presentation
      Sendai. Japan, (Oral)
    • Year and Date
      2012-05-14
    • Related Report
      2013 Final Research Report
  • [Presentation] ベシクル変形機構の解明;三次元画像解析によるアプローチ2012

    • Author(s)
      坂下あい, 浦上直人 , Primoz Ziherl, 今井正幸
    • Organizer
      日本物理学会第67回年次大会
    • Place of Presentation
      関西学院, (口頭)
    • Year and Date
      2012-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] ベシクル変形機構の解明;三次元画像解析によるアプローチ2012

    • Author(s)
      坂下あい, 浦上直人, Primoz Ziherl, 今井正幸
    • Organizer
      日本物理学会第67回年次大会
    • Place of Presentation
      関西学院、兵庫県
    • Year and Date
      2012-03-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Model of Self Reproducing Vesicles2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Biophysical Society 56th Annual Meeting
    • Place of Presentation
      San Diego, USA, (Oral)
    • Year and Date
      2012-02-26
    • Related Report
      2013 Final Research Report
  • [Presentation] Lipid Membrane Deformation in Response to a Local pH Modification2012

    • Author(s)
      A.-F. Bitbol, N. Puff, Y. Sakuma, M. Imai, J.-B. Fournier and M. Angelova
    • Organizer
      Biophysical Society 56th Annual Meeting
    • Place of Presentation
      San Diego, USA, (Oral)
    • Year and Date
      2012-02-26
    • Related Report
      2013 Final Research Report
  • [Presentation] Model of Self Reproducing Vesicles2012

    • Author(s)
      Y.Sakuma, M.Imai
    • Organizer
      Biophysical Society 56^<th> Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-02-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Lipid Membrane Deformation in Response to a Local pH Modification2012

    • Author(s)
      A.-F.Bitbol, N.Puff, Y.Sakuma, M.Imai, J.-B.Fournier, M.Angelova
    • Organizer
      Biophysical Society 56^<th> Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-02-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular Assembly to Protocell2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Japanese-German-French workshop"Physics of Active Soft Matter"
    • Place of Presentation
      Heidelberg, Germany
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Molecular assembly to protocell2012

    • Author(s)
      M. Imai and Y. Sakuma
    • Organizer
      ECI conference : Association in Solution III Self-Assembly : From Bio-Colloids to Nano-Engineering
    • Place of Presentation
      Bifröst, Iceland
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Model Self-Reproducing Binary Vesicle2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      International Association of Colloid and Interface Scientists Conference 2012
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Slow Dynamics of Soft Spheres2012

    • Author(s)
      M. Imai, M. Kurimoto, F. Matsuura, T. Kawakatsu and Y.Sakuma
    • Organizer
      International Association of Colloid and Interface Scientists Conference 2012
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular assembly to protocell2012

    • Author(s)
      M. Imai and Y. Sakuma
    • Organizer
      ECI conference: Association in Solution III
    • Place of Presentation
      Bifrost, Iceland
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Self-Reproduction of Lipid Vesicles2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      ECI conference: Association in Solution III
    • Place of Presentation
      Bifrost, Iceland
    • Related Report
      2012 Annual Research Report
  • [Presentation] Self-Reproduction of Lipid Vesicles2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Biomembrane Days in Potsdam
    • Place of Presentation
      Potsdam, Germany
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular Assembly to Protocell2012

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Japanese-German-French workshop “Physics of Active Soft Matter”
    • Place of Presentation
      Heidelberg, Germany
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Slow Dynamics of surfactant micelles in fluid and crystal phases2012

    • Author(s)
      M. Imai, M. Kurimoto, F. Matsuura and Y. Sakuma
    • Organizer
      4th International Symposium on Slow Dynamics in Complex Systems
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Asymmetric Distribution of Lipids Induced by Membrane Curvature2011

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      1st Asia-Oceania Conference on Neutron Scattering
    • Place of Presentation
      Tsukuba, Japan, (Poster)
    • Year and Date
      2011-11-22
    • Related Report
      2013 Final Research Report
  • [Presentation] Asymmetric Distribution of Lipids Induced by Membrane Curvature2011

    • Author(s)
      Y.Sakuma, M.Imai
    • Organizer
      1^<st> Asia-Oceania Conference on Neutron Scattering
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2011-11-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Slow dynamics of soft spheres2011

    • Author(s)
      M.Imai
    • Organizer
      1^<st> Asia-Oceania Conference on Neutron Scattering
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2011-11-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 膜の曲率に応じた脂質分布の非対称性2011

