Mechanisms that regulate remodeling and life-long maintenance ofadult-type neural circuits
| Project/Area Number |
22247034
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Kyoto University |
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Principal Investigator |
UEMURA Tadashi 京都大学, 大学院・生命科学研究科, 教授 (80213396)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥41,340,000 (Direct Cost: ¥31,800,000、Indirect Cost: ¥9,540,000)
Fiscal Year 2012: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2011: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2010: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
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| Keywords | 神経回路 / 樹状突起 / リモデリング / 神経変性 / 次世代シーケンサー / ショウジョウバエ |
|---|
| Research Abstract |
For the establishment of functional neural circuits that support a wide range of animal behaviors, initial circuits formed in early development have to be reorganized. One way to achieve this is local remodeling of the circuitry hardwiring. We genetically investigated the underlying mechanisms of this remodeling, and discovered a gene that scales the size of dendritic arbors with that of the adult body.
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Report
(4 results)
Research Products
(26 results)