    • Author(s)
      佐久間由香,今井正幸
    • Organizer
      日本物理学会第66回年次大会
    • Place of Presentation
      富山, (口頭)
    • Year and Date
      2011-09-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 膜の曲率に応じた脂質分布の非対称性2011

    • Author(s)
      佐久間由香, 今井正幸
    • Organizer
      日本物理学会第66回年次大会
    • Place of Presentation
      富山、富山県
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Three-dimensional analysis of lipid vesicle transformations2011

    • Author(s)
      A. Sakashita, N. Urakami, P. Ziherl, and M. Imai
    • Organizer
      8th Liquid Matter Conference
    • Place of Presentation
      Wien, Austria, (Poster)
    • Year and Date
      2011-09-06
    • Related Report
      2013 Final Research Report
  • [Presentation] Three-dimensional analysis of lipid vesicle transformations2011

    • Author(s)
      A.Sakashita, N.Urakami, P.Ziherl, M.Imai
    • Organizer
      8^<th> Liquid Matter Conference
    • Place of Presentation
      Wien, Austria(招待講演)
    • Year and Date
      2011-09-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 三次元画像解析による生体膜変形機構の解明2011

    • Author(s)
      坂下あい、浦上直人、Primoz Ziherl、今井正幸
    • Organizer
      物理学会第66回年次大会
    • Place of Presentation
      新潟大学
    • Year and Date
      2011-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 中性子小角散乱でみたベシクルの構造2011

    • Author(s)
      佐久間由香,今井正幸
    • Organizer
      東京大学物性研究所短期研究会「小角・反射率・高分解能装置研究会」
    • Place of Presentation
      東京大学物性研究所, (口頭)
    • Year and Date
      2011-02-07
    • Related Report
      2013 Final Research Report
  • [Presentation] Slow dynamics in crystallization of soft spheres2011

    • Author(s)
      M. Imai
    • Organizer
      The 4^<th> international discussion meeting on glass transition
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Dynamics of Nanometer Sized Vesicles2011

    • Author(s)
      Y. Sakuma, N. Urakami, M. Nagao and M. Imai
    • Organizer
      The 4^<th> international discussion meeting on glass transition
    • Place of Presentation
      Sendai, Japan, (Poster)
    • Related Report
      2013 Final Research Report
  • [Presentation] 三次元画像解析による生体膜変形機構の解明2010

    • Author(s)
      坂下あい, 浦上直人, Primoz Ziherl, 今井正幸
    • Organizer
      日本物理学会平成22年度秋季大会
    • Place of Presentation
      大阪府立大学, (口頭)
    • Year and Date
      2010-09-26
    • Related Report
      2013 Final Research Report
  • [Presentation] ベシクルのバーシングダイナミクス2010

    • Author(s)
      佐久間由香, 今井正幸
    • Organizer
      日本物理学会平成22年度秋季大会
    • Place of Presentation
      大阪府立大学, (口頭)
    • Year and Date
      2010-09-25
    • Related Report
      2013 Final Research Report
  • [Presentation] Morphology Transitions of Surfactant Assemblies Induced by Confinement of Colloids2010

    • Author(s)
      M. Imai, Y. Suganuma, Y. Natsume
    • Organizer
      21st IUPAC International Conference on Chemical Thermodynamics
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2010-08-06
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Minimal Cellへの多成分ベシクルからのアプローチ2010

    • Author(s)
      佐久間由香・今井正幸
    • Organizer
      「細胞を創る」研究会3.0
    • Place of Presentation
      東京大学生産技術研究所
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Shape deformations of multi-component vesicles2010

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      467th Wilhelm and Else Heraeus Seminar BIOPHYSICS OF MEMBRANE TRANSFORMATIONS Workshop
    • Place of Presentation
      Bad Honnef, Germany
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Self-Birthing Vesicle2010

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      Wilhelm and Else Heraeus Seminar : BIOPHYSICS OF MEMBRANE TRANSFORMATIONS Workshop
    • Place of Presentation
      Bad Honnef, Germany, (Poster)
    • Related Report
      2013 Final Research Report
  • [Presentation] Cascade Birthing Dynamics of Vesicles2010

    • Author(s)
      Y. Sakuma, M. Imai
    • Organizer
      ISSP International Workshop on Soft Matter Physics
    • Place of Presentation
      Kashiwa, Japan, (Oral)
    • Related Report
      2013 Final Research Report
  • [Presentation] Three-Dimensional Analysis of Lipid Vesicle Morphologies2010

    • Author(s)
      A.Sakashita, N.Urakami, P. Ziherl, M.Imai
    • Organizer
      ISSP International Workshop on Soft Matter Physics
    • Place of Presentation
      Kashiwa, Japan, (Poster)
    • Related Report
      2013 Final Research Report
  • [Presentation] Deformation of Vesicles Controlled by Spontaneous Curvature of Lipids2010

    • Author(s)
      Y. Sakuma, T. Taniguchi, T. Kawakatsu and M. Imai
    • Organizer
      International Symposium on NonEquilibrium Soft Matter 2010
    • Place of Presentation
      Nara, (Poster)
    • Related Report
      2013 Final Research Report
  • [Presentation] Shape deformations of multi-component vesicles2010

    • Author(s)
      Y. Sakuma, M. Imai
    • Organizer
      International Symposium on NonEquilibrium Soft Matter 2010
    • Place of Presentation
      Nara
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 脂質の自発曲率が誘起するベシクル膜の変形2010

    • Author(s)
      佐久間由香、谷口貴志、川勝年洋、今井正幸
    • Organizer
      日本物理学会第65回年次大会
    • Place of Presentation
      岡山大学津島キャンパス, (口頭)
    • Related Report
      2013 Final Research Report
  • [Presentation] コロイドを内包したベシクルの形態転移2010

    • Author(s)
      夏目ゆうの、Olivier Pravaz、今井正幸
    • Organizer
      日本物理学会第65回年次大会
    • Place of Presentation
      岡山大学津島キャンパス, (口頭)
    • Related Report
      2013 Final Research Report
  • [Presentation] Shape Deformations of Multi-component Vesicles2010

    • Author(s)
      Y.Sakuma, M.Imai
    • Organizer
      467th Wilhelm and Else Heraeus Seminar BIOPHYSICS OF MEMBRANE TRANS FORMATIONS Workshop
    • Place of Presentation
      Bad Honnef, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Shape Deformations of Multi-component Vesicles2010

    • Author(s)
      Y.Sakuma, T.Taniguchi, S.Komura, T.Kawakatsu, M.Imai
    • Organizer
      International symposium on Non-Equilibrium Soft Matter
    • Place of Presentation
      Nara, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Inter-membrane Interactions Modulated by Addition of Guest Components2010

    • Author(s)
      M.Imai
    • Organizer
      21th IUPAC International Conference on Chemical Thermodynamics
    • Place of Presentation
      Tsukuba, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Minimal Cell への多成分ベシクルからのアプローチ2010

    • Author(s)
      佐久間由香 今井正幸
    • Organizer
      「細胞を創る」研究会3.0
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Book] Dynamics of Heterogeneity in Fluid Membranes, Advances in planar lipid bilayers and liposomes Vol. 16 (ed. Ales Iglic)2012

    • Author(s)
      S. Komura, S. Ramacandran, K. Seki, and M. Imai
    • Publisher
      Elsevier, Chapter 5
    • Related Report
      2013 Final Research Report
  • [Book] Shape deformations of multi-component vesicles, Advances in planar lipid bilayers and liposomes Vol. 12 (ed. Ales Iglic)2010

    • Author(s)
      M. Imai and Y. Sakuma
    • Publisher
      Elsevier, Chapter 3
    • Related Report
      2013 Final Research Report
  • [Book] Advances in planar lipid bilayers and liposomes Vol.12 chapter 3, Shape deformations of multi-component vesicles2010

    • Author(s)
      M.Imai, Y.Sakuma
    • Total Pages
      37
    • Publisher
      Elsevier
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.bio.phys.tohoku.ac.jp/

    • Related Report
      2013 Final Research Report
  • [Remarks] 日刊工業新聞 2011年12月5日 「お茶の水女子大、冷やすと内部薬剤を放出 するカプセル粒子を開発」

    • Related Report
      2013 Final Research Report
  • [Remarks] 日経産業新聞 2012年2月28日 「微小カプセル 冷却で薬剤放出」

    • Related Report
      2013 Final Research Report
  • [Remarks] 東北大学大学院理学研究科物理学専攻ソフトマター・生物物理研究室

    • URL

      http://www.bio.phys.tohoku.ac.jp/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://sofia.phys.ocha.ac.jp/imailab/index.html

    • Related Report
      2010 Annual Research Report

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Published: 2010-11-30   Modified: 2019-07-29  

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